Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     665
NP_001091680                                                           19     665
NP_001091679                                                           19     665
XP_006713048                                                           19     665
XP_006713047                                                           19     665
XP_006713046                                                           19     665
XP_005264943                                                           19     665
NP_116196                                                              17    3301
NP_835363                                                              17    3301
NP_001245381                                                           17    3301
NP_001245382                                                           17    3301
XP_006717580                                                           17    3301
XP_006717579                                                           17    3301
NP_003970                                                              17    4312
NP_001008781                                                           16    5631
NP_001138528                                                           16    5631
NP_065161                                                              16    5631
XP_006718827                                                           16    5631
NP_001107595                                                           16    7355
NP_001244097                                                           16    7355
NP_005220                                                              16    7355
NP_079059                                                              16    7355
NP_006102                                                              16    7355
NP_005221                                                              16    7355
XP_006719338                                                           16    7355
XP_006718392                                                           16    7355
XP_006718390                                                           16    7355
XP_006718389                                                           16    7355
XP_005253195                                                           16    7355
NP_078959                                                              15    9605
NP_115732                                                              15    9605
NP_000831                                                              15    9605
NP_055656                                                              15    9605
NP_000835                                                              15    9605
NP_870989                                                              15    9605
NP_001120795                                                           15    9605
NP_001243738                                                           15    9605
NP_001229721                                                           15    9605
NP_001243742                                                           15    9605
NP_000832                                                              15    9605
NP_001243740                                                           15    9605
NP_001269776                                                           15    9605
NP_001229723                                                           15    9605
NP_001229722                                                           15    9605
NP_065962                                                              15    9605
NP_001243646                                                           15    9605
NP_000834                                                              15    9605
NP_001243741                                                           15    9605
XP_006722147                                                           15    9605
XP_005256880                                                           15    9605
XP_005256879                                                           15    9605
XP_005250743                                                           15    9605
XP_006716234                                                           15    9605
XP_006716001                                                           15    9605
XP_006715684                                                           15    9605
XP_006715683                                                           15    9605
XP_006715682                                                           15    9605
XP_006715681                                                           15    9605
XP_006715680                                                           15    9605
XP_006715679                                                           15    9605
XP_006715678                                                           15    9605
XP_005248827                                                           15    9605
XP_006715134                                                           15    9605
XP_005265152                                                           15    9605
XP_006713184                                                           15    9605
NP_000830                                                              15    9605
NP_000836                                                              15    9605
NP_001123535                                                           15    9605
>NP_001895
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 284 ALLNKTNV 291
>NP_001091680
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 284 ALLNKTNV 291
>NP_001091679
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 284 ALLNKTNV 291
>XP_006713048
          Length = 720

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 284 ALLNKTNV 291
>XP_006713047
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 277 ALLNKTNV 284
>XP_006713046
          Length = 774

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 277 ALLNKTNV 284
>XP_005264943
          Length = 781

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   ALLNKTNV 8
           ALLNKTNV
Sbjct: 284 ALLNKTNV 291
>NP_116196
          Length = 1094

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 796 ALLSRTNAN 804
>NP_835363
          Length = 1043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 745 ALLSRTNAN 753
>NP_001245381
          Length = 986

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 671 ALLSRTNAN 679
>NP_001245382
          Length = 969

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 671 ALLSRTNAN 679
>XP_006717580
          Length = 1043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 745 ALLSRTNAN 753
>XP_006717579
          Length = 1180

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALLNKTNVN 9
           ALL++TN N
Sbjct: 882 ALLSRTNAN 890
>NP_003970
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           +N+TNVN
Sbjct: 157 MNRTNVN 163
>NP_001008781
          Length = 4557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ALLNKTN 7
            ALLNK+N
Sbjct: 4199 ALLNKSN 4205
>NP_001138528
          Length = 704

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLNKTN 7
           LLNKTN
Sbjct: 693 LLNKTN 698
>NP_065161
          Length = 706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLNKTN 7
           LLNKTN
Sbjct: 695 LLNKTN 700
>XP_006718827
          Length = 3479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    ALLNKTN 7
            ALLNK+N
Sbjct: 3089 ALLNKSN 3095
>NP_001107595
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          NKTN+N
Sbjct: 51 NKTNMN 56
>NP_001244097
          Length = 95

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          NKTN+N
Sbjct: 51 NKTNMN 56
>NP_005220
          Length = 428

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          NKTN+N
Sbjct: 51 NKTNMN 56
>NP_079059
          Length = 902

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           LN+TN+N
Sbjct: 814 LNETNLN 820
>NP_006102
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           ++KTNVN
Sbjct: 338 ISKTNVN 344
>NP_005221
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          NKTN+N
Sbjct: 50 NKTNMN 55
>XP_006719338
          Length = 407

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          NKTN+N
Sbjct: 50 NKTNMN 55
>XP_006718392
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           LN+TN+N
Sbjct: 678 LNETNLN 684
>XP_006718390
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           LN+TN+N
Sbjct: 758 LNETNLN 764
>XP_006718389
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           LN+TN+N
Sbjct: 776 LNETNLN 782
>XP_005253195
          Length = 864

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LNKTNVN 9
           LN+TN+N
Sbjct: 776 LNETNLN 782
>NP_078959
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ALLNKT 6
           ALLNKT
Sbjct: 259 ALLNKT 264
>NP_115732
          Length = 173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ALLNKT 6
           ALLNKT
Sbjct: 95  ALLNKT 100
>NP_000831
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 658 ALLTKTN 664
>NP_055656
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>NP_000835
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 672 ALLTKTN 678
>NP_870989
          Length = 922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 672 ALLTKTN 678
>NP_001120795
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 665 ALLTKTN 671
>NP_001243738
          Length = 796

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 553 ALLTKTN 559
>NP_001229721
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>NP_001243742
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 536 ALLTKTN 542
>NP_000832
          Length = 912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 669 ALLTKTN 675
>NP_001243740
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 622 ALLTKTN 628
>NP_001269776
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 361 ALLTKTN 367
>NP_001229723
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>NP_001229722
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>NP_065962
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    LLNKTN 7
            +LNKTN
Sbjct: 1130 ILNKTN 1135
>NP_001243646
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 15 NETNVN 20
>NP_000834
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 667 ALLTKTN 673
>NP_001243741
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 500 ALLTKTN 506
>XP_006722147
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   ALLNKT 6
           ALLNKT
Sbjct: 144 ALLNKT 149
>XP_005256880
          Length = 125

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ALLNKT 6
          ALLNKT
Sbjct: 47 ALLNKT 52
>XP_005256879
          Length = 135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ALLNKT 6
          ALLNKT
Sbjct: 47 ALLNKT 52
>XP_005250743
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    LLNKTN 7
            +LNKTN
Sbjct: 1130 ILNKTN 1135
>XP_006716234
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    LLNKTN 7
            +LNKTN
Sbjct: 1130 ILNKTN 1135
>XP_006716001
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 665 ALLTKTN 671
>XP_006715684
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715683
          Length = 827

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715682
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715681
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715680
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715679
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715678
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_005248827
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  NKTNVN 9
          N+TNVN
Sbjct: 50 NETNVN 55
>XP_006715134
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 283 ALLTKTN 289
>XP_005265152
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 672 ALLTKTN 678
>XP_006713184
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 649 ALLTKTN 655
>NP_000830
          Length = 872

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 649 ALLTKTN 655
>NP_000836
          Length = 908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   ALLNKTN 7
           ALL KTN
Sbjct: 665 ALLTKTN 671
>NP_001123535
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ALLNKTN 7
          ALL KTN
Sbjct: 31 ALLTKTN 37
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.120    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,701
Number of extensions: 762
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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