Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
NP_001367                                                              17    3301
NP_619635                                                              17    3301
NP_056372                                                              17    4312
NP_005843                                                              17    4312
NP_001005273                                                           17    4312
NP_001264                                                              17    4312
XP_006721493                                                           17    4312
XP_006721492                                                           17    4312
XP_006721491                                                           17    4312
XP_006721490                                                           17    4312
XP_006721489                                                           17    4312
XP_006721488                                                           17    4312
XP_005256486                                                           17    4312
XP_005256485                                                           17    4312
XP_006721487                                                           17    4312
XP_006721486                                                           17    4312
XP_005256484                                                           17    4312
XP_006719025                                                           17    4312
XP_005253725                                                           17    4312
XP_006719024                                                           17    4312
XP_006719023                                                           17    4312
XP_006719022                                                           17    4312
XP_006719021                                                           17    4312
NP_001005271                                                           17    4312
NP_001138818                                                           16    5631
NP_001013012                                                           16    5631
XP_005257123                                                           16    5631
XP_005252043                                                           16    5631
NP_004332                                                              16    7355
XP_005264615                                                           16    7355
XP_006712164                                                           16    7355
XP_005264614                                                           16    7355
XP_005264613                                                           16    7355
XP_005264612                                                           16    7355
XP_005276104                                                           16    7355
NP_065194                                                              15    9605
NP_849172                                                              15    9605
NP_001073866                                                           15    9605
NP_001273358                                                           15    9605
NP_660333                                                              15    9605
NP_001182474                                                           15    9605
NP_848599                                                              15    9605
NP_071325                                                              15    9605
NP_998778                                                              15    9605
NP_003732                                                              15    9605
XP_005248194                                                           15    9605
XP_006713920                                                           15    9605
XP_006713919                                                           15    9605
XP_005247908                                                           15    9605
XP_005247907                                                           15    9605
XP_005247906                                                           15    9605
XP_005247905                                                           15    9605
XP_006713081                                                           15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ALLARMGG 8
            ALLARMGG
Sbjct: 3738 ALLARMGG 3745
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ALLARMGG 8
            ALLARMGG
Sbjct: 3730 ALLARMGG 3737
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ALLARMGG 8
            ALLARMGG
Sbjct: 3691 ALLARMGG 3698
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ALLARMGG 8
            ALLARMGG
Sbjct: 3770 ALLARMGG 3777
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ALLARMGG 8
            ALLARMGG
Sbjct: 3783 ALLARMGG 3790
>NP_001367
          Length = 4646

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            AL AR+GGS
Sbjct: 1895 ALEARLGGS 1903
>NP_619635
          Length = 1043

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  LLARMGGS 9
          +LAR+GGS
Sbjct: 29 VLARLGGS 36
>NP_056372
          Length = 1954

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1411 LLARVGGN 1418
>NP_005843
          Length = 1966

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>NP_001005273
          Length = 2000

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>NP_001264
          Length = 1912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1403 LLARVGGN 1410
>XP_006721493
          Length = 2056

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1454 LLARVGGN 1461
>XP_006721492
          Length = 1924

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721491
          Length = 2025

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721490
          Length = 2036

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1379 LLARVGGN 1386
>XP_006721489
          Length = 2045

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721488
          Length = 2056

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1399 LLARVGGN 1406
>XP_005256486
          Length = 2060

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_005256485
          Length = 2080

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006721487
          Length = 2111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1454 LLARVGGN 1461
>XP_006721486
          Length = 2114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_005256484
          Length = 2115

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>XP_006719025
          Length = 1902

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1390 LLARVGGN 1397
>XP_005253725
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1396 LLARVGGN 1403
>XP_006719024
          Length = 1908

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1396 LLARVGGN 1403
>XP_006719023
          Length = 1914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1402 LLARVGGN 1409
>XP_006719022
          Length = 1915

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1403 LLARVGGN 1410
>XP_006719021
          Length = 1940

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1431 LLARVGGN 1438
>NP_001005271
          Length = 2059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    LLARMGGS 9
            LLAR+GG+
Sbjct: 1458 LLARVGGN 1465
>NP_001138818
          Length = 1067

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LARMGGS 9
           LAR+GGS
Sbjct: 213 LARIGGS 219
>NP_001013012
          Length = 437

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ALLARMGGS 9
           ALL RMG S
Sbjct: 217 ALLTRMGES 225
>XP_005257123
          Length = 803

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   ARMGGS 9
           ARMGGS
Sbjct: 209 ARMGGS 214
>XP_005252043
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ALLARMGGS 9
           ALL RMG S
Sbjct: 113 ALLTRMGES 121
>NP_004332
          Length = 2225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1982 AAMARLGGA 1990
>XP_005264615
          Length = 2162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1919 AAMARLGGA 1927
>XP_006712164
          Length = 2179

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1936 AAMARLGGA 1944
>XP_005264614
          Length = 2191

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1948 AAMARLGGA 1956
>XP_005264613
          Length = 2208

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1965 AAMARLGGA 1973
>XP_005264612
          Length = 2242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ALLARMGGS 9
            A +AR+GG+
Sbjct: 1999 AAMARLGGA 2007
>XP_005276104
          Length = 338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ALLARMGGS 9
           ALL R GG+
Sbjct: 131 ALLLRFGGA 139
>NP_065194
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ALLARMGGS 9
            ALL+ M GS
Sbjct: 1652 ALLSHMAGS 1660
>NP_849172
          Length = 1065

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ALLARMGG 8
          ALL+++GG
Sbjct: 69 ALLSKVGG 76
>NP_001073866
          Length = 782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ALLARMGG 8
           ALLA +GG
Sbjct: 269 ALLAGLGG 276
>NP_001273358
          Length = 658

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLARMGG 8
          A+LAR GG
Sbjct: 16 AVLARPGG 23
>NP_660333
          Length = 1321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLARMGG 8
          ALLA +GG
Sbjct: 23 ALLALLGG 30
>NP_001182474
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ALLARMGG 8
           ALL  MGG
Sbjct: 224 ALLVTMGG 231
>NP_848599
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ALLARMGGS 9
            ALL  +GGS
Sbjct: 2253 ALLVGLGGS 2261
>NP_071325
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALLARMG 7
           ALLAR+G
Sbjct: 511 ALLARIG 517
>NP_998778
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALLARMG 7
           ALLAR+G
Sbjct: 511 ALLARIG 517
>NP_003732
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLARMGGS 9
           LLA +GGS
Sbjct: 570 LLAGLGGS 577
>XP_005248194
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALLARMGG 8
          ALLA +GG
Sbjct: 23 ALLALLGG 30
>XP_006713920
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALLARMG 7
           ALLAR+G
Sbjct: 511 ALLARIG 517
>XP_006713919
          Length = 701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   ALLARMG 7
           ALLAR+G
Sbjct: 511 ALLARIG 517
>XP_005247908
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLARMGGS 9
           LLA +GGS
Sbjct: 597 LLAGLGGS 604
>XP_005247907
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLARMGGS 9
           LLA +GGS
Sbjct: 570 LLAGLGGS 577
>XP_005247906
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLARMGGS 9
           LLA +GGS
Sbjct: 597 LLAGLGGS 604
>XP_005247905
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LLARMGGS 9
           LLA +GGS
Sbjct: 597 LLAGLGGS 604
>XP_006713081
          Length = 3964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ALLARMGGS 9
            ALL  +GGS
Sbjct: 2276 ALLVGLGGS 2284
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.135    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 517,401
Number of extensions: 656
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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