Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           20     390
NP_001257437                                                           20     390
NP_006281                                                              20     390
XP_005267176                                                           20     390
NP_694984                                                              17    2528
XP_006724701                                                           17    2528
XP_005262172                                                           17    2528
XP_005262170                                                           17    2528
NP_057692                                                              17    3301
NP_004509                                                              17    4312
NP_742106                                                              17    4312
NP_742105                                                              17    4312
NP_742104                                                              17    4312
NP_742107                                                              17    4312
XP_006723855                                                           17    4312
XP_006723854                                                           17    4312
XP_006723853                                                           17    4312
XP_006723852                                                           17    4312
XP_006723851                                                           17    4312
XP_006723850                                                           17    4312
NP_689914                                                              16    5631
NP_055983                                                              16    5631
NP_722576                                                              16    5631
XP_005262424                                                           16    5631
XP_005258735                                                           16    5631
XP_005258734                                                           16    5631
XP_005258733                                                           16    5631
XP_006723176                                                           16    5631
NP_001245298                                                           16    7355
NP_001245297                                                           16    7355
NP_001035982                                                           16    7355
NP_001245295                                                           16    7355
NP_001245296                                                           16    7355
NP_001245299                                                           16    7355
XP_006719939                                                           16    7355
XP_005252490                                                           16    7355
XP_005252488                                                           16    7355
NP_112194                                                              16    7355
NP_001177957                                                           15    9605
NP_036602                                                              15    9605
NP_065866                                                              15    9605
NP_116586                                                              15    9605
NP_085135                                                              15    9605
NP_001193940                                                           15    9605
NP_055885                                                              15    9605
NP_671693                                                              15    9605
NP_001833                                                              15    9605
XP_005258413                                                           15    9605
XP_005266369                                                           15    9605
XP_005266368                                                           15    9605
XP_005266367                                                           15    9605
XP_005266366                                                           15    9605
XP_005266365                                                           15    9605
XP_005266364                                                           15    9605
XP_005266363                                                           15    9605
XP_005266362                                                           15    9605
XP_005266361                                                           15    9605
XP_005266359                                                           15    9605
XP_005266360                                                           15    9605
XP_005266358                                                           15    9605
XP_006716783                                                           15    9605
XP_005251420                                                           15    9605
XP_005251419                                                           15    9605
XP_006715974                                                           15    9605
>NP_001257436
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ALFSTIKET 9
           ALFST+KET
Sbjct: 125 ALFSTLKET 133
>NP_001257437
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ALFSTIKET 9
           ALFST+KET
Sbjct: 125 ALFSTLKET 133
>NP_006281
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ALFSTIKET 9
           ALFST+KET
Sbjct: 125 ALFSTLKET 133
>XP_005267176
          Length = 790

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   ALFSTIKET 9
           ALFST+KET
Sbjct: 125 ALFSTLKET 133
>NP_694984
          Length = 1802

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    FSTIKET 9
            FST+KET
Sbjct: 1372 FSTVKET 1378
>XP_006724701
          Length = 1398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   FSTIKET 9
           FST+KET
Sbjct: 968 FSTVKET 974
>XP_005262172
          Length = 1631

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    FSTIKET 9
            FST+KET
Sbjct: 1201 FSTVKET 1207
>XP_005262170
          Length = 1752

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    FSTIKET 9
            FST+KET
Sbjct: 1322 FSTVKET 1328
>NP_057692
          Length = 453

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ALF+T+KE
Sbjct: 110 ALFNTLKE 117
>NP_004509
          Length = 844

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742106
          Length = 841

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742105
          Length = 872

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742104
          Length = 854

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_742107
          Length = 393

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723855
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723854
          Length = 858

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723853
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723852
          Length = 876

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723851
          Length = 885

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>XP_006723850
          Length = 886

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALFSTIKE 8
           ++FSTIKE
Sbjct: 110 SVFSTIKE 117
>NP_689914
          Length = 5058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    LFSTIKET 9
            +FS++KET
Sbjct: 2328 IFSSLKET 2335
>NP_055983
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF T+K+T
Sbjct: 1255 LFGTVKQT 1262
>NP_722576
          Length = 3080

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALFSTIKET 9
           +LFSTI+ T
Sbjct: 402 SLFSTIEST 410
>XP_005262424
          Length = 2875

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALFSTIKET 9
           +LFSTI+ T
Sbjct: 197 SLFSTIEST 205
>XP_005258735
          Length = 1254

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF T+K+T
Sbjct: 1206 LFGTVKQT 1213
>XP_005258734
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF T+K+T
Sbjct: 1214 LFGTVKQT 1221
>XP_005258733
          Length = 1267

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF T+K+T
Sbjct: 1219 LFGTVKQT 1226
>XP_006723176
          Length = 1303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF T+K+T
Sbjct: 1255 LFGTVKQT 1262
>NP_001245298
          Length = 1112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 424 VWSTVKET 431
>NP_001245297
          Length = 1123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 354 VWSTVKET 361
>NP_001035982
          Length = 1193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 424 VWSTVKET 431
>NP_001245295
          Length = 1182

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 413 VWSTVKET 420
>NP_001245296
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 378 VWSTVKET 385
>NP_001245299
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 161 VWSTVKET 168
>XP_006719939
          Length = 930

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 161 VWSTVKET 168
>XP_005252490
          Length = 761

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ALFSTIKE 8
          +LF T+KE
Sbjct: 40 SLFDTVKE 47
>XP_005252488
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  ALFSTIKE 8
          +LF T+KE
Sbjct: 40 SLFDTVKE 47
>NP_112194
          Length = 849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LFSTIKET 9
           ++ST+KET
Sbjct: 161 VWSTVKET 168
>NP_001177957
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LFSTIKE 8
           L+ST+KE
Sbjct: 423 LYSTLKE 429
>NP_036602
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LFSTIKE 8
           L+ST+KE
Sbjct: 423 LYSTLKE 429
>NP_065866
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FSTIKE 8
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_116586
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   FSTIKE 8
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_085135
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    LFSTIKET 9
            LF T KET
Sbjct: 1120 LFQTSKET 1127
>NP_001193940
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>NP_055885
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1542 LFAKVKET 1549
>NP_671693
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>NP_001833
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_005258413
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    LFSTIKET 9
            LF T KET
Sbjct: 1121 LFQTSKET 1128
>XP_005266369
          Length = 1564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1542 LFAKVKET 1549
>XP_005266368
          Length = 1668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1541 LFAKVKET 1548
>XP_005266367
          Length = 1669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1542 LFAKVKET 1549
>XP_005266366
          Length = 1669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1542 LFAKVKET 1549
>XP_005266365
          Length = 1669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1542 LFAKVKET 1549
>XP_005266364
          Length = 1696

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1569 LFAKVKET 1576
>XP_005266363
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_005266362
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_005266361
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_005266359
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_005266360
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_005266358
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    LFSTIKET 9
            LF+ +KET
Sbjct: 1570 LFAKVKET 1577
>XP_006716783
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_005251420
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_005251419
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LFSTIK 7
           LFSTIK
Sbjct: 171 LFSTIK 176
>XP_006715974
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LFSTIKE 8
           L+ST+KE
Sbjct: 375 LYSTLKE 381
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.124    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 416,202
Number of extensions: 849
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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