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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              20     509
XP_005266703                                                           20     509
NP_056169                                                              17    2528
NP_689846                                                              17    4312
NP_001018123                                                           17    4312
NP_061830                                                              17    4312
NP_001252516                                                           16    7355
NP_775960                                                              16    7355
NP_008877                                                              16    7355
NP_056382                                                              16    7355
NP_066022                                                              16    7355
NP_003119                                                              16    7355
XP_006723369                                                           16    7355
XP_005254096                                                           16    7355
XP_005254095                                                           16    7355
XP_005274250                                                           16    7355
XP_006718734                                                           16    7355
XP_006718733                                                           16    7355
XP_005274249                                                           16    7355
XP_006712150                                                           16    7355
XP_005264574                                                           16    7355
NP_004760                                                              15    9605
NP_064717                                                              15    9605
NP_064718                                                              15    9605
NP_001020029                                                           15    9605
NP_851825                                                              15    9605
NP_001229347                                                           15    9605
NP_001229346                                                           15    9605
NP_001229345                                                           15    9605
NP_000338                                                              15    9605
NP_653175                                                              15    9605
NP_851808                                                              15    9605
XP_006720376                                                           15    9605
XP_006720375                                                           15    9605
XP_006720374                                                           15    9605
XP_006720373                                                           15    9605
XP_006720372                                                           15    9605
XP_006720371                                                           15    9605
XP_006720370                                                           15    9605
XP_006720369                                                           15    9605
XP_006720304                                                           15    9605
XP_005268080                                                           15    9605

>NP_443179
          Length = 2170

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ALADRRESH 9
            ALAD RESH
Sbjct: 1306 ALADSRESH 1314



>XP_005266703
          Length = 1501

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ALADRRESH 9
           ALAD RESH
Sbjct: 637 ALADSRESH 645



>NP_056169
          Length = 1749

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           AL DRRE H
Sbjct: 286 ALDDRRELH 294



>NP_689846
          Length = 859

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALADRRES 8
           AL+DRRE+
Sbjct: 801 ALSDRREN 808



>NP_001018123
          Length = 859

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ALADRRES 8
           AL+DRRE+
Sbjct: 801 ALSDRREN 808



>NP_061830
          Length = 701

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ALADRRESH 9
           ALA+ RE+H
Sbjct: 248 ALAELRENH 256



>NP_001252516
          Length = 157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  DRRESH 9
          D+RESH
Sbjct: 63 DQRESH 68



>NP_775960
          Length = 1285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   LADRRESH 9
           LADR E H
Sbjct: 126 LADRYECH 133



>NP_008877
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 50 ALADEREA 57



>NP_056382
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRRESH 9
           +RRESH
Sbjct: 821 ERRESH 826



>NP_066022
          Length = 2564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 54 ALADEREA 61



>NP_003119
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 47 ALADEREA 54



>XP_006723369
          Length = 2394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 54 ALADEREA 61



>XP_005254096
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRRESH 9
           +RRESH
Sbjct: 821 ERRESH 826



>XP_005254095
          Length = 958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DRRESH 9
           +RRESH
Sbjct: 821 ERRESH 826



>XP_005274250
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 50 ALADEREA 57



>XP_006718734
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 50 ALADEREA 57



>XP_006718733
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 50 ALADEREA 57



>XP_005274249
          Length = 2390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 50 ALADEREA 57



>XP_006712150
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 47 ALADEREA 54



>XP_005264574
          Length = 2364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ALADRRES 8
          ALAD RE+
Sbjct: 47 ALADEREA 54



>NP_004760
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  DRRESH 9
          D RESH
Sbjct: 77 DERESH 82



>NP_064717
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  DRRESH 9
          D RESH
Sbjct: 77 DERESH 82



>NP_064718
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  DRRESH 9
          D RESH
Sbjct: 77 DERESH 82



>NP_001020029
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ALADRRE 7
          ALAD RE
Sbjct: 47 ALADERE 53



>NP_851825
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 404 SLHDRKERH 412



>NP_001229347
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 477 SLHDRKERH 485



>NP_001229346
          Length = 600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 496 SLHDRKERH 504



>NP_001229345
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 404 SLHDRKERH 412



>NP_000338
          Length = 2137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ALADRRE 7
          ALAD RE
Sbjct: 47 ALADERE 53



>NP_653175
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 465 SLHDRKERH 473



>NP_851808
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 465 SLHDRKERH 473



>XP_006720376
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 208 SLHDRKERH 216



>XP_006720375
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 208 SLHDRKERH 216



>XP_006720374
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 292 SLHDRKERH 300



>XP_006720373
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 292 SLHDRKERH 300



>XP_006720372
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 292 SLHDRKERH 300



>XP_006720371
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 404 SLHDRKERH 412



>XP_006720370
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 465 SLHDRKERH 473



>XP_006720369
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ALADRRESH 9
           +L DR+E H
Sbjct: 465 SLHDRKERH 473



>XP_006720304
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ALADRRE 7
          ALAD RE
Sbjct: 47 ALADERE 53



>XP_005268080
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  ALADRRE 7
          ALAD RE
Sbjct: 47 ALADERE 53



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.123    0.333 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,730
Number of extensions: 915
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)