Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_057225                                                              18    1482
NP_004963                                                              18    1935
XP_005251512                                                           18    1935
NP_001273648                                                           17    4312
NP_057117                                                              17    4312
NP_006132                                                              17    4312
NP_001273086                                                           17    4312
XP_006716637                                                           17    4312
XP_005251005                                                           17    4312
XP_006716636                                                           17    4312
XP_005251004                                                           17    4312
XP_005251002                                                           17    4312
XP_005251001                                                           17    4312
NP_002379                                                              16    5631
NP_001257401                                                           16    5631
NP_001753                                                              16    5631
NP_150091                                                              16    5631
NP_001121689                                                           16    5631
NP_006575                                                              16    5631
NP_001180458                                                           16    5631
XP_006721705                                                           16    5631
XP_006721704                                                           16    5631
NP_001360                                                              16    7355
NP_002935                                                              16    7355
NP_115717                                                              16    7355
NP_057613                                                              16    7355
NP_003326                                                              16    7355
XP_006719899                                                           16    7355
XP_006719898                                                           16    7355
XP_006719897                                                           16    7355
XP_006719896                                                           16    7355
XP_006719895                                                           16    7355
XP_005266476                                                           16    7355
XP_006715611                                                           16    7355
XP_005248319                                                           16    7355
XP_005265487                                                           16    7355
XP_006713384                                                           16    7355
NP_001001711                                                           16    7355
NP_940980                                                              15    9605
NP_061159                                                              15    9605
NP_001171134                                                           15    9605
NP_060621                                                              15    9605
NP_001171136                                                           15    9605
NP_001099001                                                           15    9605
NP_079114                                                              15    9605
NP_065870                                                              15    9605
NP_001156001                                                           15    9605
XP_005254625                                                           15    9605
XP_005254624                                                           15    9605
XP_005268686                                                           15    9605
XP_005252654                                                           15    9605
XP_005248808                                                           15    9605
XP_005248807                                                           15    9605
XP_005248806                                                           15    9605
XP_005248805                                                           15    9605
XP_005248804                                                           15    9605
XP_005248803                                                           15    9605
XP_005248802                                                           15    9605
XP_005248801                                                           15    9605
XP_005248800                                                           15    9605
XP_006712674                                                           15    9605
XP_006712673                                                           15    9605
XP_006712672                                                           15    9605
XP_005246722                                                           15    9605
NP_001171135                                                           15    9605
>NP_057225
          Length = 523

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  KNILLIGE 9
          KN+LL+GE
Sbjct: 68 KNVLLLGE 75
>NP_004963
          Length = 1132

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AKNILLIGE 9
           AKNILLI E
Sbjct: 676 AKNILLIRE 684
>XP_005251512
          Length = 1132

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AKNILLIGE 9
           AKNILLI E
Sbjct: 676 AKNILLIRE 684
>NP_001273648
          Length = 284

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 230 SKNLLLLGK 238
>NP_057117
          Length = 314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 260 SKNLLLLGK 268
>NP_006132
          Length = 492

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KNILLIGE 9
          KNIL+ GE
Sbjct: 55 KNILVFGE 62
>NP_001273086
          Length = 415

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  KNILLIGE 9
          KNIL+ GE
Sbjct: 55 KNILVFGE 62
>XP_006716637
          Length = 305

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 260 SKNLLLLGK 268
>XP_005251005
          Length = 339

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 216 SKNLLLLGK 224
>XP_006716636
          Length = 339

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 216 SKNLLLLGK 224
>XP_005251004
          Length = 353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 230 SKNLLLLGK 238
>XP_005251002
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 260 SKNLLLLGK 268
>XP_005251001
          Length = 383

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           +KN+LL+G+
Sbjct: 260 SKNLLLLGK 268
>NP_002379
          Length = 853

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           NILLIG+
Sbjct: 385 NILLIGD 391
>NP_001257401
          Length = 818

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           NILLIG+
Sbjct: 350 NILLIGD 356
>NP_001753
          Length = 531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>NP_150091
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KNILLIGE 9
           KN+ L+GE
Sbjct: 424 KNMFLVGE 431
>NP_001121689
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KNILLIGE 9
           KN+ L+GE
Sbjct: 424 KNMFLVGE 431
>NP_006575
          Length = 530

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>NP_001180458
          Length = 493

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>XP_006721705
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  NILLIGE 9
          N+L+IGE
Sbjct: 29 NVLIIGE 35
>XP_006721704
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NILLIGE 9
           N+L+IGE
Sbjct: 95  NVLIIGE 101
>NP_001360
          Length = 4624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KNILLIGE 9
            K +LLIGE
Sbjct: 2584 KAVLLIGE 2591
>NP_002935
          Length = 2347

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    AKNILLIGE 9
            ++NI+L+G+
Sbjct: 1845 SENIILVGD 1853
>NP_115717
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+L+IG
Sbjct: 338 KNVLVIG 344
>NP_057613
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 669 KNLLLLG 675
>NP_003326
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AKNILLIG 8
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>XP_006719899
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719898
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719897
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006719896
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 486 KNLLLLG 492
>XP_006719895
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 563 KNLLLLG 569
>XP_005266476
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+LL+G
Sbjct: 629 KNLLLLG 635
>XP_006715611
          Length = 2342

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    AKNILLIGE 9
            ++NI+L+G+
Sbjct: 1840 SENIILVGD 1848
>XP_005248319
          Length = 4609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KNILLIGE 9
            K +LLIGE
Sbjct: 2569 KAVLLIGE 2576
>XP_005265487
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AKNILLIG 8
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>XP_006713384
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AKNILLIG 8
          AKN++L+G
Sbjct: 48 AKNLVLMG 55
>NP_001001711
          Length = 396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KNILLIG 8
           KN+L+IG
Sbjct: 346 KNVLVIG 352
>NP_940980
          Length = 2527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    KNILLIG 8
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>NP_061159
          Length = 1361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           ++NI+++GE
Sbjct: 495 SRNIIVMGE 503
>NP_001171134
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2298 AKNIKTIGD 2306
>NP_060621
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2324 AKNIKTIGD 2332
>NP_001171136
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2298 AKNIKTIGD 2306
>NP_001099001
          Length = 1319

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1219 KNVVLVG 1225
>NP_079114
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KNILLIG 8
          KNI+L+G
Sbjct: 56 KNIILMG 62
>NP_065870
          Length = 1302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1202 KNVVLVG 1208
>NP_001156001
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>XP_005254625
          Length = 1361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           ++NI+++GE
Sbjct: 495 SRNIIVMGE 503
>XP_005254624
          Length = 1361

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AKNILLIGE 9
           ++NI+++GE
Sbjct: 495 SRNIIVMGE 503
>XP_005268686
          Length = 2521

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    KNILLIG 8
            KN LL+G
Sbjct: 2260 KNFLLVG 2266
>XP_005252654
          Length = 743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KNILLIG 8
          KNI+L+G
Sbjct: 56 KNIILMG 62
>XP_005248808
          Length = 1121

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1021 KNVVLVG 1027
>XP_005248807
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1082 KNVVLVG 1088
>XP_005248806
          Length = 1317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1217 KNVVLVG 1223
>XP_005248805
          Length = 1345

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1245 KNVVLVG 1251
>XP_005248804
          Length = 1378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1278 KNVVLVG 1284
>XP_005248803
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1355 KNVVLVG 1361
>XP_005248802
          Length = 1515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1415 KNVVLVG 1421
>XP_005248801
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
>XP_005248800
          Length = 1541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    KNILLIG 8
            KN++L+G
Sbjct: 1441 KNVVLVG 1447
>XP_006712674
          Length = 2436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2288 AKNIKTIGD 2296
>XP_006712673
          Length = 2441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2293 AKNIKTIGD 2301
>XP_006712672
          Length = 2443

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2295 AKNIKTIGD 2303
>XP_005246722
          Length = 2472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2324 AKNIKTIGD 2332
>NP_001171135
          Length = 2446

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AKNILLIGE 9
            AKNI  IG+
Sbjct: 2298 AKNIKTIGD 2306
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.146    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 408,911
Number of extensions: 892
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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