Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              20     390
NP_001087241                                                           20     390
XP_006714101                                                           20     390
XP_005265799                                                           20     390
XP_005265798                                                           20     390
XP_005265797                                                           20     390
NP_001034589                                                           17    3301
XP_006710423                                                           17    3301
NP_689500                                                              16    5631
NP_055437                                                              16    5631
NP_001106997                                                           16    5631
NP_938057                                                              16    5631
XP_005256385                                                           16    5631
XP_006721400                                                           16    5631
XP_005256381                                                           16    5631
NP_001123614                                                           16    5631
NP_001240813                                                           16    7355
NP_803876                                                              16    7355
NP_001257321                                                           16    7355
NP_001257320                                                           16    7355
NP_958834                                                              16    7355
NP_003254                                                              16    7355
NP_079420                                                              16    7355
NP_001095876                                                           16    7355
XP_006721109                                                           16    7355
XP_005255374                                                           16    7355
XP_005255373                                                           16    7355
XP_005263305                                                           16    7355
XP_005263304                                                           16    7355
XP_006714389                                                           16    7355
XP_005263303                                                           16    7355
XP_005263302                                                           16    7355
XP_005262723                                                           16    7355
XP_005262722                                                           16    7355
XP_006714091                                                           16    7355
XP_005262720                                                           16    7355
XP_005262719                                                           16    7355
NP_001013009                                                           16    7355
NP_065783                                                              15    9605
NP_059989                                                              15    9605
NP_001010870                                                           15    9605
NP_001161831                                                           15    9605
NP_055554                                                              15    9605
NP_001059                                                              15    9605
NP_060104                                                              15    9605
XP_005273602                                                           15    9605
XP_005273601                                                           15    9605
XP_005273600                                                           15    9605
XP_005273599                                                           15    9605
XP_005273598                                                           15    9605
XP_005267295                                                           15    9605
XP_005267294                                                           15    9605
XP_005267293                                                           15    9605
XP_006715590                                                           15    9605
XP_005267126                                                           15    9605
XP_006715589                                                           15    9605
XP_006715588                                                           15    9605
XP_006715587                                                           15    9605
XP_006715586                                                           15    9605
XP_005265484                                                           15    9605
NP_001070908                                                           15    9605
>NP_000213
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>NP_001087241
          Length = 972

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>XP_006714101
          Length = 526

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>XP_005265799
          Length = 973

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>XP_005265798
          Length = 976

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>XP_005265797
          Length = 977

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKIFLVDRS 9
           AK+FLVDRS
Sbjct: 115 AKLFLVDRS 123
>NP_001034589
          Length = 1215

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IFLVDRS 9
           IFL+DRS
Sbjct: 363 IFLIDRS 369
>XP_006710423
          Length = 932

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  IFLVDRS 9
          IFL+DRS
Sbjct: 80 IFLIDRS 86
>NP_689500
          Length = 539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KIFLVDR 8
           K+F++DR
Sbjct: 399 KVFMIDR 405
>NP_055437
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IFLVDRS 9
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_001106997
          Length = 614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KIFLVDR 8
           K+F++DR
Sbjct: 474 KVFMIDR 480
>NP_938057
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IFLVDRS 9
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>XP_005256385
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KIFLVDR 8
           K+F++DR
Sbjct: 260 KVFMIDR 266
>XP_006721400
          Length = 539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KIFLVDR 8
           K+F++DR
Sbjct: 399 KVFMIDR 405
>XP_005256381
          Length = 597

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   KIFLVDR 8
           K+F++DR
Sbjct: 457 KVFMIDR 463
>NP_001123614
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   IFLVDRS 9
           IFL+DRS
Sbjct: 283 IFLMDRS 289
>NP_001240813
          Length = 1166

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AKIFLVDR 8
          A +FLVDR
Sbjct: 31 AIVFLVDR 38
>NP_803876
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           A+IFL+D+
Sbjct: 265 ARIFLMDK 272
>NP_001257321
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           A+IFL+D+
Sbjct: 253 ARIFLMDK 260
>NP_001257320
          Length = 303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           A+IFL+D+
Sbjct: 231 ARIFLMDK 238
>NP_958834
          Length = 369

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           A+IFL+D+
Sbjct: 297 ARIFLMDK 304
>NP_003254
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_079420
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AKIFLVDR 8
           A +FLVDR
Sbjct: 109 AIVFLVDR 116
>NP_001095876
          Length = 1244

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AKIFLVDR 8
           A +FLVDR
Sbjct: 109 AIVFLVDR 116
>XP_006721109
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIFLVDRS 9
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>XP_005255374
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIFLVDRS 9
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>XP_005255373
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIFLVDRS 9
           KIF +DR+
Sbjct: 503 KIFYIDRN 510
>XP_005263305
          Length = 1167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AKIFLVDR 8
          A +FLVDR
Sbjct: 31 AIVFLVDR 38
>XP_005263304
          Length = 1167

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AKIFLVDR 8
          A +FLVDR
Sbjct: 31 AIVFLVDR 38
>XP_006714389
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AKIFLVDR 8
           A +FLVDR
Sbjct: 109 AIVFLVDR 116
>XP_005263303
          Length = 1245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AKIFLVDR 8
           A +FLVDR
Sbjct: 109 AIVFLVDR 116
>XP_005263302
          Length = 1245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AKIFLVDR 8
           A +FLVDR
Sbjct: 109 AIVFLVDR 116
>XP_005262723
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262722
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_006714091
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262720
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>XP_005262719
          Length = 786

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FLVDRS
Sbjct: 27 FLVDRS 32
>NP_001013009
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIFLVDRS 9
           KIF +DR+
Sbjct: 442 KIFYIDRN 449
>NP_065783
          Length = 2249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1797 LFVVDRS 1803
>NP_059989
          Length = 2236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1784 LFVVDRS 1790
>NP_001010870
          Length = 2096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IFLVDR 8
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_001161831
          Length = 2066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   IFLVDR 8
           +FLVDR
Sbjct: 567 VFLVDR 572
>NP_055554
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           +++FL+DR
Sbjct: 345 SRVFLLDR 352
>NP_001059
          Length = 1621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KIFLVDRS 9
           +IF+VDR+
Sbjct: 928 EIFVVDRN 935
>NP_060104
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   FLVDRS 9
           FL+DRS
Sbjct: 136 FLIDRS 141
>XP_005273602
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273601
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273600
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273599
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005273598
          Length = 275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  FLVDRS 9
          FL+DRS
Sbjct: 22 FLIDRS 27
>XP_005267295
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           +++FL+DR
Sbjct: 345 SRVFLLDR 352
>XP_005267294
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           +++FL+DR
Sbjct: 345 SRVFLLDR 352
>XP_005267293
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           +++FL+DR
Sbjct: 343 SRVFLLDR 350
>XP_006715590
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1825 LFVVDRS 1831
>XP_005267126
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1864 LFVVDRS 1870
>XP_006715589
          Length = 2320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1868 LFVVDRS 1874
>XP_006715588
          Length = 2330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1878 LFVVDRS 1884
>XP_006715587
          Length = 2359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1907 LFVVDRS 1913
>XP_006715586
          Length = 2373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    IFLVDRS 9
            +F+VDRS
Sbjct: 1921 LFVVDRS 1927
>XP_005265484
          Length = 1626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   KIFLVDRS 9
           +IF+VDR+
Sbjct: 933 EIFVVDRN 940
>NP_001070908
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AKIFLVDR 8
           +++FL+DR
Sbjct: 343 SRVFLLDR 350
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.146    0.381 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,862
Number of extensions: 613
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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