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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     869
XP_005273257                                                           19     869
NP_060500                                                              17    4312
NP_001229437                                                           17    4312
NP_542164                                                              17    4312
NP_001273553                                                           17    4312
NP_001273548                                                           17    4312
NP_064537                                                              17    4312
NP_001273563                                                           17    4312
NP_001273547                                                           17    4312
NP_001273546                                                           17    4312
NP_001273551                                                           17    4312
NP_001273549                                                           17    4312
XP_006722446                                                           17    4312
XP_006722445                                                           17    4312
XP_006722444                                                           17    4312
XP_006722443                                                           17    4312
XP_006712843                                                           16    5631
XP_005264079                                                           16    5631
XP_005254804                                                           16    7355
XP_006720791                                                           16    7355
XP_005254803                                                           16    7355
XP_005254800                                                           16    7355
XP_005254799                                                           16    7355
NP_003913                                                              16    7355
NP_000032                                                              15    9605
NP_115627                                                              15    9605
NP_001258029                                                           15    9605
NP_001129505                                                           15    9605
NP_055096                                                              15    9605
NP_510965                                                              15    9605
NP_001258028                                                           15    9605
NP_001258026                                                           15    9605
NP_001660                                                              15    9605
NP_001258025                                                           15    9605
NP_001258027                                                           15    9605
XP_005274573                                                           15    9605
XP_005274572                                                           15    9605
XP_005274571                                                           15    9605
XP_005258924                                                           15    9605
XP_005268640                                                           15    9605
XP_006718583                                                           15    9605
XP_006718582                                                           15    9605
XP_006712788                                                           15    9605
XP_006712786                                                           15    9605
NP_006829                                                              15    9605
NP_001254479                                                           15    9605

>NP_064450
          Length = 1722

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AKIDQAAEE 9
            AKIDQ AEE
Sbjct: 1620 AKIDQEAEE 1628



>XP_005273257
          Length = 1726

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AKIDQAAEE 9
            AKIDQ AEE
Sbjct: 1624 AKIDQEAEE 1632



>NP_060500
          Length = 437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 372 EIDQASEE 379



>NP_001229437
          Length = 568

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 503 EIDQASEE 510



>NP_542164
          Length = 950

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 885 EIDQASEE 892



>NP_001273553
          Length = 87

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 33 AKLDQAEKE 41



>NP_001273548
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 88 AKLDQAEKE 96



>NP_064537
          Length = 242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AKIDQAAEE 9
           AK+DQA +E
Sbjct: 188 AKLDQAEKE 196



>NP_001273563
          Length = 242

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AKIDQAAEE 9
           AK+DQA +E
Sbjct: 188 AKLDQAEKE 196



>NP_001273547
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 88 AKLDQAEKE 96



>NP_001273546
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 88 AKLDQAEKE 96



>NP_001273551
          Length = 136

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 82 AKLDQAEKE 90



>NP_001273549
          Length = 142

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AKIDQAAEE 9
          AK+DQA +E
Sbjct: 88 AKLDQAEKE 96



>XP_006722446
          Length = 889

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 824 EIDQASEE 831



>XP_006722445
          Length = 905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 840 EIDQASEE 847



>XP_006722444
          Length = 914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 849 EIDQASEE 856



>XP_006722443
          Length = 925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KIDQAAEE 9
           +IDQA+EE
Sbjct: 860 EIDQASEE 867



>XP_006712843
          Length = 891

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KIDQAAEE 9
           KIDQ AE+
Sbjct: 112 KIDQLAEQ 119



>XP_005264079
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KIDQAAEE 9
           KIDQ AE+
Sbjct: 107 KIDQLAEQ 114



>XP_005254804
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2551 EIDQQAEE 2558



>XP_006720791
          Length = 4853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2608 EIDQQAEE 2615



>XP_005254803
          Length = 4854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2616 EIDQQAEE 2623



>XP_005254800
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2616 EIDQQAEE 2623



>XP_005254799
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2616 EIDQQAEE 2623



>NP_003913
          Length = 4861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KIDQAAEE 9
            +IDQ AEE
Sbjct: 2616 EIDQQAEE 2623



>NP_000032
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AKIDQAAE 8
          AK++QA E
Sbjct: 18 AKVEQAVE 25



>NP_115627
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIDQAAEE 9
           ++DQ AEE
Sbjct: 411 QVDQLAEE 418



>NP_001258029
          Length = 499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 155 IDQLAEE 161



>NP_001129505
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 172 IDQLAEE 178



>NP_055096
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 198 IDQLAEE 204



>NP_510965
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 215 IDQLAEE 221



>NP_001258028
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 186 IDQLAEE 192



>NP_001258026
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 169 IDQLAEE 175



>NP_001660
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  IDQAAEE 9
          IDQ AEE
Sbjct: 69 IDQLAEE 75



>NP_001258025
          Length = 541

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 197 IDQLAEE 203



>NP_001258027
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IDQAAEE 9
           IDQ AEE
Sbjct: 214 IDQLAEE 220



>XP_005274573
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  IDQAAEE 9
          IDQ AEE
Sbjct: 69 IDQLAEE 75



>XP_005274572
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  IDQAAEE 9
          IDQ AEE
Sbjct: 69 IDQLAEE 75



>XP_005274571
          Length = 548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  IDQAAEE 9
          IDQ AEE
Sbjct: 69 IDQLAEE 75



>XP_005258924
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AKIDQAAE 8
          AK++QA E
Sbjct: 44 AKVEQAVE 51



>XP_005268640
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IDQAAEE 9
           +DQA+EE
Sbjct: 157 LDQASEE 163



>XP_006718583
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIDQAAEE 9
           ++DQ AEE
Sbjct: 333 QVDQLAEE 340



>XP_006718582
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KIDQAAEE 9
           ++DQ AEE
Sbjct: 411 QVDQLAEE 418



>XP_006712788
          Length = 24022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AKIDQAAEE 9
           AK+ +AA+E
Sbjct: 321 AKVPEAAQE 329




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AKIDQAAEE 9
           AK+ +AA+E
Sbjct: 572 AKVPEAAQE 580




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AKIDQAAEE 9
           AK+ +AA+E
Sbjct: 823 AKVPEAAQE 831



>XP_006712786
          Length = 35484

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 11783 AKVPEAAQE 11791




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 12034 AKVPEAAQE 12042




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 12285 AKVPEAAQE 12293



>NP_006829
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   IDQAAEE 9
           +DQA+EE
Sbjct: 158 LDQASEE 164



>NP_001254479
          Length = 35991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 12290 AKVPEAAQE 12298




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 12541 AKVPEAAQE 12549




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1     AKIDQAAEE 9
             AK+ +AA+E
Sbjct: 12792 AKVPEAAQE 12800



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.292    0.110    0.249 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,500
Number of extensions: 513
Number of successful extensions: 53
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)