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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              21     229
NP_055455                                                              17    3301
XP_006712938                                                           17    3301
XP_006712937                                                           17    3301
XP_006712936                                                           17    3301
XP_005247034                                                           17    3301
NP_002086                                                              16    5631
NP_001159530                                                           16    5631
NP_001181966                                                           16    5631
NP_001071174                                                           16    5631
NP_570718                                                              16    5631
XP_006715535                                                           16    5631
NP_000303                                                              16    7355
NP_056280                                                              16    7355
NP_064597                                                              16    7355
NP_001239085                                                           16    7355
XP_006720680                                                           16    7355
XP_006720679                                                           16    7355
XP_006720678                                                           16    7355
XP_006720677                                                           16    7355
XP_006717367                                                           16    7355
XP_006712696                                                           16    7355
XP_005263774                                                           16    7355
XP_005263773                                                           16    7355
XP_005263772                                                           16    7355
NP_660159                                                              15    9605
NP_003882                                                              15    9605
NP_001243063                                                           15    9605
NP_064505                                                              15    9605
XP_006715412                                                           15    9605
XP_006712699                                                           15    9605
XP_006712698                                                           15    9605
XP_006712697                                                           15    9605

>NP_002430
          Length = 1137

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AKGYKMGVV 9
           AKGYK+GVV
Sbjct: 299 AKGYKVGVV 307



>NP_055455
          Length = 1199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KGYKMGVV 9
            KG+ MGVV
Sbjct: 1073 KGFHMGVV 1080



>XP_006712938
          Length = 1138

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KGYKMGVV 9
            KG+ MGVV
Sbjct: 1073 KGFHMGVV 1080



>XP_006712937
          Length = 1199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KGYKMGVV 9
            KG+ MGVV
Sbjct: 1073 KGFHMGVV 1080



>XP_006712936
          Length = 1199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KGYKMGVV 9
            KG+ MGVV
Sbjct: 1073 KGFHMGVV 1080



>XP_005247034
          Length = 1199

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    KGYKMGVV 9
            KG+ MGVV
Sbjct: 1073 KGFHMGVV 1080



>NP_002086
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AKGYKMGVV 9
          + GYK GV+
Sbjct: 70 SSGYKFGVL 78



>NP_001159530
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           +KGY +G+
Sbjct: 562 SKGYSLGI 569



>NP_001181966
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KGYKMGV 8
           +GYK+GV
Sbjct: 356 QGYKIGV 362



>NP_001071174
          Length = 904

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KGYKMGV 8
           +GYK+GV
Sbjct: 356 QGYKIGV 362



>NP_570718
          Length = 754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           +KGY +G+
Sbjct: 586 SKGYSLGI 593



>XP_006715535
          Length = 946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KGYKMGV 8
           +GYK+GV
Sbjct: 356 QGYKIGV 362



>NP_000303
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   AKGYKMG 7
           A GYK+G
Sbjct: 163 APGYKLG 169



>NP_056280
          Length = 1508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AKGYKMGVV 9
           A GYK G+V
Sbjct: 168 AIGYKDGIV 176



>NP_064597
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           AKG+ +GV
Sbjct: 442 AKGFPLGV 449



>NP_001239085
          Length = 1507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AKGYKMGVV 9
           A GYK G+V
Sbjct: 168 AIGYKDGIV 176



>XP_006720680
          Length = 608

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           AKG+ +GV
Sbjct: 442 AKGFPLGV 449



>XP_006720679
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           AKG+ +GV
Sbjct: 442 AKGFPLGV 449



>XP_006720678
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           AKG+ +GV
Sbjct: 413 AKGFPLGV 420



>XP_006720677
          Length = 725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AKGYKMGV 8
           AKG+ +GV
Sbjct: 442 AKGFPLGV 449



>XP_006717367
          Length = 564

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AKGYKM 6
           AKGYK+
Sbjct: 363 AKGYKL 368



>XP_006712696
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   AKGYKMG 7
           A GYK+G
Sbjct: 171 APGYKLG 177



>XP_005263774
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   AKGYKMG 7
           A GYK+G
Sbjct: 184 APGYKLG 190



>XP_005263773
          Length = 516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   AKGYKMG 7
           A GYK+G
Sbjct: 218 APGYKLG 224



>XP_005263772
          Length = 522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   AKGYKMG 7
           A GYK+G
Sbjct: 224 APGYKLG 230



>NP_660159
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 3  GYKMGVV 9
          GY++G++
Sbjct: 55 GYELGII 61



>NP_003882
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   AKGYKMG 7
           A+GY++G
Sbjct: 153 AQGYRLG 159



>NP_001243063
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   AKGYKMG 7
           A+GY++G
Sbjct: 175 AQGYRLG 181



>NP_064505
          Length = 1555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  YKMGVV 9
          YKMGV+
Sbjct: 23 YKMGVL 28



>XP_006715412
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 7/7 (100%)

Query: 3  GYKMGVV 9
          GY++G++
Sbjct: 55 GYELGII 61



>XP_006712699
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  YKMGVV 9
          YKMGV+
Sbjct: 12 YKMGVL 17



>XP_006712698
          Length = 1547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  YKMGVV 9
          YKMGV+
Sbjct: 23 YKMGVL 28



>XP_006712697
          Length = 1549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  YKMGVV 9
          YKMGV+
Sbjct: 17 YKMGVL 22



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.138    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 544,504
Number of extensions: 919
Number of successful extensions: 33
Number of sequences better than 10000.0: 33
Number of HSP's gapped: 33
Number of HSP's successfully gapped: 33
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)