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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              18    1135
NP_079406                                                              17    4312
NP_085146                                                              16    5631
NP_061187                                                              16    5631
NP_663693                                                              16    5631
NP_001073953                                                           16    7355
NP_056448                                                              16    7355
NP_001165358                                                           16    7355
NP_055620                                                              16    7355
NP_001165359                                                           16    7355
XP_005257362                                                           16    7355
XP_006711061                                                           16    7355
XP_006711060                                                           16    7355
XP_005244868                                                           16    7355
NP_861455                                                              16    7355
NP_005262                                                              15    9605
NP_001460                                                              15    9605
NP_001275906                                                           15    9605
NP_001275905                                                           15    9605
NP_001275907                                                           15    9605
NP_000180                                                              15    9605
NP_057554                                                              15    9605
XP_006723866                                                           15    9605
XP_005260482                                                           15    9605
XP_005260481                                                           15    9605
XP_005264337                                                           15    9605

>NP_115803
          Length = 1156

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AIVERLRTR 9
          AIVERLR R
Sbjct: 35 AIVERLRAR 43



>NP_079406
          Length = 917

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   IVERLRTR 9
           I ERLRTR
Sbjct: 771 ISERLRTR 778




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   VERLRT 8
           VERLRT
Sbjct: 403 VERLRT 408



>NP_085146
          Length = 348

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVERLRTR 9
           +VE LRTR
Sbjct: 268 VVETLRTR 275



>NP_061187
          Length = 1133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IVERLRTR 9
          +VERLR R
Sbjct: 73 VVERLRQR 80



>NP_663693
          Length = 351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVERLRTR 9
           +VE LRTR
Sbjct: 271 VVETLRTR 278



>NP_001073953
          Length = 762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VERLRTR 9
           VERLR+R
Sbjct: 492 VERLRSR 498



>NP_056448
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AIVERLR 7
          A+VERLR
Sbjct: 14 ALVERLR 20



>NP_001165358
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AIVERLR 7
          A+VERLR
Sbjct: 14 ALVERLR 20



>NP_055620
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AIVERLR 7
          A+VERLR
Sbjct: 76 ALVERLR 82



>NP_001165359
          Length = 172

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AIVERLR 7
          A+VERLR
Sbjct: 14 ALVERLR 20



>XP_005257362
          Length = 374

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AIVERLRTR 9
           AI+ RLR R
Sbjct: 247 AIIHRLRRR 255



>XP_006711061
          Length = 1553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VERLRTR 9
           VERLR+R
Sbjct: 406 VERLRSR 412



>XP_006711060
          Length = 1595

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VERLRTR 9
           VERLR+R
Sbjct: 448 VERLRSR 454



>XP_005244868
          Length = 1639

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VERLRTR 9
           VERLR+R
Sbjct: 492 VERLRSR 498



>NP_861455
          Length = 462

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AIVERLRTR 9
           AI+ RLR R
Sbjct: 335 AIIHRLRRR 343



>NP_005262
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  IVERLRTR 9
          +VE LRTR
Sbjct: 85 LVEDLRTR 92



>NP_001460
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AIVERLR 7
           AIVE+LR
Sbjct: 464 AIVEKLR 470



>NP_001275906
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AIVERLR 7
           AIVE+LR
Sbjct: 423 AIVEKLR 429



>NP_001275905
          Length = 609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AIVERLR 7
           AIVE+LR
Sbjct: 464 AIVEKLR 470



>NP_001275907
          Length = 559

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AIVERLR 7
           AIVE+LR
Sbjct: 414 AIVEKLR 420



>NP_000180
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVERLRTR 9
           I ERL+TR
Sbjct: 772 ISERLKTR 779



>NP_057554
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AIVERLRT 8
           A+VE LRT
Sbjct: 145 AVVEPLRT 152



>XP_006723866
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AIVERLRT 8
           A+VE LRT
Sbjct: 145 AVVEPLRT 152



>XP_005260482
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AIVERLRT 8
           A+VE LRT
Sbjct: 145 AVVEPLRT 152



>XP_005260481
          Length = 292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AIVERLRT 8
           A+VE LRT
Sbjct: 145 AVVEPLRT 152



>XP_005264337
          Length = 938

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IVERLRTR 9
           I ERL+TR
Sbjct: 793 ISERLKTR 800



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.143    0.355 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 414,668
Number of extensions: 621
Number of successful extensions: 27
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)