Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_056364                                                              18    1482
XP_005267570                                                           18    1482
XP_006720171                                                           18    1482
XP_005267569                                                           18    1482
XP_005267568                                                           18    1482
XP_006720170                                                           18    1482
XP_006720169                                                           18    1482
NP_006209                                                              18    1935
XP_006713721                                                           18    1935
NP_060362                                                              17    4312
XP_005246736                                                           17    4312
XP_005246735                                                           17    4312
XP_005246734                                                           17    4312
XP_005246733                                                           17    4312
NP_003165                                                              16    5631
NP_068506                                                              16    5631
XP_006717559                                                           16    5631
XP_006717558                                                           16    5631
XP_006717557                                                           16    5631
XP_006717556                                                           16    5631
XP_005252630                                                           16    5631
XP_005252629                                                           16    5631
XP_005252628                                                           16    5631
XP_005252627                                                           16    5631
XP_005252626                                                           16    5631
XP_005252625                                                           16    5631
XP_005252624                                                           16    5631
XP_005252623                                                           16    5631
XP_005252622                                                           16    5631
XP_006717555                                                           16    5631
XP_005252621                                                           16    5631
NP_001139280                                                           16    7355
NP_000623                                                              16    7355
NP_005306                                                              16    7355
NP_055945                                                              15    9605
>NP_056364
          Length = 1163

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 652 ALSTRDRL 659
>XP_005267570
          Length = 1219

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 708 ALSTRDRL 715
>XP_006720171
          Length = 1240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 729 ALSTRDRL 736
>XP_005267569
          Length = 1340

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 829 ALSTRDRL 836
>XP_005267568
          Length = 1340

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 829 ALSTRDRL 836
>XP_006720170
          Length = 1354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 843 ALSTRDRL 850
>XP_006720169
          Length = 1361

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           A+STRDRL
Sbjct: 850 ALSTRDRL 857
>NP_006209
          Length = 1068

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISTRDRLS 9
           AISTRD LS
Sbjct: 533 AISTRDPLS 541
>XP_006713721
          Length = 1068

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISTRDRLS 9
           AISTRD LS
Sbjct: 533 AISTRDPLS 541
>NP_060362
          Length = 930

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AISTRDRL 8
           AIS RDRL
Sbjct: 471 AISERDRL 478
>XP_005246736
          Length = 976

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AISTRDRL 8
           AIS RDRL
Sbjct: 513 AISERDRL 520
>XP_005246735
          Length = 976

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AISTRDRL 8
           AIS RDRL
Sbjct: 513 AISERDRL 520
>XP_005246734
          Length = 934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AISTRDRL 8
           AIS RDRL
Sbjct: 471 AISERDRL 478
>XP_005246733
          Length = 972

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AISTRDRL 8
           AIS RDRL
Sbjct: 513 AISERDRL 520
>NP_003165
          Length = 1788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 406 AISTRNRI 413
>NP_068506
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 832 AISTRNRI 839
>XP_006717559
          Length = 1866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 484 AISTRNRI 491
>XP_006717558
          Length = 1908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 484 AISTRNRI 491
>XP_006717557
          Length = 1940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 516 AISTRNRI 523
>XP_006717556
          Length = 2024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 600 AISTRNRI 607
>XP_005252630
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 832 AISTRNRI 839
>XP_005252629
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 832 AISTRNRI 839
>XP_005252628
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 832 AISTRNRI 839
>XP_005252627
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 832 AISTRNRI 839
>XP_005252626
          Length = 2260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 878 AISTRNRI 885
>XP_005252625
          Length = 2277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 853 AISTRNRI 860
>XP_005252624
          Length = 2292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 910 AISTRNRI 917
>XP_005252623
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 878 AISTRNRI 885
>XP_005252622
          Length = 2308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 910 AISTRNRI 917
>XP_006717555
          Length = 2328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 904 AISTRNRI 911
>XP_005252621
          Length = 2334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AISTRDRL 8
           AISTR+R+
Sbjct: 910 AISTRNRI 917
>NP_001139280
          Length = 1153

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STRDRL 8
           STRDRL
Sbjct: 661 STRDRL 666
>NP_000623
          Length = 1152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   STRDRL 8
           STRDRL
Sbjct: 660 STRDRL 665
>NP_005306
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISTRDRLS 9
           +STR+RL+
Sbjct: 153 VSTRERLA 160
>NP_055945
          Length = 1266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AISTRDRLS 9
           +ISTR+R++
Sbjct: 371 SISTRNRMT 379
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.124    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 370,345
Number of extensions: 549
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package