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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              18    1482
NP_434701                                                              18    1482
NP_434700                                                              18    1482
NP_055792                                                              16    7355
NP_001158287                                                           16    7355
NP_001158286                                                           16    7355
NP_001158288                                                           16    7355
NP_001158289                                                           16    7355
XP_005267475                                                           16    7355
XP_005267473                                                           16    7355
XP_005267472                                                           16    7355
NP_004818                                                              15    9605
NP_001244315                                                           15    9605
NP_001276976                                                           15    9605
NP_002843                                                              15    9605
NP_001276975                                                           15    9605
NP_056261                                                              15    9605
NP_001165349                                                           15    9605
NP_001165350                                                           15    9605
NP_005360                                                              15    9605
NP_001165347                                                           15    9605
NP_079143                                                              15    9605
XP_006724820                                                           15    9605
XP_005262471                                                           15    9605
XP_005262470                                                           15    9605
XP_006724141                                                           15    9605
XP_006714564                                                           15    9605
XP_006714563                                                           15    9605
XP_005248434                                                           15    9605
XP_005248433                                                           15    9605
XP_005263413                                                           15    9605
XP_005263412                                                           15    9605
XP_005263411                                                           15    9605
XP_006711822                                                           15    9605
XP_006711821                                                           15    9605
NP_001165348                                                           15    9605
NP_001093325                                                           15    9605

>NP_004351
          Length = 882

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AISTRAEL 8
           AISTRAEL
Sbjct: 541 AISTRAEL 548



>NP_434701
          Length = 492

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AISTRAELH 9
           AI+TR ELH
Sbjct: 360 AIATREELH 368



>NP_434700
          Length = 536

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AISTRAELH 9
           AI+TR ELH
Sbjct: 360 AIATREELH 368



>NP_055792
          Length = 1341

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            A++TR  LH
Sbjct: 1062 AVATRTALH 1070



>NP_001158287
          Length = 1301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            A++TR  LH
Sbjct: 1022 AVATRTALH 1030



>NP_001158286
          Length = 1328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            A++TR  LH
Sbjct: 1049 AVATRTALH 1057



>NP_001158288
          Length = 614

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A++TR  LH
Sbjct: 335 AVATRTALH 343



>NP_001158289
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A++TR  LH
Sbjct: 304 AVATRTALH 312



>XP_005267475
          Length = 583

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A++TR  LH
Sbjct: 304 AVATRTALH 312



>XP_005267473
          Length = 1329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            A++TR  LH
Sbjct: 1050 AVATRTALH 1058



>XP_005267472
          Length = 1340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            A++TR  LH
Sbjct: 1061 AVATRTALH 1069



>NP_004818
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 345 TKAELH 350



>NP_001244315
          Length = 611

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 345 TKAELH 350



>NP_001276976
          Length = 1464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 297 TKAELH 302



>NP_002843
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           TRA+LH
Sbjct: 159 TRADLH 164



>NP_001276975
          Length = 1300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 134 TKAELH 139



>NP_056261
          Length = 2275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            AIS  +ELH
Sbjct: 1172 AISRASELH 1180



>NP_001165349
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 171 AVSSRLECH 179



>NP_001165350
          Length = 941

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 171 AVSSRLECH 179



>NP_005360
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 171 AVSSRLECH 179



>NP_001165347
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 231 AVSSRLECH 239



>NP_079143
          Length = 1822

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TRAELH 9
            T+AELH
Sbjct: 1101 TKAELH 1106



>XP_006724820
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 132 AVSSRLECH 140



>XP_005262471
          Length = 1005

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 316 AVSSRLECH 324



>XP_005262470
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 274 AVSSRLECH 282



>XP_006724141
          Length = 1426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 259 TKAELH 264



>XP_006714564
          Length = 1537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TRAELH 9
            T+AELH
Sbjct: 1101 TKAELH 1106



>XP_006714563
          Length = 1766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TRAELH 9
            T+AELH
Sbjct: 1044 TKAELH 1049



>XP_005248434
          Length = 1818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TRAELH 9
            T+AELH
Sbjct: 1096 TKAELH 1101



>XP_005248433
          Length = 1823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    TRAELH 9
            T+AELH
Sbjct: 1101 TKAELH 1106



>XP_005263413
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 343 TKAELH 348



>XP_005263412
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 345 TKAELH 350



>XP_005263411
          Length = 655

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   TRAELH 9
           T+AELH
Sbjct: 345 TKAELH 350



>XP_006711822
          Length = 2266

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            AIS  +ELH
Sbjct: 1163 AISRASELH 1171



>XP_006711821
          Length = 2301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AISTRAELH 9
            AIS  +ELH
Sbjct: 1198 AISRASELH 1206



>NP_001165348
          Length = 821

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 132 AVSSRLECH 140



>NP_001093325
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AISTRAELH 9
           A+S+R E H
Sbjct: 231 AVSSRLECH 239



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.120    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 363,512
Number of extensions: 448
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)