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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           18    1935
NP_858045                                                              18    1935
NP_006525                                                              18    1935
NP_001167559                                                           18    1935
NP_065961                                                              16    5631
NP_001158137                                                           16    5631
XP_006716134                                                           16    5631
XP_005245269                                                           16    5631
XP_006711403                                                           16    5631
NP_653300                                                              16    5631
NP_001019554                                                           16    7355
NP_055718                                                              16    7355
NP_075559                                                              16    7355
XP_006719739                                                           16    7355
XP_006719738                                                           16    7355
XP_005269272                                                           16    7355
NP_444256                                                              15    9605
NP_444254                                                              15    9605
NP_444253                                                              15    9605
NP_444255                                                              15    9605
NP_001164277                                                           15    9605
NP_775820                                                              15    9605
XP_005247551                                                           15    9605
XP_005247550                                                           15    9605
XP_006713712                                                           15    9605
XP_005247549                                                           15    9605
NP_055044                                                              15    9605

>NP_001167558
          Length = 1423

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISEGVETS 9
           AISEGV TS
Sbjct: 528 AISEGVGTS 536



>NP_858045
          Length = 1424

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISEGVETS 9
           AISEGV TS
Sbjct: 528 AISEGVGTS 536



>NP_006525
          Length = 1420

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISEGVETS 9
           AISEGV TS
Sbjct: 528 AISEGVGTS 536



>NP_001167559
          Length = 1415

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AISEGVETS 9
           AISEGV TS
Sbjct: 538 AISEGVGTS 546



>NP_065961
          Length = 1934

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AISEGVETS 9
           +++EGVET+
Sbjct: 272 SLTEGVETT 280



>NP_001158137
          Length = 1950

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AISEGVETS 9
           +++EGVET+
Sbjct: 272 SLTEGVETT 280



>XP_006716134
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AISEGVETS 9
           +++EGVET+
Sbjct: 196 SLTEGVETT 204



>XP_005245269
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ISEGVETS 9
           ISEG ET+
Sbjct: 143 ISEGTETA 150



>XP_006711403
          Length = 961

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ISEGVETS 9
           ISEG ET+
Sbjct: 572 ISEGTETA 579



>NP_653300
          Length = 1029

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ISEGVETS 9
           ISEG ET+
Sbjct: 640 ISEGTETA 647



>NP_001019554
          Length = 2385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISEGVETS 9
           +SEGV+T+
Sbjct: 370 VSEGVKTA 377



>NP_055718
          Length = 2363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISEGVETS 9
           +SEGV+T+
Sbjct: 370 VSEGVKTA 377



>NP_075559
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AISEGVET 8
           ++SEG+ET
Sbjct: 146 SLSEGLET 153



>XP_006719739
          Length = 2306

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISEGVETS 9
           +SEGV+T+
Sbjct: 313 VSEGVKTA 320



>XP_006719738
          Length = 2340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISEGVETS 9
           +SEGV+T+
Sbjct: 347 VSEGVKTA 354



>XP_005269272
          Length = 2356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ISEGVETS 9
           +SEGV+T+
Sbjct: 370 VSEGVKTA 377



>NP_444256
          Length = 1794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1500 ISEGVE 1505



>NP_444254
          Length = 1845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1500 ISEGVE 1505



>NP_444253
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1569 ISEGVE 1574



>NP_444255
          Length = 1863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1569 ISEGVE 1574



>NP_001164277
          Length = 56

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  ISEGVET 8
          +SEG ET
Sbjct: 35 VSEGAET 41



>NP_775820
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   ISEGVET 8
           +SEG ET
Sbjct: 353 VSEGAET 359



>XP_005247551
          Length = 1855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1510 ISEGVE 1515



>XP_005247550
          Length = 1856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1511 ISEGVE 1516



>XP_006713712
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1579 ISEGVE 1584



>XP_005247549
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    ISEGVE 7
            ISEGVE
Sbjct: 1579 ISEGVE 1584



>NP_055044
          Length = 632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AISEGVE 7
           AIS+G+E
Sbjct: 213 AISDGIE 219



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287    0.109    0.246 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 520,369
Number of extensions: 961
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.8 bits)
S2: 28 (15.4 bits)