Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002515                                                              20     509
NP_789765                                                              18    1135
NP_001123914                                                           18    1135
NP_005334                                                              18    1135
NP_004976                                                              18    1135
NP_203524                                                              18    1135
XP_006725199                                                           18    1135
XP_006719132                                                           18    1135
XP_006718280                                                           18    1135
NP_001177645                                                           17    3301
NP_004936                                                              17    3301
NP_001005361                                                           17    3301
NP_001139267                                                           17    3301
NP_001005360                                                           17    3301
NP_001005362                                                           17    3301
NP_001275668                                                           17    4312
NP_004399                                                              17    4312
NP_001275667                                                           17    4312
NP_001005336                                                           17    4312
NP_001275666                                                           17    4312
NP_001269569                                                           17    4312
NP_001269572                                                           17    4312
NP_071931                                                              17    4312
XP_006717057                                                           17    4312
XP_005251826                                                           17    4312
XP_005251825                                                           17    4312
XP_005251821                                                           17    4312
XP_005251820                                                           17    4312
XP_006717055                                                           17    4312
NP_996879                                                              16    5631
XP_005248250                                                           16    5631
XP_006710494                                                           16    5631
XP_006710492                                                           16    5631
XP_006710491                                                           16    5631
XP_006710490                                                           16    5631
XP_006710489                                                           16    5631
NP_444270                                                              16    5631
NP_840060                                                              16    7355
NP_001167543                                                           16    7355
NP_000258                                                              16    7355
NP_001035957                                                           16    7355
NP_001167542                                                           16    7355
NP_078997                                                              16    7355
XP_006721991                                                           16    7355
XP_006721990                                                           16    7355
XP_006721989                                                           16    7355
XP_005258041                                                           16    7355
XP_006721988                                                           16    7355
XP_006721987                                                           16    7355
XP_006721986                                                           16    7355
XP_005258040                                                           16    7355
XP_006721985                                                           16    7355
XP_005248535                                                           16    7355
NP_001136272                                                           15    9605
NP_066270                                                              15    9605
NP_056384                                                              15    9605
NP_001129599                                                           15    9605
NP_001015001                                                           15    9605
XP_005254555                                                           15    9605
XP_005254207                                                           15    9605
XP_005245139                                                           15    9605
XP_005245138                                                           15    9605
XP_005245137                                                           15    9605
XP_005245136                                                           15    9605
>NP_002515
          Length = 189

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINNSKSF
Sbjct: 83 AINNSKSF 90
>NP_789765
          Length = 170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>NP_001123914
          Length = 189

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>NP_005334
          Length = 189

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>NP_004976
          Length = 188

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>NP_203524
          Length = 189

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>XP_006725199
          Length = 170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>XP_006719132
          Length = 189

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>XP_006718280
          Length = 170

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1  AINNSKSF 8
          AINN+KSF
Sbjct: 83 AINNTKSF 90
>NP_001177645
          Length = 869

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INNSKSFV 9
           INN+K+F+
Sbjct: 684 INNTKAFI 691
>NP_004936
          Length = 866

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INNSKSFV 9
           INN+K+F+
Sbjct: 680 INNTKAFI 687
>NP_001005361
          Length = 870

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INNSKSFV 9
           INN+K+F+
Sbjct: 684 INNTKAFI 691
>NP_001139267
          Length = 756

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AINNSKSFV 9
           AINN  SFV
Sbjct: 748 AINNQYSFV 756
>NP_001005360
          Length = 870

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INNSKSFV 9
           INN+K+F+
Sbjct: 684 INNTKAFI 691
>NP_001005362
          Length = 866

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   INNSKSFV 9
           INN+K+F+
Sbjct: 680 INNTKAFI 687
>NP_001275668
          Length = 864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_004399
          Length = 864

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_001275667
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_001005336
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_001275666
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_001269569
          Length = 757

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AINNSKSFV 9
           A NN+K+F+
Sbjct: 108 ATNNNKTFI 116
>NP_001269572
          Length = 722

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AINNSKSFV 9
           A NN+K+F+
Sbjct: 108 ATNNNKTFI 116
>NP_071931
          Length = 747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AINNSKSFV 9
           A NN+K+F+
Sbjct: 108 ATNNNKTFI 116
>XP_006717057
          Length = 867

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>XP_005251826
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>XP_005251825
          Length = 851

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>XP_005251821
          Length = 867

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>XP_005251820
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>XP_006717055
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   INNSKSFV 9
           INN+K F+
Sbjct: 690 INNTKEFI 697
>NP_996879
          Length = 2223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 2065 AINNAKS 2071
>XP_005248250
          Length = 1074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 449 NNGKSFI 455
>XP_006710494
          Length = 1152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 994  AINNAKS 1000
>XP_006710492
          Length = 1351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 1193 AINNAKS 1199
>XP_006710491
          Length = 1496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 1338 AINNAKS 1344
>XP_006710490
          Length = 2158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 2000 AINNAKS 2006
>XP_006710489
          Length = 2185

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AINNSKS 7
            AINN+KS
Sbjct: 2027 AINNAKS 2033
>NP_444270
          Length = 1074

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 449 NNGKSFI 455
>NP_840060
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   INNSKS 7
           INNSKS
Sbjct: 112 INNSKS 117
>NP_001167543
          Length = 461

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   INNSKS 7
           INNSKS
Sbjct: 112 INNSKS 117
>NP_000258
          Length = 2818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1470 AVNHSLSFI 1478
>NP_001035957
          Length = 2839

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1491 AVNHSLSFI 1499
>NP_001167542
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   INNSKS 7
           INNSKS
Sbjct: 112 INNSKS 117
>NP_078997
          Length = 3616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    AINNSKSF 8
            A+N+ KSF
Sbjct: 3418 AVNHQKSF 3425
>XP_006721991
          Length = 1632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1501 AVNHSLSFI 1509
>XP_006721990
          Length = 2823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1501 AVNHSLSFI 1509
>XP_006721989
          Length = 2823

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1501 AVNHSLSFI 1509
>XP_005258041
          Length = 2836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1470 AVNHSLSFI 1478
>XP_006721988
          Length = 2846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1480 AVNHSLSFI 1488
>XP_006721987
          Length = 2849

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1501 AVNHSLSFI 1509
>XP_006721986
          Length = 2854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1488 AVNHSLSFI 1496
>XP_005258040
          Length = 2857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1491 AVNHSLSFI 1499
>XP_006721985
          Length = 2867

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AINNSKSFV 9
            A+N+S SF+
Sbjct: 1501 AVNHSLSFI 1509
>XP_005248535
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  INNSKS 7
          INNSKS
Sbjct: 41 INNSKS 46
>NP_001136272
          Length = 3144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    INNSKSFV 9
            INN +SF+
Sbjct: 2043 INNWRSFI 2050
>NP_066270
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 253 NNEKSFL 259
>NP_056384
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 684 INNVKDFI 691
>NP_001129599
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 680 INNVKDFI 687
>NP_001015001
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 253 NNEKSFL 259
>XP_005254555
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 94  NNEKSFL 100
>XP_005254207
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   NNSKSFV 9
           NN KSF+
Sbjct: 94  NNEKSFL 100
>XP_005245139
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 584 INNVKDFI 591
>XP_005245138
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 694 INNVKDFI 701
>XP_005245137
          Length = 869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 690 INNVKDFI 697
>XP_005245136
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   INNSKSFV 9
           INN K F+
Sbjct: 694 INNVKDFI 701
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.119    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 420,930
Number of extensions: 648
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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