Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001167558                                                           19     869
NP_858045                                                              19     869
NP_006525                                                              19     869
NP_001167559                                                           19     869
NP_001128472                                                           17    4312
NP_002261                                                              17    4312
NP_694858                                                              17    4312
NP_001128471                                                           17    4312
NP_006823                                                              17    4312
NP_001129668                                                           17    4312
NP_001129667                                                           17    4312
NP_038461                                                              17    4312
XP_005267342                                                           17    4312
XP_006720073                                                           17    4312
XP_006720072                                                           17    4312
XP_006720071                                                           17    4312
XP_005248557                                                           17    4312
XP_005248558                                                           17    4312
NP_004303                                                              16    5631
NP_079350                                                              16    5631
XP_006724714                                                           16    5631
XP_006714380                                                           16    5631
XP_006714379                                                           16    5631
XP_006714378                                                           16    5631
XP_006714377                                                           16    5631
NP_000177                                                              16    7355
NP_002104                                                              16    7355
NP_078966                                                              16    7355
NP_005657                                                              16    7355
NP_001135451                                                           16    7355
NP_005648                                                              16    7355
NP_001135452                                                           16    7355
NP_055811                                                              16    7355
XP_006720729                                                           16    7355
XP_005254692                                                           16    7355
XP_005254691                                                           16    7355
XP_005247296                                                           16    7355
XP_006713604                                                           16    7355
XP_005247295                                                           16    7355
XP_005245170                                                           16    7355
XP_006711348                                                           16    7355
XP_006711347                                                           16    7355
XP_006711345                                                           16    7355
NP_001124432                                                           16    7355
NP_001123473                                                           15    9605
NP_001123474                                                           15    9605
NP_057311                                                              15    9605
NP_055098                                                              15    9605
NP_001093247                                                           15    9605
NP_542376                                                              15    9605
NP_004361                                                              15    9605
NP_001230658                                                           15    9605
NP_872413                                                              15    9605
NP_001269680                                                           15    9605
XP_005262184                                                           15    9605
XP_005268677                                                           15    9605
XP_006719281                                                           15    9605
XP_006719280                                                           15    9605
XP_005268675                                                           15    9605
XP_005268674                                                           15    9605
XP_006715397                                                           15    9605
XP_005247199                                                           15    9605
XP_005245308                                                           15    9605
XP_006711439                                                           15    9605
XP_006711438                                                           15    9605
XP_006711437                                                           15    9605
NP_001164024                                                           15    9605
NP_443129                                                              15    9605
>NP_001167558
          Length = 1423

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           AILGDLTS
Sbjct: 802 AILGDLTS 809
>NP_858045
          Length = 1424

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           AILGDLTS
Sbjct: 802 AILGDLTS 809
>NP_006525
          Length = 1420

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           AILGDLTS
Sbjct: 802 AILGDLTS 809
>NP_001167559
          Length = 1415

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           AILGDLTS
Sbjct: 812 AILGDLTS 819
>NP_001128472
          Length = 633

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 365 ILGDITS 371
>NP_002261
          Length = 898

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 697 ALLGDLT 703
>NP_694858
          Length = 890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 689 ALLGDLT 695
>NP_001128471
          Length = 687

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 365 ILGDITS 371
>NP_006823
          Length = 680

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 365 ILGDITS 371
>NP_001129668
          Length = 897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 686 ALLGDLT 692
>NP_001129667
          Length = 887

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 686 ALLGDLT 692
>NP_038461
          Length = 887

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 686 ALLGDLT 692
>XP_005267342
          Length = 691

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 376 ILGDITS 382
>XP_006720073
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 365 ILGDITS 371
>XP_006720072
          Length = 698

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 376 ILGDITS 382
>XP_006720071
          Length = 706

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGD+TS
Sbjct: 376 ILGDITS 382
>XP_005248557
          Length = 890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 689 ALLGDLT 695
>XP_005248558
          Length = 866

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILGDLT 7
           A+LGDLT
Sbjct: 697 ALLGDLT 703
>NP_004303
          Length = 388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGDLT+
Sbjct: 331 ILGDLTA 337
>NP_079350
          Length = 4012

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AILGDLTS 8
            A+LGD+T+
Sbjct: 3140 AVLGDVTT 3147
>XP_006724714
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           ILGDLT+
Sbjct: 286 ILGDLTA 292
>XP_006714380
          Length = 3897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AILGDLTS 8
            A+LGD+T+
Sbjct: 3025 AVLGDVTT 3032
>XP_006714379
          Length = 3936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AILGDLTS 8
            A+LGD+T+
Sbjct: 3064 AVLGDVTT 3071
>XP_006714378
          Length = 3965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AILGDLTS 8
            A+LGD+T+
Sbjct: 3093 AVLGDVTT 3100
>XP_006714377
          Length = 4010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AILGDLTS 8
            A+LGD+T+
Sbjct: 3138 AVLGDVTT 3145
>NP_000177
          Length = 1231

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GDLTSF 9
            GD+TSF
Sbjct: 1118 GDITSF 1123
>NP_002104
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GDLTSF 9
           GD+TSF
Sbjct: 217 GDITSF 222
>NP_078966
          Length = 14507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    ILGDLTS 8
            I+GD+TS
Sbjct: 4280 IMGDITS 4286
>NP_005657
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GDLTSF 9
           GD+TSF
Sbjct: 158 GDITSF 163
>NP_001135451
          Length = 1975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LGDLTSF 9
            LGD++SF
Sbjct: 1304 LGDISSF 1310
>NP_005648
          Length = 1972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LGDLTSF 9
            LGD++SF
Sbjct: 1299 LGDISSF 1305
>NP_001135452
          Length = 1977

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LGDLTSF 9
            LGD++SF
Sbjct: 1304 LGDISSF 1310
>NP_055811
          Length = 1655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LGDLTS 8
            LGDLTS
Sbjct: 1457 LGDLTS 1462
>XP_006720729
          Length = 940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGDLTSF 9
           LGD++SF
Sbjct: 267 LGDISSF 273
>XP_005254692
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGDLTSF 9
           LGD++SF
Sbjct: 344 LGDISSF 350
>XP_005254691
          Length = 1972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LGDLTSF 9
            LGD++SF
Sbjct: 1299 LGDISSF 1305
>XP_005247296
          Length = 1673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LGDLTS 8
            LGDLTS
Sbjct: 1475 LGDLTS 1480
>XP_006713604
          Length = 1685

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LGDLTS 8
            LGDLTS
Sbjct: 1487 LGDLTS 1492
>XP_005247295
          Length = 1705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LGDLTS 8
            LGDLTS
Sbjct: 1507 LGDLTS 1512
>XP_005245170
          Length = 205

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GD+TSF
Sbjct: 93 GDITSF 98
>XP_006711348
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GDLTSF 9
           GD+TSF
Sbjct: 104 GDITSF 109
>XP_006711347
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   GDLTSF 9
           GD+TSF
Sbjct: 163 GDITSF 168
>XP_006711345
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    GDLTSF 9
            GD+TSF
Sbjct: 1060 GDITSF 1065
>NP_001124432
          Length = 1693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    LGDLTS 8
            LGDLTS
Sbjct: 1495 LGDLTS 1500
>NP_001123473
          Length = 133

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GDLT+F
Sbjct: 54 GDLTNF 59
>NP_001123474
          Length = 135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GDLT+F
Sbjct: 54 GDLTNF 59
>NP_057311
          Length = 1405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 849 VLGDLSS 855
>NP_055098
          Length = 1254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 698 VLGDLSS 704
>NP_001093247
          Length = 118

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GDLT+F
Sbjct: 54 GDLTNF 59
>NP_542376
          Length = 1899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AILGDLTS 8
           A+L DLTS
Sbjct: 383 AVLHDLTS 390
>NP_004361
          Length = 3063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AILGDLTS 8
            A+L DLTS
Sbjct: 1547 AVLHDLTS 1554
>NP_001230658
          Length = 72

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GDLT+F
Sbjct: 54 GDLTNF 59
>NP_872413
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ILGDLTSF 9
           ++G+LT+F
Sbjct: 197 VIGNLTNF 204
>NP_001269680
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 135 VLGDLSS 141
>XP_005262184
          Length = 449

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ILGDLTSF 9
           ++G+LT+F
Sbjct: 259 VIGNLTNF 266
>XP_005268677
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
>XP_006719281
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
>XP_006719280
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
>XP_005268675
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
>XP_005268674
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
>XP_006715397
          Length = 2972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AILGDLTS 8
            A+L DLTS
Sbjct: 1456 AVLHDLTS 1463
>XP_005247199
          Length = 89

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  GDLTSF 9
          GDLT+F
Sbjct: 54 GDLTNF 59
>XP_005245308
          Length = 1092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 698 VLGDLSS 704
>XP_006711439
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 654 VLGDLSS 660
>XP_006711438
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 661 VLGDLSS 667
>XP_006711437
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILGDLTS 8
           +LGDL+S
Sbjct: 691 VLGDLSS 697
>NP_001164024
          Length = 423

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ILGDLTSF 9
           ++G+LT+F
Sbjct: 233 VIGNLTNF 240
>NP_443129
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AILGDLTS 8
           ++LGDL+S
Sbjct: 743 SLLGDLSS 750
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.146    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 455,876
Number of extensions: 670
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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