Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_004786                                                              17    4312
NP_001264044                                                           17    4312
NP_001363                                                              17    4312
NP_775899                                                              17    4312
NP_004653                                                              17    4312
NP_997715                                                              16    5631
NP_065681                                                              16    5631
NP_066124                                                              16    5631
NP_063939                                                              16    5631
XP_006717999                                                           16    5631
NP_689837                                                              16    7355
NP_001229306                                                           16    7355
NP_597713                                                              16    7355
NP_001273661                                                           16    7355
NP_001166171                                                           16    7355
NP_078995                                                              16    7355
NP_001273662                                                           16    7355
XP_006720043                                                           16    7355
XP_006720042                                                           16    7355
XP_005268391                                                           16    7355
XP_005268390                                                           16    7355
XP_005271971                                                           16    7355
XP_005271944                                                           16    7355
XP_005271943                                                           16    7355
XP_006714596                                                           16    7355
XP_005271942                                                           16    7355
NP_001271271                                                           15    9605
NP_001231879                                                           15    9605
NP_055582                                                              15    9605
NP_056505                                                              15    9605
NP_001177925                                                           15    9605
NP_006400                                                              15    9605
NP_005190                                                              15    9605
NP_001230242                                                           15    9605
NP_055670                                                              15    9605
NP_005711                                                              15    9605
XP_006715889                                                           15    9605
XP_006715888                                                           15    9605
XP_006712484                                                           15    9605
XP_006712483                                                           15    9605
XP_005246521                                                           15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A NVLLAQG
Sbjct: 821 ARNVLLAQG 829
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A NVLLAQG
Sbjct: 821 ARNVLLAQG 829
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A NVLLAQG
Sbjct: 843 ARNVLLAQG 851
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A NVLLAQG
Sbjct: 846 ARNVLLAQG 854
>NP_004786
          Length = 1012

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AHNVLLA 7
           AHN+LLA
Sbjct: 268 AHNLLLA 274
>NP_001264044
          Length = 4516

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    HNVLLAQG 9
            HNV L QG
Sbjct: 3960 HNVSLGQG 3967
>NP_001363
          Length = 4486

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    HNVLLAQG 9
            HNV L QG
Sbjct: 3930 HNVSLGQG 3937
>NP_775899
          Length = 4462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    HNVLLAQG 9
            HNV L QG
Sbjct: 3906 HNVSLGQG 3913
>NP_004653
          Length = 798

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   HNVLLAQG 9
           HNV L QG
Sbjct: 242 HNVSLGQG 249
>NP_997715
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           AH+V LA+G
Sbjct: 157 AHSVRLARG 165
>NP_065681
          Length = 1072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A N+L+A+G
Sbjct: 877 ARNILVAEG 885
>NP_066124
          Length = 1114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A N+L+A+G
Sbjct: 877 ARNILVAEG 885
>NP_063939
          Length = 486

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   HNVLLAQG 9
           H VLLA G
Sbjct: 312 HRVLLAHG 319
>XP_006717999
          Length = 1207

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AHNVLLAQG 9
           A N+L+A+G
Sbjct: 970 ARNILVAEG 978
>NP_689837
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NVLLAQG 9
           NVLL QG
Sbjct: 111 NVLLVQG 117
>NP_001229306
          Length = 385

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NVLLAQG 9
           NVLL QG
Sbjct: 111 NVLLVQG 117
>NP_597713
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>NP_001273661
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 138 YNVLLAYG 145
>NP_001166171
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>NP_078995
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 138 YNVLLAYG 145
>NP_001273662
          Length = 236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 138 YNVLLAYG 145
>XP_006720043
          Length = 190

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 138 YNVLLAYG 145
>XP_006720042
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  HNVLLAQG 9
          +NVLLA G
Sbjct: 35 YNVLLAYG 42
>XP_005268391
          Length = 266

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  HNVLLAQG 9
          +NVLLA G
Sbjct: 60 YNVLLAYG 67
>XP_005268390
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  HNVLLAQG 9
          +NVLLA G
Sbjct: 85 YNVLLAYG 92
>XP_005271971
          Length = 272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   NVLLAQG 9
           NVLL QG
Sbjct: 111 NVLLVQG 117
>XP_005271944
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>XP_005271943
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>XP_006714596
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>XP_005271942
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AHNVLLAQG 9
           +HN  LA+G
Sbjct: 519 SHNTALARG 527
>NP_001271271
          Length = 177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           H+VL A+G
Sbjct: 93  HSVLCAEG 100
>NP_001231879
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   HNVLLAQG 9
           H V +AQG
Sbjct: 98  HKVCIAQG 105
>NP_055582
          Length = 424

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   HNVLLAQG 9
           H V +AQG
Sbjct: 98  HKVCIAQG 105
>NP_056505
          Length = 1315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           N+LLA+G
Sbjct: 130 NILLAKG 136
>NP_001177925
          Length = 356

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 139 NNVLLAAG 146
>NP_006400
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 153 NNVLLAAG 160
>NP_005190
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AHNVLLAQ 8
           A NVLLAQ
Sbjct: 277 AINVLLAQ 284
>NP_001230242
          Length = 1294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           N+LLA+G
Sbjct: 130 NILLAKG 136
>NP_055670
          Length = 807

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           +VLLAQG
Sbjct: 117 SVLLAQG 123
>NP_005711
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 153 NNVLLAAG 160
>XP_006715889
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 153 NNVLLAAG 160
>XP_006715888
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   HNVLLAQG 9
           +NVLLA G
Sbjct: 153 NNVLLAAG 160
>XP_006712484
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           N+LLA+G
Sbjct: 130 NILLAKG 136
>XP_006712483
          Length = 1306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           N+LLA+G
Sbjct: 130 NILLAKG 136
>XP_005246521
          Length = 1315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   NVLLAQG 9
           N+LLA+G
Sbjct: 130 NILLAKG 136
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.132    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 444,993
Number of extensions: 686
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package