Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_067018                                                              18    1135
NP_008915                                                              18    1135
NP_001153572                                                           18    1135
NP_955360                                                              18    1135
NP_878268                                                              18    1135
NP_001155973                                                           18    1482
NP_055903                                                              18    1482
NP_004432                                                              18    1482
NP_001092007                                                           17    2528
NP_689499                                                              17    2528
NP_001298                                                              17    2528
NP_001171952                                                           17    2528
NP_001171951                                                           17    2528
XP_005266139                                                           17    2528
XP_005266136                                                           17    2528
XP_006717167                                                           17    2528
XP_006717166                                                           17    2528
XP_006717165                                                           17    2528
NP_064517                                                              17    3301
NP_055220                                                              17    3301
XP_006724095                                                           17    3301
XP_006724093                                                           17    3301
XP_006724092                                                           17    3301
XP_005261217                                                           17    3301
XP_005261216                                                           17    3301
NP_114101                                                              17    3301
NP_001032642                                                           17    3301
NP_001191676                                                           17    4312
NP_002904                                                              17    4312
NP_001012780                                                           17    4312
NP_001012777                                                           17    4312
NP_612567                                                              16    5631
NP_003257                                                              16    5631
NP_612564                                                              16    5631
NP_059115                                                              16    5631
NP_036263                                                              16    5631
XP_005260503                                                           16    5631
XP_005260502                                                           16    5631
NP_003042                                                              16    7355
NP_001159968                                                           16    7355
NP_004434                                                              16    7355
NP_001161743                                                           15    9605
NP_694547                                                              15    9605
NP_115627                                                              15    9605
NP_001167621                                                           15    9605
NP_878899                                                              15    9605
NP_001106873                                                           15    9605
NP_001265341                                                           15    9605
NP_001265340                                                           15    9605
NP_085144                                                              15    9605
NP_071896                                                              15    9605
NP_060688                                                              15    9605
NP_060829                                                              15    9605
XP_006723678                                                           15    9605
XP_006719118                                                           15    9605
XP_006719117                                                           15    9605
XP_006718583                                                           15    9605
XP_006718582                                                           15    9605
XP_005270105                                                           15    9605
XP_006713597                                                           15    9605
XP_006713596                                                           15    9605
XP_006713595                                                           15    9605
XP_006713594                                                           15    9605
XP_005247222                                                           15    9605
XP_005246148                                                           15    9605
XP_005246145                                                           15    9605
XP_006712675                                                           15    9605
NP_653233                                                              15    9605
NP_003236                                                              15    9605
>NP_067018
          Length = 220

 Score = 18.5 bits (36), Expect =  1135
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           +G++FV+SG
Sbjct: 121 SGIVFVISG 129
>NP_008915
          Length = 228

 Score = 18.5 bits (36), Expect =  1135
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           AG++F++SG
Sbjct: 120 AGIVFILSG 128
>NP_001153572
          Length = 207

 Score = 18.5 bits (36), Expect =  1135
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           AG++F++SG
Sbjct: 99  AGIVFILSG 107
>NP_955360
          Length = 225

 Score = 18.5 bits (36), Expect =  1135
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           AG+IF+++G
Sbjct: 122 AGIIFIITG 130
>NP_878268
          Length = 226

 Score = 18.5 bits (36), Expect =  1135
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           AG++F++SG
Sbjct: 118 AGIVFILSG 126
>NP_001155973
          Length = 1833

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           AGV FVVSG
Sbjct: 353 AGVNFVVSG 361
>NP_055903
          Length = 1723

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           AGV FVVSG
Sbjct: 353 AGVNFVVSG 361
>NP_004432
          Length = 984

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AGVIFVVS 8
           AGV+FVVS
Sbjct: 548 AGVVFVVS 555
>NP_001092007
          Length = 1342

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 519 ASILFVVSG 527
>NP_689499
          Length = 1317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 494 ASILFVVSG 502
>NP_001298
          Length = 211

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVIFVVSG 9
           G+IF+V+G
Sbjct: 123 GIIFIVAG 130
>NP_001171952
          Length = 145

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVIFVVSG 9
           G+IF+V+G
Sbjct: 123 GIIFIVAG 130
>NP_001171951
          Length = 211

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVIFVVSG 9
           G+IF+V+G
Sbjct: 123 GIIFIVAG 130
>XP_005266139
          Length = 741

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 520 ASILFVVSG 528
>XP_005266136
          Length = 953

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 520 ASILFVVSG 528
>XP_006717167
          Length = 1309

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 486 ASILFVVSG 494
>XP_006717166
          Length = 1316

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 493 ASILFVVSG 501
>XP_006717165
          Length = 1343

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           A ++FVVSG
Sbjct: 520 ASILFVVSG 528
>NP_064517
          Length = 376

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>NP_055220
          Length = 327

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           AG++FV +G
Sbjct: 141 AGILFVAAG 149
>XP_006724095
          Length = 265

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>XP_006724093
          Length = 376

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>XP_006724092
          Length = 376

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>XP_005261217
          Length = 376

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>XP_005261216
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           G +FVVSG
Sbjct: 105 GFVFVVSG 112
>NP_114101
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           AG++FV +G
Sbjct: 162 AGILFVAAG 170
>NP_001032642
          Length = 376

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G +FVVSG
Sbjct: 18 GFVFVVSG 25
>NP_001191676
          Length = 1148

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVIFVVSG 9
           G+IFV++G
Sbjct: 409 GLIFVITG 416
>NP_002904
          Length = 1147

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   GVIFVVSG 9
           G+IFV++G
Sbjct: 409 GLIFVITG 416
>NP_001012780
          Length = 485

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGVIFV  G
Sbjct: 108 AGVIFVDEG 116
>NP_001012777
          Length = 515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGVIFV  G
Sbjct: 108 AGVIFVDEG 116
>NP_612567
          Length = 639

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AGVIFVV 7
           AG+IF+V
Sbjct: 564 AGIIFIV 570
>NP_003257
          Length = 799

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AGVIFVV 7
           AG+IF+V
Sbjct: 724 AGIIFIV 730
>NP_612564
          Length = 839

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AGVIFVV 7
           AG+IF+V
Sbjct: 764 AGIIFIV 770
>NP_059115
          Length = 505

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AGVIFVV 7
           AG+IFV+
Sbjct: 251 AGIIFVI 257
>NP_036263
          Length = 224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AGVIFVVSG 9
           +GV+F+++G
Sbjct: 122 SGVLFILTG 130
>XP_005260503
          Length = 153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G+IFV+ G
Sbjct: 80 GIIFVLEG 87
>XP_005260502
          Length = 271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GVIFVVSG 9
          G+IFV+ G
Sbjct: 80 GIIFVLEG 87
>NP_003042
          Length = 500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           GV+ ++SG
Sbjct: 427 GVVLIISG 434
>NP_001159968
          Length = 500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           GV+ ++SG
Sbjct: 427 GVVLIISG 434
>NP_004434
          Length = 998

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AGVIFVVS 8
           AG++FVV+
Sbjct: 566 AGLVFVVA 573
>NP_001161743
          Length = 810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AGVIFVVS 8
           AG++FVV+
Sbjct: 267 AGLLFVVT 274
>NP_694547
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AGVIFVVS 8
           AG++FVV+
Sbjct: 271 AGLLFVVT 278
>NP_115627
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGV+  +SG
Sbjct: 183 AGVVLALSG 191
>NP_001167621
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 91 GVIFVV 96
>NP_878899
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 91 GVIFVV 96
>NP_001106873
          Length = 258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           +GVI +VSG
Sbjct: 182 SGVIALVSG 190
>NP_001265341
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           +GVI +VSG
Sbjct: 164 SGVIALVSG 172
>NP_001265340
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           +GVI +VSG
Sbjct: 164 SGVIALVSG 172
>NP_085144
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGV  +VSG
Sbjct: 120 AGVTSIVSG 128
>NP_071896
          Length = 800

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           GVI V+SG
Sbjct: 400 GVIKVISG 407
>NP_060688
          Length = 1247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AGVIF+ S
Sbjct: 696 AGVIFINS 703
>NP_060829
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           G+I+VV G
Sbjct: 276 GMIYVVQG 283
>XP_006723678
          Length = 718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AG+IFV S
Sbjct: 185 AGIIFVGS 192
>XP_006719118
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           +GVI +VSG
Sbjct: 164 SGVIALVSG 172
>XP_006719117
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           +GVI +VSG
Sbjct: 133 SGVIALVSG 141
>XP_006718583
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGV+  +SG
Sbjct: 105 AGVVLALSG 113
>XP_006718582
          Length = 1560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGVIFVVSG 9
           AGV+  +SG
Sbjct: 183 AGVVLALSG 191
>XP_005270105
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVIFVVSG 9
           GVI V+SG
Sbjct: 400 GVIKVISG 407
>XP_006713597
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 66 GVIFVV 71
>XP_006713596
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 66 GVIFVV 71
>XP_006713595
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 76 GVIFVV 81
>XP_006713594
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  GVIFVV 7
          GVIFVV
Sbjct: 76 GVIFVV 81
>XP_005247222
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AGVIFVVS 8
           AG++FVV+
Sbjct: 271 AGLLFVVT 278
>XP_005246148
          Length = 1108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AGVIF+ S
Sbjct: 557 AGVIFINS 564
>XP_005246145
          Length = 1236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AGVIF+ S
Sbjct: 685 AGVIFINS 692
>XP_006712675
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AGVIF+ S
Sbjct: 697 AGVIFINS 704
>NP_653233
          Length = 229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGVIFVVSG 9
           AG++F+V G
Sbjct: 214 AGLLFLVVG 222
>NP_003236
          Length = 693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVIFVVS 8
           AG+IFV S
Sbjct: 160 AGIIFVGS 167
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.150    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 397,395
Number of extensions: 972
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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