Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     665
XP_006715292                                                           19     665
NP_055616                                                              17    3301
XP_006711879                                                           17    3301
XP_005273329                                                           17    3301
NP_110415                                                              17    4312
NP_001244246                                                           17    4312
XP_005259159                                                           17    4312
XP_006717495                                                           17    4312
XP_006717494                                                           17    4312
XP_006717493                                                           17    4312
XP_006717492                                                           17    4312
XP_006717490                                                           17    4312
XP_006717489                                                           17    4312
XP_006717488                                                           17    4312
XP_006717487                                                           17    4312
XP_006717486                                                           17    4312
XP_005251132                                                           17    4312
NP_065913                                                              17    4312
NP_055558                                                              16    5631
NP_001094060                                                           16    5631
NP_001275743                                                           16    5631
NP_115826                                                              16    5631
NP_001136018                                                           16    5631
NP_004045                                                              16    5631
NP_361013                                                              16    5631
XP_006722966                                                           16    5631
XP_006722965                                                           16    5631
XP_006722964                                                           16    5631
XP_006716699                                                           16    5631
XP_006716698                                                           16    5631
XP_006716697                                                           16    5631
XP_006716696                                                           16    5631
XP_006716695                                                           16    5631
XP_006716694                                                           16    5631
XP_006716693                                                           16    5631
XP_006716692                                                           16    5631
XP_006716691                                                           16    5631
XP_006716690                                                           16    5631
XP_006716689                                                           16    5631
XP_005248098                                                           16    5631
XP_006713998                                                           16    5631
XP_006713997                                                           16    5631
NP_001129074                                                           16    7355
NP_001073279                                                           16    7355
NP_000395                                                              16    7355
NP_001185739                                                           16    7355
NP_003618                                                              16    7355
NP_001230708                                                           16    7355
NP_006558                                                              16    7355
NP_001230707                                                           16    7355
NP_001230711                                                           16    7355
NP_001230710                                                           16    7355
XP_005274415                                                           16    7355
XP_005274414                                                           16    7355
XP_005270278                                                           16    7355
XP_005248871                                                           16    7355
XP_006715029                                                           16    7355
XP_005248870                                                           16    7355
XP_005248868                                                           16    7355
XP_005248869                                                           16    7355
NP_001230709                                                           16    7355
NP_115709                                                              16    7355
NP_001136272                                                           15    9605
NP_001244963                                                           15    9605
NP_001244965                                                           15    9605
NP_060589                                                              15    9605
NP_001244964                                                           15    9605
NP_001244962                                                           15    9605
XP_006726676                                                           15    9605
XP_005276555                                                           15    9605
XP_006721126                                                           15    9605
>NP_115927
          Length = 1321

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGTDAFLST 9
           AGTDA LST
Sbjct: 313 AGTDALLST 321
>XP_006715292
          Length = 759

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGTDAFLST 9
           AGTDA LST
Sbjct: 300 AGTDALLST 308
>NP_055616
          Length = 2137

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           +GTD FLS
Sbjct: 535 SGTDVFLS 542
>XP_006711879
          Length = 1364

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           +GTD FLS
Sbjct: 535 SGTDVFLS 542
>XP_005273329
          Length = 1934

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           +GTD FLS
Sbjct: 332 SGTDVFLS 339
>NP_110415
          Length = 470

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AGTDAFLS 8
          +GTD FLS
Sbjct: 6  SGTDIFLS 13
>NP_001244246
          Length = 283

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AGTDAFLS 8
          +GTD FLS
Sbjct: 6  SGTDIFLS 13
>XP_005259159
          Length = 771

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           A  DAFLST
Sbjct: 155 AAFDAFLST 163
>XP_006717495
          Length = 1037

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_006717494
          Length = 1571

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 318 AGTDAYKKT 326
>XP_006717493
          Length = 1610

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 357 AGTDAYKKT 365
>XP_006717492
          Length = 1635

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_006717490
          Length = 1791

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 538 AGTDAYKKT 546
>XP_006717489
          Length = 1945

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_006717488
          Length = 2031

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_006717487
          Length = 2071

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_006717486
          Length = 2072

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           AGTDA+  T
Sbjct: 819 AGTDAYKKT 827
>XP_005251132
          Length = 470

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AGTDAFLS 8
          +GTD FLS
Sbjct: 6  SGTDIFLS 13
>NP_065913
          Length = 771

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGTDAFLST 9
           A  DAFLST
Sbjct: 155 AAFDAFLST 163
>NP_055558
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           AGTD F++
Sbjct: 970 AGTDVFMT 977
>NP_001094060
          Length = 1395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           AGTD F++
Sbjct: 970 AGTDVFMT 977
>NP_001275743
          Length = 1632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>NP_115826
          Length = 1641

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>NP_001136018
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTDAFLST 9
           G DAFLS+
Sbjct: 360 GEDAFLSS 367
>NP_004045
          Length = 482

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TDAFLST 9
           +DAFLST
Sbjct: 286 SDAFLST 292
>NP_361013
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTDAFLST 9
           G DAFLS+
Sbjct: 360 GEDAFLSS 367
>XP_006722966
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTDAFLST 9
           G +AFLST
Sbjct: 427 GPEAFLST 434
>XP_006722965
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTDAFLST 9
           G +AFLST
Sbjct: 471 GPEAFLST 478
>XP_006722964
          Length = 581

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTDAFLST 9
           G +AFLST
Sbjct: 516 GPEAFLST 523
>XP_006716699
          Length = 1147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716698
          Length = 1481

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716697
          Length = 1578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716696
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 450 AGADAFL 456
>XP_006716695
          Length = 1585

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 450 AGADAFL 456
>XP_006716694
          Length = 1632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716693
          Length = 1644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716692
          Length = 1644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716691
          Length = 1653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716690
          Length = 1653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_006716689
          Length = 1653

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 518 AGADAFL 524
>XP_005248098
          Length = 1310

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           AGTD F++
Sbjct: 861 AGTDVFMT 868
>XP_006713998
          Length = 1332

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           AGTD F++
Sbjct: 970 AGTDVFMT 977
>XP_006713997
          Length = 1419

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGTDAFLS 8
           AGTD F++
Sbjct: 970 AGTDVFMT 977
>NP_001129074
          Length = 546

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TDAFLS 8
           TDAFLS
Sbjct: 118 TDAFLS 123
>NP_001073279
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TDAFLS 8
           TDAFLS
Sbjct: 219 TDAFLS 224
>NP_000395
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TDAFLS 8
           TDAFLS
Sbjct: 249 TDAFLS 254
>NP_001185739
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GTDAFLS 8
           G+DAF+S
Sbjct: 271 GSDAFMS 277
>NP_003618
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GTDAFLS 8
           G+DAF+S
Sbjct: 271 GSDAFMS 277
>NP_001230708
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 32 ANTDVFLS 39
>NP_006558
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>NP_001230707
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 32 ANTDVFLS 39
>NP_001230711
          Length = 225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 28 ANTDVFLS 35
>NP_001230710
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 21 ANTDVFLS 28
>XP_005274415
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GTDAFLS 8
           G+DAF+S
Sbjct: 287 GSDAFMS 293
>XP_005274414
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GTDAFLS 8
           G+DAF+S
Sbjct: 297 GSDAFMS 303
>XP_005270278
          Length = 236

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 39 ANTDVFLS 46
>XP_005248871
          Length = 226

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>XP_006715029
          Length = 305

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>XP_005248870
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>XP_005248868
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>XP_005248869
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGTDAFL 7
           AG DAFL
Sbjct: 166 AGLDAFL 172
>NP_001230709
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 32 ANTDVFLS 39
>NP_115709
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AGTDAFLS 8
          A TD FLS
Sbjct: 32 ANTDVFLS 39
>NP_001136272
          Length = 3144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    AGTDAF 6
            +GTDAF
Sbjct: 2419 SGTDAF 2424
>NP_001244963
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 504 AGTDSF 509
>NP_001244965
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
>NP_060589
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
>NP_001244964
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 504 AGTDSF 509
>NP_001244962
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
>XP_006726676
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
>XP_005276555
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
>XP_006721126
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGTDAF 6
           AGTD+F
Sbjct: 540 AGTDSF 545
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.124    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 541,637
Number of extensions: 1155
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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