Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              19     869
NP_001035957                                                           19     869
XP_006721990                                                           19     869
XP_006721989                                                           19     869
XP_005258041                                                           19     869
XP_006721988                                                           19     869
XP_006721987                                                           19     869
XP_006721986                                                           19     869
XP_005258040                                                           19     869
XP_006721985                                                           19     869
NP_005793                                                              16    5631
NP_001182551                                                           16    5631
NP_004739                                                              16    7355
NP_001191379                                                           16    7355
NP_056053                                                              16    7355
NP_001191380                                                           16    7355
NP_065790                                                              16    7355
NP_001155134                                                           16    7355
NP_001155133                                                           16    7355
XP_006714899                                                           16    7355
XP_005265910                                                           16    7355
XP_006714898                                                           16    7355
XP_005265909                                                           16    7355
XP_005265908                                                           16    7355
XP_005265907                                                           16    7355
NP_057726                                                              15    9605
NP_056305                                                              15    9605
NP_036222                                                              15    9605
NP_149038                                                              15    9605
NP_078993                                                              15    9605
NP_079123                                                              15    9605
NP_001153836                                                           15    9605
XP_006721157                                                           15    9605
XP_005255654                                                           15    9605
XP_005254495                                                           15    9605
XP_006710603                                                           15    9605
XP_006710602                                                           15    9605
XP_006710600                                                           15    9605
XP_005270757                                                           15    9605
XP_006710599                                                           15    9605
XP_006710598                                                           15    9605
XP_006710597                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710588                                                           15    9605
XP_006710587                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
NP_005530                                                              15    9605
>NP_000258
          Length = 2818

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2312 AGTALLEQ 2319
>NP_001035957
          Length = 2839

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2333 AGTALLEQ 2340
>XP_006721990
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2343 AGTALLEQ 2350
>XP_006721989
          Length = 2823

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2343 AGTALLEQ 2350
>XP_005258041
          Length = 2836

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2312 AGTALLEQ 2319
>XP_006721988
          Length = 2846

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2322 AGTALLEQ 2329
>XP_006721987
          Length = 2849

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2343 AGTALLEQ 2350
>XP_006721986
          Length = 2854

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2330 AGTALLEQ 2337
>XP_005258040
          Length = 2857

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2333 AGTALLEQ 2340
>XP_006721985
          Length = 2867

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AGTALLEQ 8
            AGTALLEQ
Sbjct: 2343 AGTALLEQ 2350
>NP_005793
          Length = 1045

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AGTALLEQT 9
          AGT+ L+QT
Sbjct: 84 AGTSKLQQT 92
>NP_001182551
          Length = 980

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AGTALLEQT 9
          AGT+ L+QT
Sbjct: 19 AGTSKLQQT 27
>NP_004739
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GTALLEQT 9
          GT L+E+T
Sbjct: 64 GTVLMEET 71
>NP_001191379
          Length = 807

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GTALLEQT 9
          GT L+E+T
Sbjct: 64 GTVLMEET 71
>NP_056053
          Length = 1113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 813 AVSALLEQT 821
>NP_001191380
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GTALLEQT 9
          GT L+E+T
Sbjct: 64 GTVLMEET 71
>NP_065790
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GTALLEQT 9
          GT L+E+T
Sbjct: 64 GTVLMEET 71
>NP_001155134
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 813 AVSALLEQT 821
>NP_001155133
          Length = 1119

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 813 AVSALLEQT 821
>XP_006714899
          Length = 881

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 575 AVSALLEQT 583
>XP_005265910
          Length = 1112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 813 AVSALLEQT 821
>XP_006714898
          Length = 1117

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 818 AVSALLEQT 826
>XP_005265909
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 818 AVSALLEQT 826
>XP_005265908
          Length = 1123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 818 AVSALLEQT 826
>XP_005265907
          Length = 1124

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AGTALLEQT 9
           A +ALLEQT
Sbjct: 818 AVSALLEQT 826
>NP_057726
          Length = 3674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           A  ALLEQT
Sbjct: 630 ARRALLEQT 638
>NP_056305
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GTALLEQT 9
           GT LL+QT
Sbjct: 600 GTDLLKQT 607
>NP_036222
          Length = 5430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 3559 GQALLKQT 3566
>NP_149038
          Length = 512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GTALLE 7
           GTALLE
Sbjct: 159 GTALLE 164
>NP_078993
          Length = 999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GTALLEQ 8
           GTA LEQ
Sbjct: 203 GTACLEQ 209
>NP_079123
          Length = 723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           +GT  LE+T
Sbjct: 235 SGTGFLEET 243
>NP_001153836
          Length = 613

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           +GT  LE+T
Sbjct: 125 SGTGFLEET 133
>XP_006721157
          Length = 671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           +GT  LE+T
Sbjct: 235 SGTGFLEET 243
>XP_005255654
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           +GT  LE+T
Sbjct: 235 SGTGFLEET 243
>XP_005254495
          Length = 3694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AGTALLEQT 9
           A  ALLEQT
Sbjct: 650 ARRALLEQT 658
>XP_006710603
          Length = 5324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 3450 GQALLKQT 3457
>XP_006710602
          Length = 7391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5517 GQALLKQT 5524
>XP_006710600
          Length = 5384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 3450 GQALLKQT 3457
>XP_005270757
          Length = 5460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 3589 GQALLKQT 3596
>XP_006710599
          Length = 5656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 3719 GQALLKQT 3726
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5616 GQALLKQT 5623
>XP_006710597
          Length = 7451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5517 GQALLKQT 5524
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5575 GQALLKQT 5582
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5589 GQALLKQT 5596
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5591 GQALLKQT 5598
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5602 GQALLKQT 5609
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5607 GQALLKQT 5614
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5621 GQALLKQT 5628
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5626 GQALLKQT 5633
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5658 GQALLKQT 5665
>XP_006710588
          Length = 7614

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5677 GQALLKQT 5684
>XP_006710587
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5708 GQALLKQT 5715
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5765 GQALLKQT 5772
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GTALLEQT 9
            G ALL+QT
Sbjct: 5786 GQALLKQT 5793
>NP_005530
          Length = 412

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GTALLE 7
           GTALLE
Sbjct: 299 GTALLE 304
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.304    0.118    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 483,281
Number of extensions: 692
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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