Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_996563                                                              20     390
NP_789765                                                              18    1482
NP_001123914                                                           18    1482
NP_005334                                                              18    1482
NP_004976                                                              18    1482
NP_203524                                                              18    1482
NP_002515                                                              18    1482
XP_006725199                                                           18    1482
XP_006719132                                                           18    1482
XP_006718280                                                           18    1482
NP_005393                                                              17    3301
NP_689935                                                              17    3301
NP_002872                                                              17    3301
NP_002877                                                              17    3301
NP_001238851                                                           17    3301
NP_001238847                                                           17    3301
NP_001238846                                                           17    3301
NP_056461                                                              17    3301
NP_001238850                                                           17    3301
NP_001010942                                                           17    3301
NP_067006                                                              17    3301
NP_001258115                                                           17    3301
XP_005271506                                                           17    3301
XP_006718849                                                           17    3301
XP_006715826                                                           17    3301
XP_006715825                                                           17    3301
XP_005263786                                                           17    3301
XP_005263785                                                           17    3301
XP_005263784                                                           17    3301
XP_005263781                                                           17    3301
XP_006710866                                                           17    3301
NP_066361                                                              17    3301
NP_001010935                                                           17    3301
NP_002875                                                              17    3301
NP_001078518                                                           17    4312
NP_036351                                                              17    4312
NP_001239019                                                           17    4312
NP_036382                                                              17    4312
NP_006261                                                              17    4312
XP_005247286                                                           17    4312
XP_005247285                                                           17    4312
NP_001449                                                              16    5631
NP_001120959                                                           16    5631
NP_001159506                                                           16    5631
XP_006715973                                                           16    5631
NP_853510                                                              16    7355
NP_001244067                                                           15    9605
NP_001274420                                                           15    9605
NP_113671                                                              15    9605
NP_001244066                                                           15    9605
NP_001157935                                                           15    9605
NP_001116835                                                           15    9605
NP_036526                                                              15    9605
NP_005045                                                              15    9605
NP_001032955                                                           15    9605
XP_005260627                                                           15    9605
XP_006723945                                                           15    9605
XP_006723944                                                           15    9605
XP_005263879                                                           15    9605
XP_005263878                                                           15    9605
XP_005263877                                                           15    9605
XP_005263876                                                           15    9605
XP_006712857                                                           15    9605
XP_005263813                                                           15    9605
XP_005263812                                                           15    9605
XP_005263810                                                           15    9605
XP_005263805                                                           15    9605
XP_005263804                                                           15    9605
XP_006712026                                                           15    9605
XP_005264244                                                           15    9605
NP_115636                                                              15    9605
>NP_996563
          Length = 242

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1  AGRVGKSAL 9
          AGRVGKSA+
Sbjct: 35 AGRVGKSAM 43
>NP_789765
          Length = 170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_001123914
          Length = 189

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_005334
          Length = 189

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_004976
          Length = 188

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_203524
          Length = 189

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_002515
          Length = 189

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>XP_006725199
          Length = 170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>XP_006719132
          Length = 189

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>XP_006718280
          Length = 170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          AG VGKSAL
Sbjct: 11 AGGVGKSAL 19
>NP_005393
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>NP_689935
          Length = 416

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 45 GTVGKSAL 52
>NP_002872
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>NP_002877
          Length = 183

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001238851
          Length = 137

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001238847
          Length = 142

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001238846
          Length = 142

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_056461
          Length = 184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001238850
          Length = 165

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001010942
          Length = 184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_067006
          Length = 183

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001258115
          Length = 183

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>XP_005271506
          Length = 415

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 45 GTVGKSAL 52
>XP_006718849
          Length = 423

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 45 GTVGKSAL 52
>XP_006715826
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>XP_006715825
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>XP_005263786
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>XP_005263785
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>XP_005263784
          Length = 206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 22 SGGVGKSAL 30
>XP_005263781
          Length = 228

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 44 SGGVGKSAL 52
>XP_006710866
          Length = 184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_066361
          Length = 183

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001010935
          Length = 184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_002875
          Length = 184

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGRVGKSAL 9
          +G VGKSAL
Sbjct: 11 SGGVGKSAL 19
>NP_001078518
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 22 GGVGKSAL 29
>NP_036351
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 22 GGVGKSAL 29
>NP_001239019
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 22 GGVGKSAL 29
>NP_036382
          Length = 204

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 23 GGVGKSAL 30
>NP_006261
          Length = 218

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 38 GGVGKSAL 45
>XP_005247286
          Length = 170

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 22 GGVGKSAL 29
>XP_005247285
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  GRVGKSAL 9
          G VGKSAL
Sbjct: 22 GGVGKSAL 29
>NP_001449
          Length = 2725

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GRVGKSA 8
           G+VGKSA
Sbjct: 584 GQVGKSA 590
>NP_001120959
          Length = 2692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GRVGKSA 8
           G+VGKSA
Sbjct: 584 GQVGKSA 590
>NP_001159506
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGRVGKSA 8
           AG+VGK A
Sbjct: 123 AGQVGKEA 130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGRVGKSA 8
           AG+VGK A
Sbjct: 232 AGQVGKEA 239

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGRVGKSA 8
           AG+VGK A
Sbjct: 286 AGQVGKEA 293
>XP_006715973
          Length = 2632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GRVGKSA 8
           G+VGKSA
Sbjct: 584 GQVGKSA 590
>NP_853510
          Length = 233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  AGRVGKSAL 9
          A  VGKSAL
Sbjct: 49 ASGVGKSAL 57
>NP_001244067
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 359 RTGKSAL 365
>NP_001274420
          Length = 1795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AGRVGKSAL 9
            AG++GK+ L
Sbjct: 1414 AGKMGKTPL 1422
>NP_113671
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 469 RTGKSAL 475
>NP_001244066
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 510 RTGKSAL 516
>NP_001157935
          Length = 1765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>NP_001116835
          Length = 1765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>NP_036526
          Length = 154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AGRVGKSA 8
          +GR GKS+
Sbjct: 5  SGRAGKSS 12
>NP_005045
          Length = 1765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>NP_001032955
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>XP_005260627
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 299 RTGKSAL 305
>XP_006723945
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 359 RTGKSAL 365
>XP_006723944
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   RVGKSAL 9
           R GKSAL
Sbjct: 469 RTGKSAL 475
>XP_005263879
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 93  ANKIGQSAL 101
>XP_005263878
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>XP_005263877
          Length = 1686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>XP_005263876
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 352 ANKIGQSAL 360
>XP_006712857
          Length = 1748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 361 ANKIGQSAL 369
>XP_005263813
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 93  ANKIGQSAL 101
>XP_005263812
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>XP_005263810
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 352 ANKIGQSAL 360
>XP_005263805
          Length = 1480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 93  ANKIGQSAL 101
>XP_005263804
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
>XP_006712026
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           AG++GK+ L
Sbjct: 556 AGKMGKTPL 564
>XP_005264244
          Length = 1795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AGRVGKSAL 9
            AG++GK+ L
Sbjct: 1414 AGKMGKTPL 1422
>NP_115636
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGRVGKSAL 9
           A ++G+SAL
Sbjct: 378 ANKIGQSAL 386
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.130    0.340 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 486,624
Number of extensions: 651
Number of successful extensions: 73
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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