Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_789765                                                              19     665
NP_001123914                                                           19     665
NP_005334                                                              19     665
NP_004976                                                              19     665
NP_203524                                                              19     665
NP_002515                                                              19     665
XP_006725199                                                           19     665
XP_006719132                                                           19     665
XP_006718280                                                           19     665
NP_001078518                                                           18    1935
NP_036351                                                              18    1935
NP_001239019                                                           18    1935
XP_005247286                                                           18    1935
XP_005247285                                                           18    1935
NP_060907                                                              17    4312
NP_940863                                                              17    4312
NP_932095                                                              17    4312
XP_005252145                                                           17    4312
XP_006717237                                                           17    4312
XP_005252143                                                           17    4312
NP_002197                                                              16    5631
NP_001138468                                                           16    5631
NP_001138469                                                           16    5631
NP_065120                                                              16    5631
NP_003794                                                              16    5631
NP_062830                                                              16    5631
XP_006721915                                                           16    5631
XP_005268907                                                           16    5631
XP_005268906                                                           16    5631
XP_005268905                                                           16    5631
XP_005268904                                                           16    5631
XP_005268903                                                           16    5631
XP_005268902                                                           16    5631
XP_005268901                                                           16    5631
XP_005268899                                                           16    5631
XP_005268898                                                           16    5631
XP_005268897                                                           16    5631
XP_005268896                                                           16    5631
NP_055418                                                              16    5631
NP_057717                                                              16    7355
XP_005255408                                                           16    7355
XP_005255409                                                           16    7355
XP_005265403                                                           16    7355
NP_000542                                                              15    9605
NP_937799                                                              15    9605
NP_055558                                                              15    9605
NP_001094060                                                           15    9605
NP_742034                                                              15    9605
NP_001229527                                                           15    9605
NP_055514                                                              15    9605
NP_115597                                                              15    9605
NP_060787                                                              15    9605
NP_689739                                                              15    9605
NP_476518                                                              15    9605
NP_995585                                                              15    9605
NP_116024                                                              15    9605
XP_005260633                                                           15    9605
XP_005260632                                                           15    9605
XP_005260631                                                           15    9605
XP_005260630                                                           15    9605
XP_005255769                                                           15    9605
XP_005255768                                                           15    9605
XP_005255767                                                           15    9605
XP_005249698                                                           15    9605
XP_005248229                                                           15    9605
XP_006714030                                                           15    9605
XP_005248098                                                           15    9605
XP_006713997                                                           15    9605
XP_005246331                                                           15    9605
XP_005246330                                                           15    9605
NP_001129396                                                           15    9605
>NP_789765
          Length = 170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_001123914
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_005334
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_004976
          Length = 188

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_203524
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_002515
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>XP_006725199
          Length = 170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>XP_006719132
          Length = 189

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>XP_006718280
          Length = 170

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EEYSAM
Sbjct: 59 AGQEEYSAM 67
>NP_001078518
          Length = 208

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EE+SAM
Sbjct: 69 AGQEEFSAM 77
>NP_036351
          Length = 208

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EE+SAM
Sbjct: 69 AGQEEFSAM 77
>NP_001239019
          Length = 208

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EE+SAM
Sbjct: 69 AGQEEFSAM 77
>XP_005247286
          Length = 170

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EE+SAM
Sbjct: 69 AGQEEFSAM 77
>XP_005247285
          Length = 208

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AG EE+SAM
Sbjct: 69 AGQEEFSAM 77
>NP_060907
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEYS
Sbjct: 376 GLEEYS 381
>NP_940863
          Length = 754

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   AGLEEYSAM 9
           AGL EY  M
Sbjct: 585 AGLSEYGCM 593
>NP_932095
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEYS
Sbjct: 376 GLEEYS 381
>XP_005252145
          Length = 309

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEYS
Sbjct: 201 GLEEYS 206
>XP_006717237
          Length = 470

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEYS
Sbjct: 376 GLEEYS 381
>XP_005252143
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEYS
Sbjct: 376 GLEEYS 381
>NP_002197
          Length = 1137

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 985 LEEYSAV 991
>NP_001138468
          Length = 1141

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 989 LEEYSAV 995
>NP_001138469
          Length = 1044

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 892 LEEYSAV 898
>NP_065120
          Length = 213

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGLEEYSAM 9
          AGLE Y A+
Sbjct: 69 AGLERYRAI 77
>NP_003794
          Length = 1685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGLEEYS 7
           AGL EYS
Sbjct: 817 AGLSEYS 823
>NP_062830
          Length = 1589

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGLEEYS 7
           AGL EYS
Sbjct: 817 AGLSEYS 823
>XP_006721915
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AGLEEYSA 8
          AG+E++SA
Sbjct: 5  AGMEDFSA 12
>XP_005268907
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 827 LEEYSAV 833
>XP_005268906
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 871 LEEYSAV 877
>XP_005268905
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 871 LEEYSAV 877
>XP_005268904
          Length = 1023

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 871 LEEYSAV 877
>XP_005268903
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 872 LEEYSAV 878
>XP_005268902
          Length = 1024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 872 LEEYSAV 878
>XP_005268901
          Length = 1068

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 916 LEEYSAV 922
>XP_005268899
          Length = 1131

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LEEYSAM 9
           LEEYSA+
Sbjct: 979 LEEYSAV 985
>XP_005268898
          Length = 1162

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LEEYSAM 9
            LEEYSA+
Sbjct: 1029 LEEYSAV 1035
>XP_005268897
          Length = 1175

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LEEYSAM 9
            LEEYSA+
Sbjct: 1023 LEEYSAV 1029
>XP_005268896
          Length = 1181

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LEEYSAM 9
            LEEYSA+
Sbjct: 1029 LEEYSAV 1035
>NP_055418
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AGLEEYSA 8
          AG+E++SA
Sbjct: 5  AGMEDFSA 12
>NP_057717
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AGL+E+S +
Sbjct: 13 AGLKEFSVL 21
>XP_005255408
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AGL+E+S +
Sbjct: 13 AGLKEFSVL 21
>XP_005255409
          Length = 102

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AGLEEYSAM 9
          AGL+E+S +
Sbjct: 13 AGLKEFSVL 21
>XP_005265403
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AGLEEYS 7
           +GLE+YS
Sbjct: 648 SGLEDYS 654
>NP_000542
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  AGLEEY 6
          AG+EEY
Sbjct: 18 AGVEEY 23
>NP_937799
          Length = 172

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  AGLEEY 6
          AG+EEY
Sbjct: 18 AGVEEY 23
>NP_055558
          Length = 1395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    AGLEEY 6
            +GLEEY
Sbjct: 1313 SGLEEY 1318
>NP_001094060
          Length = 1395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    AGLEEY 6
            +GLEEY
Sbjct: 1313 SGLEEY 1318
>NP_742034
          Length = 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AGLEEYSA 8
           AG+E+Y A
Sbjct: 205 AGVEDYCA 212
>NP_001229527
          Length = 150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AGLEEYSA 8
          +GL EY+A
Sbjct: 24 SGLSEYNA 31
>NP_055514
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGLEEY 6
           +GLEEY
Sbjct: 366 SGLEEY 371
>NP_115597
          Length = 2715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    GLEEYSA 8
            GLE++SA
Sbjct: 2193 GLEQFSA 2199
>NP_060787
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEY+
Sbjct: 350 GLEEYA 355
>NP_689739
          Length = 1143

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLE+YS
Sbjct: 606 GLEDYS 611
>NP_476518
          Length = 1136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLE+YS
Sbjct: 668 GLEDYS 673
>NP_995585
          Length = 1104

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLE+YS
Sbjct: 668 GLEDYS 673
>NP_116024
          Length = 224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  AGLEEYSA 8
          +GL EY+A
Sbjct: 24 SGLSEYNA 31
>XP_005260633
          Length = 1364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   GLEEYSA 8
           GLE++SA
Sbjct: 842 GLEQFSA 848
>XP_005260632
          Length = 2377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    GLEEYSA 8
            GLE++SA
Sbjct: 2193 GLEQFSA 2199
>XP_005260631
          Length = 2667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    GLEEYSA 8
            GLE++SA
Sbjct: 2145 GLEQFSA 2151
>XP_005260630
          Length = 2693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    GLEEYSA 8
            GLE++SA
Sbjct: 2171 GLEQFSA 2177
>XP_005255769
          Length = 1808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGLEEY 6
           +GLEEY
Sbjct: 366 SGLEEY 371
>XP_005255768
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGLEEY 6
           +GLEEY
Sbjct: 366 SGLEEY 371
>XP_005255767
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AGLEEY 6
           +GLEEY
Sbjct: 366 SGLEEY 371
>XP_005249698
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGLEEYSAM 9
           +GL EYS +
Sbjct: 253 SGLTEYSTL 261
>XP_005248229
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEY+
Sbjct: 285 GLEEYA 290
>XP_006714030
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLEEY+
Sbjct: 319 GLEEYA 324
>XP_005248098
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    AGLEEY 6
            +GLEEY
Sbjct: 1228 SGLEEY 1233
>XP_006713997
          Length = 1419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    AGLEEY 6
            +GLEEY
Sbjct: 1337 SGLEEY 1342
>XP_005246331
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLE+YS
Sbjct: 469 GLEDYS 474
>XP_005246330
          Length = 1205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   GLEEYS 7
           GLE+YS
Sbjct: 668 GLEDYS 673
>NP_001129396
          Length = 1590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AGLEEYSAM 9
           +GL EYS +
Sbjct: 799 SGLTEYSTL 807
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.119    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 622,974
Number of extensions: 874
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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