Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006715                                                              17    3301
NP_005913                                                              17    3301
XP_005267046                                                           17    3301
XP_005267045                                                           17    3301
NP_060549                                                              17    4312
XP_005264455                                                           17    4312
NP_001124468                                                           16    5631
NP_000850                                                              16    5631
NP_003162                                                              16    5631
XP_005270125                                                           16    5631
NP_001288                                                              16    7355
NP_003310                                                              16    7355
NP_001273059                                                           16    7355
NP_597676                                                              16    7355
NP_001243779                                                           16    7355
NP_596869                                                              16    7355
NP_001269462                                                           16    7355
XP_005260950                                                           16    7355
XP_005260949                                                           16    7355
XP_005260948                                                           16    7355
XP_005260947                                                           16    7355
XP_006721197                                                           16    7355
XP_005246888                                                           16    7355
XP_006712788                                                           16    7355
XP_006712787                                                           16    7355
XP_006712786                                                           16    7355
NP_001254479                                                           16    7355
NP_597681                                                              16    7355
NP_001018098                                                           15    9605
NP_005236                                                              15    9605
NP_060154                                                              15    9605
NP_060550                                                              15    9605
NP_065872                                                              15    9605
NP_001240841                                                           15    9605
NP_055988                                                              15    9605
NP_001008781                                                           15    9605
XP_006718827                                                           15    9605
XP_006714202                                                           15    9605
XP_005262892                                                           15    9605
XP_005262891                                                           15    9605
XP_006714064                                                           15    9605
XP_005262708                                                           15    9605
XP_005262706                                                           15    9605
XP_006714063                                                           15    9605
XP_005262705                                                           15    9605
XP_006714062                                                           15    9605
XP_005262704                                                           15    9605
XP_005262703                                                           15    9605
>NP_006715
          Length = 1558

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AGE SLLSI
Sbjct: 640 AGEPSLLSI 648
>NP_005913
          Length = 1608

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AGE SLLSI
Sbjct: 640 AGEPSLLSI 648
>XP_005267046
          Length = 1554

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AGE SLLSI
Sbjct: 640 AGEPSLLSI 648
>XP_005267045
          Length = 1604

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AGE SLLSI
Sbjct: 640 AGEPSLLSI 648
>NP_060549
          Length = 995

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLLS
Sbjct: 344 GELSLLS 350
>XP_005264455
          Length = 671

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLLS
Sbjct: 344 GELSLLS 350
>NP_001124468
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AGELSLLS 8
           AGELSL++
Sbjct: 795 AGELSLMA 802
>NP_000850
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AGELSLLS 8
           AGELSL++
Sbjct: 848 AGELSLMA 855
>NP_003162
          Length = 786

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AGELSLLS 8
           AGELSL S
Sbjct: 728 AGELSLAS 735
>XP_005270125
          Length = 655

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AGELSLLS 8
           AGELSL S
Sbjct: 597 AGELSLAS 604
>NP_001288
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    GELSLLSI 9
            GE+SLL++
Sbjct: 1029 GEISLLAV 1036
>NP_003310
          Length = 26926

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 23938 GELEILSI 23945
>NP_001273059
          Length = 1245

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    GELSLLSI 9
            GE+SLL++
Sbjct: 1023 GEISLLAV 1030
>NP_597676
          Length = 27051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 24063 GELEILSI 24070
>NP_001243779
          Length = 34350

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 31362 GELEILSI 31369
>NP_596869
          Length = 33423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 30435 GELEILSI 30442
>NP_001269462
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGELSLL 7
           AGE+SLL
Sbjct: 400 AGEISLL 406
>XP_005260950
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGELSLL 7
           AGE+SLL
Sbjct: 446 AGEISLL 452
>XP_005260949
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGELSLL 7
           AGE+SLL
Sbjct: 446 AGEISLL 452
>XP_005260948
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGELSLL 7
           AGE+SLL
Sbjct: 455 AGEISLL 461
>XP_005260947
          Length = 703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGELSLL 7
           AGE+SLL
Sbjct: 476 AGEISLL 482
>XP_006721197
          Length = 1251

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    GELSLLSI 9
            GE+SLL++
Sbjct: 1029 GEISLLAV 1036
>XP_005246888
          Length = 22663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 19675 GELEILSI 19682
>XP_006712788
          Length = 24022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 21034 GELEILSI 21041
>XP_006712787
          Length = 33978

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 30990 GELEILSI 30997
>XP_006712786
          Length = 35484

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 32496 GELEILSI 32503
>NP_001254479
          Length = 35991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 33003 GELEILSI 33010
>NP_597681
          Length = 27118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2     GELSLLSI 9
             GEL +LSI
Sbjct: 24130 GELEILSI 24137
>NP_001018098
          Length = 3628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLL+
Sbjct: 223 GELSLLT 229
>NP_005236
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AGELSLLSI 9
            AGE  +LSI
Sbjct: 1317 AGEYDILSI 1325
>NP_060154
          Length = 3710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLL+
Sbjct: 180 GELSLLT 186
>NP_060550
          Length = 3585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLL+
Sbjct: 180 GELSLLT 186
>NP_065872
          Length = 3753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   GELSLLS 8
           GELSLL+
Sbjct: 223 GELSLLT 229
>NP_001240841
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 962 AGQLSLYNI 970
>NP_055988
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 868 AGQLSLYNI 876
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GELSLLSI 9
            GELSL S+
Sbjct: 4537 GELSLASL 4544
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    GELSLLSI 9
            GELSL S+
Sbjct: 3459 GELSLASL 3466
>XP_006714202
          Length = 4588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AGELSLLSI 9
            AGE  +LSI
Sbjct: 1317 AGEYDILSI 1325
>XP_005262892
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AGELSLLSI 9
            AGE  +LSI
Sbjct: 1317 AGEYDILSI 1325
>XP_005262891
          Length = 4600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AGELSLLSI 9
            AGE  +LSI
Sbjct: 1317 AGEYDILSI 1325
>XP_006714064
          Length = 546

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 246 AGQLSLYNI 254
>XP_005262708
          Length = 1039

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 739 AGQLSLYNI 747
>XP_005262706
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 846 AGQLSLYNI 854
>XP_006714063
          Length = 1168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 868 AGQLSLYNI 876
>XP_005262705
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 881 AGQLSLYNI 889
>XP_006714062
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 962 AGQLSLYNI 970
>XP_005262704
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 962 AGQLSLYNI 970
>XP_005262703
          Length = 1275

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AGELSLLSI 9
           AG+LSL +I
Sbjct: 975 AGQLSLYNI 983
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.134    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 376,946
Number of extensions: 475
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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