Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           21     229
NP_001277143                                                           21     229
NP_001319                                                              21     229
NP_001012632                                                           21     229
NP_001077383                                                           21     229
NP_001320                                                              21     229
NP_073713                                                              21     229
XP_005269629                                                           21     229
XP_005269628                                                           21     229
XP_005269627                                                           21     229
XP_005269626                                                           21     229
XP_006717706                                                           21     229
XP_005269625                                                           21     229
XP_005269624                                                           21     229
XP_006717705                                                           21     229
XP_005269622                                                           21     229
XP_005269621                                                           21     229
XP_006717704                                                           21     229
XP_005269619                                                           21     229
XP_005269618                                                           21     229
XP_005272320                                                           21     229
XP_005272319                                                           21     229
XP_005272318                                                           21     229
NP_055570                                                              17    4312
XP_005276368                                                           17    4312
XP_005250138                                                           17    4312
XP_005264726                                                           17    4312
XP_005276070                                                           17    4312
NP_001180473                                                           16    7355
NP_001146                                                              16    7355
XP_005268489                                                           16    7355
NP_003059                                                              15    9605
NP_699193                                                              15    9605
NP_001163894                                                           15    9605
NP_001012977                                                           15    9605
>NP_001277144
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>NP_001277143
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>NP_001319
          Length = 440

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 52 AFCDAQSTQ 60
>NP_001012632
          Length = 429

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 41 AFCDAQSTQ 49
>NP_001077383
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>NP_001320
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>NP_073713
          Length = 985

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AFCDAQSMQ 9
           AFCDAQS Q
Sbjct: 598 AFCDAQSTQ 606
>XP_005269629
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269628
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269627
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269626
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_006717706
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269625
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269624
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_006717705
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269622
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269621
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_006717704
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269619
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005269618
          Length = 445

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 58 AFCDAQSTQ 66
>XP_005272320
          Length = 430

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 41 AFCDAQSTQ 49
>XP_005272319
          Length = 430

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 41 AFCDAQSTQ 49
>XP_005272318
          Length = 441

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          AFCDAQS Q
Sbjct: 52 AFCDAQSTQ 60
>NP_055570
          Length = 314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FCDAQSMQ 9
           FC +Q+MQ
Sbjct: 143 FCTSQAMQ 150
>XP_005276368
          Length = 103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  AFCDAQ 6
          A+CDAQ
Sbjct: 46 AYCDAQ 51
>XP_005250138
          Length = 103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  AFCDAQ 6
          A+CDAQ
Sbjct: 46 AYCDAQ 51
>XP_005264726
          Length = 314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FCDAQSMQ 9
           FC +Q+MQ
Sbjct: 143 FCTSQAMQ 150
>XP_005276070
          Length = 103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  AFCDAQ 6
          A+CDAQ
Sbjct: 46 AYCDAQ 51
>NP_001180473
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1  AFCDAQSMQ 9
          A+CDA+ ++
Sbjct: 62 AYCDAKEIK 70
>NP_001146
          Length = 673

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AFCDAQSMQ 9
           A+CDA+ ++
Sbjct: 94  AYCDAKEIK 102
>XP_005268489
          Length = 667

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AFCDAQSMQ 9
           A+CDA+ ++
Sbjct: 94  AYCDAKEIK 102
>NP_003059
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 3   CDAQS 7
           CDAQS
Sbjct: 151 CDAQS 155
>NP_699193
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   FCDAQS 7
           +CDA+S
Sbjct: 338 YCDAES 343
>NP_001163894
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   FCDAQS 7
           +CDA+S
Sbjct: 338 YCDAES 343
>NP_001012977
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   FCDAQS 7
           +CDA+S
Sbjct: 664 YCDAES 669
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.121    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 496,983
Number of extensions: 451
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package