Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           20     299
NP_000242                                                              20     299
XP_005264389                                                           20     299
NP_001157750                                                           17    2528
NP_065838                                                              17    3301
XP_006721625                                                           17    3301
NP_002948                                                              17    4312
NP_001254645                                                           17    4312
XP_006722813                                                           17    4312
XP_006717295                                                           17    4312
XP_005263466                                                           17    4312
NP_002681                                                              16    5631
NP_689914                                                              16    5631
XP_005273594                                                           16    5631
XP_005273593                                                           16    5631
XP_005273592                                                           16    5631
NP_001180437                                                           16    7355
NP_005603                                                              16    7355
NP_003240                                                              16    7355
NP_597701                                                              16    7355
NP_001075949                                                           16    7355
NP_001074214                                                           16    7355
NP_001074213                                                           16    7355
NP_001248772                                                           16    7355
NP_001337                                                              16    7355
XP_006725158                                                           16    7355
XP_006716771                                                           16    7355
XP_005265817                                                           16    7355
NP_055604                                                              16    7355
NP_001030025                                                           15    9605
NP_000319                                                              15    9605
NP_060626                                                              15    9605
NP_056193                                                              15    9605
NP_001124443                                                           15    9605
NP_001138817                                                           15    9605
NP_001247421                                                           15    9605
NP_001247423                                                           15    9605
NP_001247422                                                           15    9605
NP_002897                                                              15    9605
NP_690873                                                              15    9605
NP_001166244                                                           15    9605
NP_001247424                                                           15    9605
NP_002285                                                              15    9605
NP_054701                                                              15    9605
NP_001116078                                                           15    9605
NP_031387                                                              15    9605
NP_053586                                                              15    9605
NP_852466                                                              15    9605
NP_001129145                                                           15    9605
NP_056936                                                              15    9605
NP_005611                                                              15    9605
NP_001138816                                                           15    9605
NP_116227                                                              15    9605
NP_001138815                                                           15    9605
NP_071769                                                              15    9605
XP_005272690                                                           15    9605
XP_006724601                                                           15    9605
XP_005259413                                                           15    9605
XP_006723511                                                           15    9605
XP_005259411                                                           15    9605
XP_006723510                                                           15    9605
XP_005258592                                                           15    9605
XP_005267464                                                           15    9605
XP_005267463                                                           15    9605
XP_006720142                                                           15    9605
XP_005267462                                                           15    9605
XP_005266119                                                           15    9605
XP_005265160                                                           15    9605
XP_006713189                                                           15    9605
XP_005265159                                                           15    9605
XP_006712135                                                           15    9605
XP_006712134                                                           15    9605
XP_006712133                                                           15    9605
NP_057581                                                              15    9605
NP_001025032                                                           15    9605
>NP_001245210
          Length = 868

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           AELANF KH
Sbjct: 765 AELANFPKH 773
>NP_000242
          Length = 934

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           AELANF KH
Sbjct: 831 AELANFPKH 839
>XP_005264389
          Length = 921

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           AELANF KH
Sbjct: 831 AELANFPKH 839
>NP_001157750
          Length = 451

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELANFTKH 9
           AEL  FT+H
Sbjct: 341 AELTGFTEH 349
>NP_065838
          Length = 865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LANFTKH 9
           +ANFT+H
Sbjct: 512 IANFTEH 518
>XP_006721625
          Length = 865

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LANFTKH 9
           +ANFT+H
Sbjct: 512 IANFTEH 518
>NP_002948
          Length = 462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LANFTKH 9
           +A+FTKH
Sbjct: 127 MASFTKH 133
>NP_001254645
          Length = 622

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           +++AN TKH
Sbjct: 518 SKVANLTKH 526
>XP_006722813
          Length = 594

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           +++AN TKH
Sbjct: 490 SKVANLTKH 498
>XP_006717295
          Length = 365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LANFTKH 9
          +A+FTKH
Sbjct: 30 MASFTKH 36
>XP_005263466
          Length = 435

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LANFTKH 9
           +A+FTKH
Sbjct: 100 MASFTKH 106
>NP_002681
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ELANFTKH 9
          ELANF K+
Sbjct: 21 ELANFEKN 28
>NP_689914
          Length = 5058

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/5 (100%), Positives = 5/5 (100%)

Query: 5   NFTKH 9
           NFTKH
Sbjct: 710 NFTKH 714
>XP_005273594
          Length = 306

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ELANFTKH 9
          ELANF K+
Sbjct: 21 ELANFEKN 28
>XP_005273593
          Length = 341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ELANFTKH 9
          ELANF K+
Sbjct: 21 ELANFEKN 28
>XP_005273592
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ELANFTKH 9
          ELANF K+
Sbjct: 21 ELANFEKN 28
>NP_001180437
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELANFTKH 9
           A+ +NF KH
Sbjct: 371 ADRSNFKKH 379
>NP_005603
          Length = 1097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELANFTKH 9
           A+ +NF KH
Sbjct: 371 ADRSNFKKH 379
>NP_003240
          Length = 689

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AELANFTK 8
           A +ANFTK
Sbjct: 447 AMVANFTK 454
>NP_597701
          Length = 670

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELANFTKH 9
           A LAN ++H
Sbjct: 510 ASLANLSRH 518
>NP_001075949
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           ++ +NFT+H
Sbjct: 317 SQTSNFTQH 325
>NP_001074214
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 467 ANFAKH 472
>NP_001074213
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 481 ANFAKH 486
>NP_001248772
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           ++ +NFT+H
Sbjct: 317 SQTSNFTQH 325
>NP_001337
          Length = 791

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 506 ANFAKH 511
>XP_006725158
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           ++ +NFT+H
Sbjct: 317 SQTSNFTQH 325
>XP_006716771
          Length = 496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           ++ +NFT+H
Sbjct: 317 SQTSNFTQH 325
>XP_005265817
          Length = 775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AELANFTKH 9
          A+ +NF KH
Sbjct: 49 ADRSNFKKH 57
>NP_055604
          Length = 536

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   AELANFTKH 9
           ++ +NFT+H
Sbjct: 357 SQTSNFTQH 365
>NP_001030025
          Length = 1152

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   LANFTKH 9
           L NFT H
Sbjct: 331 LENFTNH 337
>NP_000319
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   LANFTKH 9
           L NFT H
Sbjct: 331 LENFTNH 337
>NP_060626
          Length = 4363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ELANFTKH 9
            E A+FT+H
Sbjct: 1466 EEAHFTRH 1473
>NP_056193
          Length = 4388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    ELANFTKH 9
            E A+FT+H
Sbjct: 1466 EEAHFTRH 1473
>NP_001124443
          Length = 505

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 235 ANFRKH 240
>NP_001138817
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 268 SNFTRH 273
>NP_001247421
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AELANFT 7
           AELA FT
Sbjct: 419 AELAEFT 425
>NP_001247423
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AELANFT 7
           AELA FT
Sbjct: 283 AELAEFT 289
>NP_001247422
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AELANFT 7
           AELA FT
Sbjct: 419 AELAEFT 425
>NP_002897
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AELANFT 7
           AELA FT
Sbjct: 419 AELAEFT 425
>NP_690873
          Length = 533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 238 ANFMKH 243
>NP_001166244
          Length = 545

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 250 ANFMKH 255
>NP_001247424
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  AELANFT 7
          AELA FT
Sbjct: 72 AELAEFT 78
>NP_002285
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LANFTK 8
           +ANFTK
Sbjct: 99  IANFTK 104
>NP_054701
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LANFTK 8
           +ANFTK
Sbjct: 99  IANFTK 104
>NP_001116078
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LANFTK 8
           +ANFTK
Sbjct: 99  IANFTK 104
>NP_031387
          Length = 1375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANFT H
Sbjct: 657 ANFTAH 662
>NP_053586
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   LANFTKH 9
           + NF+KH
Sbjct: 386 MVNFSKH 392
>NP_852466
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 638 SNFTRH 643
>NP_001129145
          Length = 583

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 457 ANFIKH 462
>NP_056936
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   ELANFTKH 9
           +L+N T+H
Sbjct: 344 QLSNLTRH 351
>NP_005611
          Length = 105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ELANFTKH 9
          ELA FTK+
Sbjct: 46 ELAAFTKN 53
>NP_001138816
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 268 SNFTRH 273
>NP_116227
          Length = 418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 268 SNFTRH 273
>NP_001138815
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 269 SNFTRH 274
>NP_071769
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 457 ANFIKH 462
>XP_005272690
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   LANFTKH 9
           L NFT H
Sbjct: 331 LENFTNH 337
>XP_006724601
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   LANFTKH 9
           L NFT H
Sbjct: 331 LENFTNH 337
>XP_005259413
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 164 SNFTRH 169
>XP_006723511
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 164 SNFTRH 169
>XP_005259411
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 236 SNFTRH 241
>XP_006723510
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 269 SNFTRH 274
>XP_005258592
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 241 ANFMKH 246
>XP_005267464
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANFT H
Sbjct: 657 ANFTAH 662
>XP_005267463
          Length = 1354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANFT H
Sbjct: 684 ANFTAH 689
>XP_006720142
          Length = 1386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANFT H
Sbjct: 668 ANFTAH 673
>XP_005267462
          Length = 1402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANFT H
Sbjct: 684 ANFTAH 689
>XP_005266119
          Length = 475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 235 ANFRKH 240
>XP_005265160
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 433 SNFTRH 438
>XP_006713189
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 626 SNFTRH 631
>XP_005265159
          Length = 1031

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   ANFTKH 9
           +NFT+H
Sbjct: 638 SNFTRH 643
>XP_006712135
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 403 ANFIKH 408
>XP_006712134
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 439 ANFIKH 444
>XP_006712133
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4   ANFTKH 9
           ANF KH
Sbjct: 452 ANFIKH 457
>NP_057581
          Length = 128

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3  LANFTKH 9
          L NF KH
Sbjct: 63 LGNFEKH 69
>NP_001025032
          Length = 138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3  LANFTKH 9
          L NF KH
Sbjct: 62 LCNFCKH 68
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.317    0.122    0.347 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 488,290
Number of extensions: 769
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package