Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_996801                                                              18    1935
XP_006720106                                                           18    1935
NP_001129575                                                           17    4312
NP_573400                                                              17    4312
NP_008981                                                              17    4312
NP_597705                                                              17    4312
NP_001098714                                                           17    4312
XP_006723752                                                           17    4312
XP_006723751                                                           17    4312
XP_006723750                                                           17    4312
XP_006723749                                                           17    4312
XP_006723748                                                           17    4312
XP_006722401                                                           17    4312
XP_006722400                                                           17    4312
XP_006722399                                                           17    4312
XP_006722398                                                           17    4312
NP_002836                                                              17    4312
NP_776168                                                              16    5631
NP_001124429                                                           16    5631
NP_001129120                                                           16    5631
NP_573439                                                              16    5631
NP_573438                                                              16    5631
NP_001181930                                                           16    5631
NP_005695                                                              16    5631
NP_002835                                                              16    5631
XP_006725089                                                           16    5631
XP_006725088                                                           16    5631
XP_006725087                                                           16    5631
XP_006725085                                                           16    5631
XP_006725084                                                           16    5631
XP_006725083                                                           16    5631
XP_006725082                                                           16    5631
XP_006715604                                                           16    5631
XP_006715603                                                           16    5631
XP_005267143                                                           16    5631
XP_006715602                                                           16    5631
XP_005267142                                                           16    5631
XP_006715600                                                           16    5631
XP_005267139                                                           16    5631
XP_006715599                                                           16    5631
XP_006715598                                                           16    5631
XP_006710335                                                           16    5631
XP_006710334                                                           16    5631
XP_006710333                                                           16    5631
XP_006710332                                                           16    5631
NP_061720                                                              16    5631
NP_690005                                                              16    5631
NP_006068                                                              16    7355
NP_001182447                                                           16    7355
NP_004791                                                              16    7355
NP_001161354                                                           16    7355
NP_065070                                                              16    7355
XP_005269444                                                           16    7355
XP_005269441                                                           16    7355
XP_005269440                                                           16    7355
NP_001008844                                                           15    9605
NP_004406                                                              15    9605
NP_001275677                                                           15    9605
NP_473362                                                              15    9605
>NP_996801
          Length = 323

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AELAILSLW 9
           A+LAI +LW
Sbjct: 196 ADLAIFALW 204
>XP_006720106
          Length = 287

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AELAILSLW 9
           A+LAI +LW
Sbjct: 160 ADLAIFALW 168
>NP_001129575
          Length = 1108

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AEL +LS W
Sbjct: 196 AELELLSSW 204
>NP_573400
          Length = 1460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 149 AELAISTFW 157
>NP_008981
          Length = 1441

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 149 AELAISTFW 157
>NP_597705
          Length = 1099

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AEL +LS W
Sbjct: 194 AELELLSSW 202
>NP_001098714
          Length = 1465

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 143 AELAISTFW 151
>XP_006723752
          Length = 1387

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 86 AELAISTFW 94
>XP_006723751
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 75 AELAISTFW 83
>XP_006723750
          Length = 1427

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 75 AELAISTFW 83
>XP_006723749
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 86 AELAISTFW 94
>XP_006723748
          Length = 1437

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 86 AELAISTFW 94
>XP_006722401
          Length = 1432

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELAI + W
Sbjct: 81 AELAISTFW 89
>XP_006722400
          Length = 1469

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 143 AELAISTFW 151
>XP_006722399
          Length = 1477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 143 AELAISTFW 151
>XP_006722398
          Length = 1494

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 143 AELAISTFW 151
>NP_002836
          Length = 1452

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELAI + W
Sbjct: 143 AELAISTFW 151
>NP_776168
          Length = 832

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ELAILSLW 9
          E+A+L LW
Sbjct: 5  EVAVLLLW 12
>NP_001124429
          Length = 951

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ELAILSLW 9
          E+A+L LW
Sbjct: 5  EVAVLLLW 12
>NP_001129120
          Length = 1446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>NP_573439
          Length = 1436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>NP_573438
          Length = 1440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>NP_001181930
          Length = 1433

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>NP_005695
          Length = 1446

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>NP_002835
          Length = 1440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006725089
          Length = 845

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006725088
          Length = 866

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006725087
          Length = 869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006725085
          Length = 1375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ + W
Sbjct: 81 AELAVSTFW 89
>XP_006725084
          Length = 1375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ + W
Sbjct: 81 AELAVSTFW 89
>XP_006725083
          Length = 1439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006725082
          Length = 1445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715604
          Length = 869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715603
          Length = 869

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_005267143
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715602
          Length = 893

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_005267142
          Length = 1439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715600
          Length = 1445

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_005267139
          Length = 1464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715599
          Length = 1469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006715598
          Length = 1470

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 152 AELAVSTFW 160
>XP_006710335
          Length = 1370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ + W
Sbjct: 74 AELAVSTFW 82
>XP_006710334
          Length = 1292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>XP_006710333
          Length = 1439

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>XP_006710332
          Length = 1442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+ + W
Sbjct: 146 AELAVSTFW 154
>NP_061720
          Length = 4024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LAILSLW 9
           LA+L LW
Sbjct: 279 LAVLDLW 285
>NP_690005
          Length = 343

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AE+ IL +W
Sbjct: 249 AEMKILGVW 257
>NP_006068
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ S W
Sbjct: 11 AELAVGSRW 19
>NP_001182447
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ S W
Sbjct: 11 AELAVGSRW 19
>NP_004791
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LAILSLW 9
           +AIL+LW
Sbjct: 471 VAILALW 477
>NP_001161354
          Length = 1250

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+  +W
Sbjct: 290 AELALWMIW 298
>NP_065070
          Length = 1429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AELAILSLW 9
           AELA+  +W
Sbjct: 469 AELALWMIW 477
>XP_005269444
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ S W
Sbjct: 11 AELAVGSRW 19
>XP_005269441
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ S W
Sbjct: 11 AELAVGSRW 19
>XP_005269440
          Length = 482

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AELAILSLW 9
          AELA+ S W
Sbjct: 11 AELAVGSRW 19
>NP_001008844
          Length = 2272

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AILSLW 9
           AIL+LW
Sbjct: 532 AILALW 537
>NP_004406
          Length = 2871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   AILSLW 9
           AIL+LW
Sbjct: 532 AILALW 537
>NP_001275677
          Length = 604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LAILSLW 9
           LA+LS W
Sbjct: 509 LAVLSWW 515
>NP_473362
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LAILSLW 9
           LA+L++W
Sbjct: 418 LAVLAVW 424
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.132    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 367,226
Number of extensions: 419
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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