Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     299
NP_653080                                                              20     299
XP_005267292                                                           20     299
XP_005267291                                                           20     299
XP_005267290                                                           20     299
XP_006716749                                                           17    2528
NP_001277155                                                           16    5631
NP_001277156                                                           16    5631
NP_055998                                                              16    5631
NP_055178                                                              16    5631
NP_001264984                                                           16    5631
NP_001158136                                                           16    5631
NP_036608                                                              16    5631
NP_689997                                                              16    5631
XP_005266395                                                           16    5631
XP_006714675                                                           16    5631
XP_006714673                                                           16    5631
XP_006714672                                                           16    5631
XP_006714670                                                           16    5631
XP_006714669                                                           16    5631
XP_006714668                                                           16    5631
XP_006714667                                                           16    5631
XP_006714666                                                           16    5631
XP_005248555                                                           16    5631
XP_006714665                                                           16    5631
XP_006712045                                                           16    5631
NP_005137                                                              16    5631
NP_004940                                                              16    7355
NP_077740                                                              16    7355
NP_055661                                                              16    7355
NP_775866                                                              16    7355
NP_004860                                                              16    7355
NP_001640                                                              16    7355
NP_001002909                                                           16    7355
NP_002770                                                              16    7355
NP_001257894                                                           16    7355
NP_001257895                                                           16    7355
XP_005274557                                                           16    7355
XP_005258263                                                           16    7355
XP_006721846                                                           16    7355
XP_006721845                                                           16    7355
XP_006721844                                                           16    7355
XP_005251177                                                           16    7355
NP_714915                                                              15    9605
NP_006761                                                              15    9605
NP_891550                                                              15    9605
NP_001009960                                                           15    9605
NP_612503                                                              15    9605
NP_849188                                                              15    9605
NP_001129201                                                           15    9605
NP_001129204                                                           15    9605
NP_001008529                                                           15    9605
NP_001008528                                                           15    9605
NP_940932                                                              15    9605
NP_001167589                                                           15    9605
NP_976049                                                              15    9605
XP_005257441                                                           15    9605
XP_005257440                                                           15    9605
XP_005257439                                                           15    9605
XP_006716748                                                           15    9605
XP_005265386                                                           15    9605
>NP_005091
          Length = 1782

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AEKGATSDG 9
           AE+GATSDG
Sbjct: 592 AEEGATSDG 600
>NP_653080
          Length = 1684

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AEKGATSDG 9
           AE+GATSDG
Sbjct: 494 AEEGATSDG 502
>XP_005267292
          Length = 1677

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AEKGATSDG 9
           AE+GATSDG
Sbjct: 487 AEEGATSDG 495
>XP_005267291
          Length = 1684

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AEKGATSDG 9
           AE+GATSDG
Sbjct: 494 AEEGATSDG 502
>XP_005267290
          Length = 1782

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AEKGATSDG 9
           AE+GATSDG
Sbjct: 592 AEEGATSDG 600
>XP_006716749
          Length = 894

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          EKG T DG
Sbjct: 3  EKGVTEDG 10
>NP_001277155
          Length = 2417

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1409 ASEGAMSDG 1417
>NP_001277156
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1354 ASEGAMSDG 1362
>NP_055998
          Length = 2434

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1426 ASEGAMSDG 1434
>NP_055178
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KGATSD 8
           KGATSD
Sbjct: 434 KGATSD 439
>NP_001264984
          Length = 4432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KGATSD 8
           KGATSD
Sbjct: 287 KGATSD 292
>NP_001158136
          Length = 2623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1615 ASEGAMSDG 1623
>NP_036608
          Length = 290

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E GA SDG
Sbjct: 59 ESGADSDG 66
>NP_689997
          Length = 798

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKGATSDG 9
           E G TSDG
Sbjct: 443 ENGYTSDG 450
>XP_005266395
          Length = 4588

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   KGATSD 8
           KGATSD
Sbjct: 434 KGATSD 439
>XP_006714675
          Length = 2275

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1267 ASEGAMSDG 1275
>XP_006714673
          Length = 2362

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1354 ASEGAMSDG 1362
>XP_006714672
          Length = 2414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1406 ASEGAMSDG 1414
>XP_006714670
          Length = 2425

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1417 ASEGAMSDG 1425
>XP_006714669
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1421 ASEGAMSDG 1429
>XP_006714668
          Length = 2429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1421 ASEGAMSDG 1429
>XP_006714667
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1424 ASEGAMSDG 1432
>XP_006714666
          Length = 2432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1424 ASEGAMSDG 1432
>XP_005248555
          Length = 2626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1618 ASEGAMSDG 1626
>XP_006714665
          Length = 2651

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AEKGATSDG 9
            A +GA SDG
Sbjct: 1643 ASEGAMSDG 1651
>XP_006712045
          Length = 150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E GA SDG
Sbjct: 59 ESGADSDG 66
>NP_005137
          Length = 800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           E+G T+DG
Sbjct: 352 EQGGTADG 359
>NP_004940
          Length = 847

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE G TS+G
Sbjct: 484 AEVGTTSNG 492
>NP_077740
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE G TS+G
Sbjct: 484 AEVGTTSNG 492
>NP_055661
          Length = 1159

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKGATSDG 9
           E GAT DG
Sbjct: 743 ELGATMDG 750
>NP_775866
          Length = 1076

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EKGATSD 8
           EKG+T+D
Sbjct: 709 EKGSTAD 715
>NP_004860
          Length = 444

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKGATSDG 9
           EKG  SDG
Sbjct: 97  EKGNDSDG 104
>NP_001640
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   AEKGATSD 8
           AEK  TSD
Sbjct: 858 AEKAGTSD 865
>NP_001002909
          Length = 1502

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE+G + DG
Sbjct: 323 AEEGTSEDG 331
>NP_002770
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           A+ G+T DG
Sbjct: 978 AQAGSTEDG 986
>NP_001257894
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           A+ G+T DG
Sbjct: 978 AQAGSTEDG 986
>NP_001257895
          Length = 645

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           A+ G+T DG
Sbjct: 599 AQAGSTEDG 607
>XP_005274557
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   AEKGATSD 8
           AEK  TSD
Sbjct: 858 AEKAGTSD 865
>XP_005258263
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE G TS+G
Sbjct: 341 AEVGTTSNG 349
>XP_006721846
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE+G + DG
Sbjct: 245 AEEGTSEDG 253
>XP_006721845
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE+G + DG
Sbjct: 245 AEEGTSEDG 253
>XP_006721844
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AEKGATSDG 9
           AE+G + DG
Sbjct: 245 AEEGTSEDG 253
>XP_005251177
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   EKGATSDG 9
           E GAT DG
Sbjct: 595 ELGATMDG 602
>NP_714915
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   KGATSDG 9
           KG T DG
Sbjct: 105 KGVTEDG 111
>NP_006761
          Length = 520

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   EKGATSDG 9
           EKG+  DG
Sbjct: 227 EKGSKGDG 234
>NP_891550
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    KGATSDG 9
            KGA+ DG
Sbjct: 1746 KGASEDG 1752
>NP_001009960
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E+G T DG
Sbjct: 40 EQGLTGDG 47
>NP_612503
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E+G T DG
Sbjct: 40 EQGLTGDG 47
>NP_849188
          Length = 2400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   AEKGATSD 8
           +E+GA+SD
Sbjct: 527 SEEGASSD 534
>NP_001129201
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KGATSDG 9
           KG TS+G
Sbjct: 403 KGVTSEG 409
>NP_001129204
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KGATSDG 9
           KG TS+G
Sbjct: 436 KGVTSEG 442
>NP_001008529
          Length = 177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 123 EKGPSSEG 130
>NP_001008528
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 123 EKGPSSEG 130
>NP_940932
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 123 EKGPSSEG 130
>NP_001167589
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E+GA  DG
Sbjct: 79 EEGAAGDG 86
>NP_976049
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  EKGATSDG 9
          E+GA  DG
Sbjct: 79 EEGAAGDG 86
>XP_005257441
          Length = 213

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 166 EKGPSSEG 173
>XP_005257440
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 166 EKGPSSEG 173
>XP_005257439
          Length = 247

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKGATSDG 9
           EKG +S+G
Sbjct: 166 EKGPSSEG 173
>XP_006716748
          Length = 980

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 3   KGATSDG 9
           KG T DG
Sbjct: 105 KGVTEDG 111
>XP_005265386
          Length = 1907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    KGATSDG 9
            KGA+ DG
Sbjct: 1718 KGASEDG 1724
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287    0.112    0.287 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 594,030
Number of extensions: 1376
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package