Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001261                                                              19     665
NP_001262                                                              19     665
XP_005271924                                                           19     665
XP_005271923                                                           19     665
NP_001138462                                                           17    4312
NP_058633                                                              17    4312
XP_006726390                                                           17    4312
XP_006726389                                                           17    4312
XP_006726388                                                           17    4312
XP_006726387                                                           17    4312
XP_006724562                                                           17    4312
XP_005274609                                                           17    4312
XP_006711142                                                           17    4312
XP_006711141                                                           17    4312
XP_006711140                                                           17    4312
XP_006710131                                                           17    4312
XP_006710130                                                           17    4312
XP_006710129                                                           17    4312
XP_006710128                                                           17    4312
XP_006712175                                                           16    5631
XP_005264643                                                           16    5631
XP_006712174                                                           16    5631
NP_115494                                                              16    5631
NP_055761                                                              16    7355
NP_955468                                                              16    7355
NP_653259                                                              16    7355
XP_005262425                                                           16    7355
XP_005264573                                                           16    7355
NP_036525                                                              16    7355
NP_008986                                                              15    9605
NP_000245                                                              15    9605
NP_775267                                                              15    9605
NP_775268                                                              15    9605
NP_775266                                                              15    9605
NP_004094                                                              15    9605
NP_001271270                                                           15    9605
NP_078613                                                              15    9605
NP_001847                                                              15    9605
NP_112598                                                              15    9605
NP_001032251                                                           15    9605
NP_036229                                                              15    9605
NP_009201                                                              15    9605
XP_005261936                                                           15    9605
XP_005261935                                                           15    9605
XP_005261934                                                           15    9605
XP_005261933                                                           15    9605
XP_006717660                                                           15    9605
XP_005273505                                                           15    9605
XP_005273504                                                           15    9605
XP_006711832                                                           15    9605
XP_005273200                                                           15    9605
XP_005273198                                                           15    9605
XP_005270538                                                           15    9605
NP_055691                                                              15    9605
NP_817114                                                              15    9605
NP_004176                                                              15    9605
>NP_001261
          Length = 1710

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AEIRRFIK
Sbjct: 1129 AEIRRFIK 1136
>NP_001262
          Length = 1828

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AEIRRFIK
Sbjct: 1134 AEIRRFIK 1141
>XP_005271924
          Length = 1710

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AEIRRFIK
Sbjct: 1129 AEIRRFIK 1136
>XP_005271923
          Length = 1798

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AEIRRFIK
Sbjct: 1129 AEIRRFIK 1136
>NP_001138462
          Length = 1742

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEIRRFIKI 9
           A I RF+KI
Sbjct: 264 ANIERFVKI 272
>NP_058633
          Length = 1462

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EIRRFIK 8
            +IRRFIK
Sbjct: 1333 DIRRFIK 1339
>XP_006726390
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1031 AELRRFLR 1038
>XP_006726389
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1149 AELRRFLR 1156
>XP_006726388
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1167 AELRRFLR 1174
>XP_006726387
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1215 AELRRFLR 1222
>XP_006724562
          Length = 1326

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EIRRFIK 8
            +IRRFIK
Sbjct: 1197 DIRRFIK 1203
>XP_005274609
          Length = 1468

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EIRRFIK 8
            +IRRFIK
Sbjct: 1339 DIRRFIK 1345
>XP_006711142
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1149 AELRRFLR 1156
>XP_006711141
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1167 AELRRFLR 1174
>XP_006711140
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1215 AELRRFLR 1222
>XP_006710131
          Length = 1353

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1031 AELRRFLR 1038
>XP_006710130
          Length = 1471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1149 AELRRFLR 1156
>XP_006710129
          Length = 1489

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1167 AELRRFLR 1174
>XP_006710128
          Length = 1497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AEIRRFIK 8
            AE+RRF++
Sbjct: 1215 AELRRFLR 1222
>XP_006712175
          Length = 170

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEIRRFIKI 9
           AEIRRF  +
Sbjct: 162 AEIRRFSSV 170
>XP_005264643
          Length = 334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEIRRFIKI 9
           AEIRRF  +
Sbjct: 326 AEIRRFSSV 334
>XP_006712174
          Length = 349

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEIRRFIKI 9
           AEIRRF  +
Sbjct: 341 AEIRRFSSV 349
>NP_115494
          Length = 334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AEIRRFIKI 9
           AEIRRF  +
Sbjct: 326 AEIRRFSSV 334
>NP_055761
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AEIRRFIK 8
           A +RRFIK
Sbjct: 495 AVLRRFIK 502
>NP_955468
          Length = 584

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AEIRRFIK 8
           A +RRFIK
Sbjct: 463 AVLRRFIK 470
>NP_653259
          Length = 2073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1 AEIRRFIK 8
         AE+R+F K
Sbjct: 2 AEVRKFTK 9
>XP_005262425
          Length = 2086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1 AEIRRFIK 8
         AE+R+F K
Sbjct: 2 AEVRKFTK 9
>XP_005264573
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AEIRRFIK 8
           A +RRFIK
Sbjct: 494 AVLRRFIK 501
>NP_036525
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AEIRRFIK 8
            AE+RRF K
Sbjct: 1141 AELRRFRK 1148
>NP_008986
          Length = 1390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EIRRFIK 8
           EI++FIK
Sbjct: 968 EIKKFIK 974
>NP_000245
          Length = 1265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AE+R FI+I
Sbjct: 265 AEMRPFIEI 273
>NP_775267
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>NP_775268
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>NP_775266
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>NP_004094
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>NP_001271270
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RRFIKI 9
           RRF+KI
Sbjct: 159 RRFVKI 164
>NP_078613
          Length = 391

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IRRFIKI 9
           +RRF+K+
Sbjct: 229 VRRFLKL 235
>NP_001847
          Length = 1604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EIRRFIK 8
            EI+RFI+
Sbjct: 1438 EIKRFIR 1444
>NP_112598
          Length = 5088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           AE+RR+++
Sbjct: 275 AEVRRYLE 282
>NP_001032251
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AEI +F+K+
Sbjct: 99  AEISQFLKL 107
>NP_036229
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AEI +F+K+
Sbjct: 136 AEISQFLKL 144
>NP_009201
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RRFIKI 9
           RRF+KI
Sbjct: 106 RRFVKI 111
>XP_005261936
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           +E+R+F+K
Sbjct: 167 SELRKFLK 174
>XP_005261935
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           +E+R+F+K
Sbjct: 167 SELRKFLK 174
>XP_005261934
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           +E+R+F+K
Sbjct: 167 SELRKFLK 174
>XP_005261933
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           +E+R+F+K
Sbjct: 167 SELRKFLK 174
>XP_006717660
          Length = 1369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   EIRRFIK 8
           EI++FIK
Sbjct: 947 EIKKFIK 953
>XP_005273505
          Length = 997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>XP_005273504
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   EIRRFIK 8
           E+RRF K
Sbjct: 182 ELRRFFK 188
>XP_006711832
          Length = 1139

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AE+R FI+I
Sbjct: 265 AEMRPFIEI 273
>XP_005273200
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AE+R FI+I
Sbjct: 265 AEMRPFIEI 273
>XP_005273198
          Length = 1264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AE+R FI+I
Sbjct: 264 AEMRPFIEI 272
>XP_005270538
          Length = 1588

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    EIRRFIK 8
            EI+RFI+
Sbjct: 1422 EIKRFIR 1428
>NP_055691
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   AEIRRFIK 8
           +E+R+F+K
Sbjct: 167 SELRKFLK 174
>NP_817114
          Length = 142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AEIRRFIKI 9
           AEI +F+K+
Sbjct: 99  AEISQFLKL 107
>NP_004176
          Length = 372

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   IRRFIKI 9
           +RRF+K+
Sbjct: 210 VRRFLKL 216
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.348    0.160    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 358,590
Number of extensions: 536
Number of successful extensions: 56
Number of sequences better than 10000.0: 56
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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