Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              18    1482
XP_006715292                                                           18    1482
NP_001245215                                                           17    3301
NP_001269358                                                           17    3301
NP_001245216                                                           17    3301
NP_775785                                                              17    3301
XP_006714605                                                           17    3301
XP_006714604                                                           17    3301
XP_006714603                                                           17    3301
XP_006714602                                                           17    3301
XP_006714601                                                           17    3301
XP_006714600                                                           17    3301
NP_055873                                                              17    4312
XP_006719854                                                           17    4312
XP_006719853                                                           17    4312
NP_000154                                                              16    5631
NP_001229329                                                           16    5631
NP_001229335                                                           16    5631
NP_001229332                                                           16    5631
NP_001229333                                                           16    5631
NP_001229330                                                           16    5631
NP_001229331                                                           16    5631
NP_001229389                                                           16    5631
NP_001229334                                                           16    5631
NP_001229328                                                           16    5631
XP_005248345                                                           16    5631
NP_006382                                                              16    7355
NP_001136105                                                           16    7355
NP_055123                                                              16    7355
NP_006381                                                              16    7355
NP_003588                                                              16    7355
NP_001171187                                                           16    7355
NP_001171189                                                           16    7355
NP_786951                                                              16    7355
XP_005256637                                                           16    7355
XP_005256636                                                           16    7355
XP_005246236                                                           16    7355
NP_001177924                                                           16    7355
NP_001129476                                                           15    9605
NP_001116203                                                           15    9605
NP_056056                                                              15    9605
NP_002239                                                              15    9605
NP_006853                                                              15    9605
NP_001077434                                                           15    9605
NP_001077433                                                           15    9605
NP_001077432                                                           15    9605
XP_005261319                                                           15    9605
XP_006724151                                                           15    9605
XP_006724150                                                           15    9605
XP_006724149                                                           15    9605
XP_006724148                                                           15    9605
XP_006724147                                                           15    9605
XP_006724146                                                           15    9605
XP_006724145                                                           15    9605
XP_006724144                                                           15    9605
XP_005259964                                                           15    9605
XP_005259963                                                           15    9605
XP_005259962                                                           15    9605
XP_005244913                                                           15    9605
XP_005244911                                                           15    9605
XP_005244910                                                           15    9605
>NP_115927
          Length = 1321

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A TDALLST
Sbjct: 313 AGTDALLST 321
>XP_006715292
          Length = 759

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A TDALLST
Sbjct: 300 AGTDALLST 308
>NP_001245215
          Length = 498

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 177 DTDTILST 184
>NP_001269358
          Length = 437

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 116 DTDTILST 123
>NP_001245216
          Length = 498

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 213 DTDTILST 220
>NP_775785
          Length = 561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714605
          Length = 496

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714604
          Length = 531

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714603
          Length = 561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714602
          Length = 561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714601
          Length = 561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>XP_006714600
          Length = 561

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           DTD +LST
Sbjct: 240 DTDTILST 247
>NP_055873
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ADTDALLS 8
            +DTDALL+
Sbjct: 1485 SDTDALLA 1492
>XP_006719854
          Length = 1550

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ADTDALLS 8
            +DTDALL+
Sbjct: 1130 SDTDALLA 1137
>XP_006719853
          Length = 1809

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    ADTDALLS 8
            +DTDALL+
Sbjct: 1389 SDTDALLA 1396
>NP_000154
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229329
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229335
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229332
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229333
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229330
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229331
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229389
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 338 SDTDRLLSS 346
>NP_001229334
          Length = 638

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 360 SDTDRLLSS 368
>NP_001229328
          Length = 645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 367 SDTDRLLSS 375
>XP_005248345
          Length = 616

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           +DTD LLS+
Sbjct: 338 SDTDRLLSS 346
>NP_006382
          Length = 1038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DTDALLS 8
           DTD LLS
Sbjct: 704 DTDTLLS 710
>NP_001136105
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A+ D+LLST
Sbjct: 341 AERDSLLST 349
>NP_055123
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A+ D+LLST
Sbjct: 341 AERDSLLST 349
>NP_006381
          Length = 1037

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DTDALLS 8
           DTD LLS
Sbjct: 704 DTDTLLS 710
>NP_003588
          Length = 512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TDALLST 9
           TD+LLST
Sbjct: 220 TDSLLST 226
>NP_001171187
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TDALLST 9
           TD+LLST
Sbjct: 203 TDSLLST 209
>NP_001171189
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TDALLST 9
           TD+LLST
Sbjct: 203 TDSLLST 209
>NP_786951
          Length = 214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           + DALLST
Sbjct: 197 EADALLST 204
>XP_005256637
          Length = 879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A+ D+LLST
Sbjct: 341 AERDSLLST 349
>XP_005256636
          Length = 880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADTDALLST 9
           A+ D+LLST
Sbjct: 341 AERDSLLST 349
>XP_005246236
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   TDALLST 9
           TD+LLST
Sbjct: 203 TDSLLST 209
>NP_001177924
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   DTDALLS 8
           DTD LLS
Sbjct: 499 DTDTLLS 505
>NP_001129476
          Length = 1073

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_001116203
          Length = 966

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_056056
          Length = 2002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>NP_002239
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ADTDALLS 8
           AD D LLS
Sbjct: 224 ADVDVLLS 231
>NP_006853
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_001077434
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 515 ETDASLST 522
>NP_001077433
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 470 ETDASLST 477
>NP_001077432
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 515 ETDASLST 522
>XP_005261319
          Length = 2002

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724151
          Length = 2063

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724150
          Length = 2154

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724149
          Length = 2168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724148
          Length = 2176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724147
          Length = 2187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724146
          Length = 2193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724145
          Length = 2210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_006724144
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ADTDALLS 8
           ADT+ LLS
Sbjct: 319 ADTELLLS 326
>XP_005259964
          Length = 623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ADTDALLS 8
           AD D LLS
Sbjct: 307 ADVDVLLS 314
>XP_005259963
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ADTDALLS 8
           AD D LLS
Sbjct: 307 ADVDVLLS 314
>XP_005259962
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ADTDALLS 8
           AD D LLS
Sbjct: 307 ADVDVLLS 314
>XP_005244913
          Length = 337

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 291 ETDASLST 298
>XP_005244911
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 515 ETDASLST 522
>XP_005244910
          Length = 561

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DTDALLST 9
           +TDA LST
Sbjct: 515 ETDASLST 522
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.115    0.282 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 464,889
Number of extensions: 715
Number of successful extensions: 61
Number of sequences better than 10000.0: 61
Number of HSP's gapped: 61
Number of HSP's successfully gapped: 61
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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