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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              18    1135
NP_001091680                                                           18    1135
NP_001091679                                                           18    1135
XP_006713048                                                           18    1135
XP_005264943                                                           18    1135
NP_001230115                                                           17    4312
NP_000375                                                              16    5631
NP_001035232                                                           16    5631
NP_066287                                                              16    5631
NP_001035233                                                           16    5631
XP_005270302                                                           16    5631
XP_005246813                                                           16    5631
XP_005246812                                                           16    5631
XP_005246811                                                           16    5631
XP_005246810                                                           16    5631
XP_005246808                                                           16    5631
XP_005246807                                                           16    5631
NP_036387                                                              16    7355
NP_002788                                                              15    9605
NP_001138404                                                           15    9605
XP_005267928                                                           15    9605

>NP_001895
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ADLMELGMA 9
          ADLMEL MA
Sbjct: 5  ADLMELDMA 13



>NP_001091680
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ADLMELGMA 9
          ADLMEL MA
Sbjct: 5  ADLMELDMA 13



>NP_001091679
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ADLMELGMA 9
          ADLMEL MA
Sbjct: 5  ADLMELDMA 13



>XP_006713048
          Length = 720

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ADLMELGMA 9
          ADLMEL MA
Sbjct: 5  ADLMELDMA 13



>XP_005264943
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  ADLMELGMA 9
          ADLMEL MA
Sbjct: 5  ADLMELDMA 13



>NP_001230115
          Length = 404

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ADLMELGM 8
          AD++E+GM
Sbjct: 85 ADILEVGM 92



>NP_000375
          Length = 4563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   ADLMELGM 8
           ADL+E+G+
Sbjct: 685 ADLIEIGL 692



>NP_001035232
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>NP_066287
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>NP_001035233
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>XP_005270302
          Length = 105

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  ADLMELGM 8
          AD+M+LG+
Sbjct: 8  ADMMDLGI 15



>XP_005246813
          Length = 1271

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 101 LMELGLA 107



>XP_005246812
          Length = 1754

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 584 LMELGLA 590



>XP_005246811
          Length = 1995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 825 LMELGLA 831



>XP_005246810
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>XP_005246808
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>XP_005246807
          Length = 2005

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LMELGMA 9
           LMELG+A
Sbjct: 835 LMELGLA 841



>NP_036387
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   ADLMELGMA 9
           ADL+ LG+A
Sbjct: 234 ADLIMLGLA 242



>NP_002788
          Length = 263

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ADLMELG 7
          ADL++LG
Sbjct: 25 ADLLDLG 31



>NP_001138404
          Length = 203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ADLMELG 7
          ADL++LG
Sbjct: 25 ADLLDLG 31



>XP_005267928
          Length = 169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ADLMELG 7
          ADL++LG
Sbjct: 25 ADLLDLG 31



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.134    0.349 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 438,173
Number of extensions: 794
Number of successful extensions: 21
Number of sequences better than 10000.0: 21
Number of HSP's gapped: 21
Number of HSP's successfully gapped: 21
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)