Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004110                                                              20     299
NP_001243599                                                           17    2528
NP_569710                                                              17    2528
NP_005691                                                              17    2528
NP_003747                                                              17    4312
NP_079350                                                              16    5631
NP_001159605                                                           16    5631
NP_001171809                                                           16    5631
NP_001098713                                                           16    5631
NP_065817                                                              16    5631
NP_001136026                                                           16    5631
NP_789792                                                              16    5631
NP_001129507                                                           16    5631
NP_060192                                                              16    5631
XP_005260040                                                           16    5631
XP_006718281                                                           16    5631
XP_006714380                                                           16    5631
XP_006714379                                                           16    5631
XP_006714378                                                           16    5631
XP_006714377                                                           16    5631
NP_079255                                                              16    7355
NP_079229                                                              16    7355
XP_005268373                                                           16    7355
XP_005253995                                                           16    7355
XP_006719669                                                           16    7355
NP_004534                                                              15    9605
NP_001258137                                                           15    9605
NP_001157980                                                           15    9605
NP_001157979                                                           15    9605
NP_036337                                                              15    9605
NP_060613                                                              15    9605
XP_005246675                                                           15    9605
XP_005246674                                                           15    9605
XP_005246672                                                           15    9605
XP_005246670                                                           15    9605
XP_005246669                                                           15    9605
XP_005246668                                                           15    9605
XP_005246667                                                           15    9605
XP_005246665                                                           15    9605
XP_006712605                                                           15    9605
XP_006712604                                                           15    9605
XP_005246663                                                           15    9605
XP_005246660                                                           15    9605
XP_005246661                                                           15    9605
XP_005246659                                                           15    9605
XP_005246658                                                           15    9605
XP_005246657                                                           15    9605
XP_005246656                                                           15    9605
XP_005246655                                                           15    9605
XP_005246654                                                           15    9605
XP_005246653                                                           15    9605
XP_005246652                                                           15    9605
XP_005246649                                                           15    9605
XP_005246651                                                           15    9605
XP_005246650                                                           15    9605
XP_005246648                                                           15    9605
XP_005246647                                                           15    9605
XP_005264287                                                           15    9605
>NP_004110
          Length = 993

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ADAEEVMYQ 9
           ADAEE MYQ
Sbjct: 948 ADAEEAMYQ 956
>NP_001243599
          Length = 707

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ADAEEVMY 8
           ADAE+V+Y
Sbjct: 503 ADAEDVIY 510
>NP_569710
          Length = 737

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ADAEEVMY 8
           ADAE+V+Y
Sbjct: 533 ADAEDVIY 540
>NP_005691
          Length = 737

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   ADAEEVMY 8
           ADAE+V+Y
Sbjct: 533 ADAEDVIY 540
>NP_003747
          Length = 352

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ADAEEVMYQ 9
           AD +EV YQ
Sbjct: 92  ADFDEVQYQ 100
>NP_079350
          Length = 4012

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1360 ASAEEIIYK 1368
>NP_001159605
          Length = 1976

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1360 ASAEEIIYK 1368
>NP_001171809
          Length = 1148

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    ADAEEVMYQ 9
            AD+E+VM++
Sbjct: 1116 ADSEKVMHE 1124
>NP_001098713
          Length = 1101

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    ADAEEVMYQ 9
            AD+E+VM++
Sbjct: 1069 ADSEKVMHE 1077
>NP_065817
          Length = 1100

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    ADAEEVMYQ 9
            AD+E+VM++
Sbjct: 1068 ADSEKVMHE 1076
>NP_001136026
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ADAEEVMYQ 9
           ADA  +MYQ
Sbjct: 211 ADARMLMYQ 219
>NP_789792
          Length = 1093

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EEVMYQ 9
           EE+MYQ
Sbjct: 245 EEIMYQ 250
>NP_001129507
          Length = 659

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ADAEEVMYQ 9
           ADA  +MYQ
Sbjct: 211 ADARMLMYQ 219
>NP_060192
          Length = 659

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ADAEEVMYQ 9
           ADA  +MYQ
Sbjct: 211 ADARMLMYQ 219
>XP_005260040
          Length = 630

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ADAEEVMYQ 9
           ADA  +MYQ
Sbjct: 211 ADARMLMYQ 219
>XP_006718281
          Length = 983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   EEVMYQ 9
           EE+MYQ
Sbjct: 135 EEIMYQ 140
>XP_006714380
          Length = 3897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1360 ASAEEIIYK 1368
>XP_006714379
          Length = 3936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1360 ASAEEIIYK 1368
>XP_006714378
          Length = 3965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1313 ASAEEIIYK 1321
>XP_006714377
          Length = 4010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            A AEE++Y+
Sbjct: 1360 ASAEEIIYK 1368
>NP_079255
          Length = 1123

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ADAEEVMYQ 9
          A A+E+M+Q
Sbjct: 22 AGADEIMHQ 30
>NP_079229
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DAEEVMYQ 9
           D EE+M+Q
Sbjct: 347 DPEELMFQ 354
>XP_005268373
          Length = 984

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  ADAEEVMYQ 9
          A A+E+M+Q
Sbjct: 22 AGADEIMHQ 30
>XP_005253995
          Length = 836

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DAEEVMYQ 9
           D EE+M+Q
Sbjct: 211 DPEELMFQ 218
>XP_006719669
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DAEEVMYQ 9
           D EE+M+Q
Sbjct: 319 DPEELMFQ 326
>NP_004534
          Length = 6669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 6624 ADADEVSFK 6632
>NP_001258137
          Length = 8560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8515 ADADEVSFK 8523
>NP_001157980
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8480 ADADEVSFK 8488
>NP_001157979
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8480 ADADEVSFK 8488
>NP_036337
          Length = 286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  DAEEVMYQ 9
          + EEV YQ
Sbjct: 50 EGEEVFYQ 57
>NP_060613
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   DAEEVMYQ 9
           D+EEV+++
Sbjct: 261 DSEEVLFE 268
>XP_005246675
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 5178 ADADEVSFK 5186
>XP_005246674
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 7508 ADADEVSFK 7516
>XP_005246672
          Length = 8277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8232 ADADEVSFK 8240
>XP_005246670
          Length = 8282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8237 ADADEVSFK 8245
>XP_005246669
          Length = 8282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8237 ADADEVSFK 8245
>XP_005246668
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8263 ADADEVSFK 8271
>XP_005246667
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8263 ADADEVSFK 8271
>XP_005246665
          Length = 8339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8294 ADADEVSFK 8302
>XP_006712605
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8325 ADADEVSFK 8333
>XP_006712604
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8325 ADADEVSFK 8333
>XP_005246663
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8325 ADADEVSFK 8333
>XP_005246660
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8325 ADADEVSFK 8333
>XP_005246661
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8325 ADADEVSFK 8333
>XP_005246659
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8356 ADADEVSFK 8364
>XP_005246658
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8356 ADADEVSFK 8364
>XP_005246657
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8387 ADADEVSFK 8395
>XP_005246656
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8387 ADADEVSFK 8395
>XP_005246655
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8418 ADADEVSFK 8426
>XP_005246654
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8418 ADADEVSFK 8426
>XP_005246653
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8418 ADADEVSFK 8426
>XP_005246652
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005246649
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005246651
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005246650
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005246648
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005246647
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    ADAEEVMYQ 9
            ADA+EV ++
Sbjct: 8449 ADADEVSFK 8457
>XP_005264287
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  DAEEVMYQ 9
          + EEV YQ
Sbjct: 50 EGEEVFYQ 57
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.118    0.295 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 509,712
Number of extensions: 585
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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