Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              19     869
XP_005265800                                                           19     869
XP_006714103                                                           19     869
XP_006714102                                                           19     869
NP_005624                                                              17    3301
XP_005264572                                                           17    3301
NP_001193972                                                           17    3301
NP_001005619                                                           17    4312
NP_001005731                                                           17    4312
NP_000204                                                              17    4312
NP_001001924                                                           17    4312
NP_001001925                                                           17    4312
NP_065136                                                              17    4312
NP_689777                                                              17    4312
NP_060360                                                              17    4312
NP_982354                                                              17    4312
NP_001182131                                                           17    4312
XP_005257369                                                           17    4312
XP_005257368                                                           17    4312
XP_006721933                                                           17    4312
XP_006721931                                                           17    4312
XP_006721930                                                           17    4312
XP_005257366                                                           17    4312
XP_006721929                                                           17    4312
XP_005266465                                                           17    4312
XP_005266464                                                           17    4312
XP_005266463                                                           17    4312
XP_006719241                                                           17    4312
XP_005250858                                                           17    4312
XP_005250857                                                           17    4312
XP_005273640                                                           17    4312
XP_005273639                                                           17    4312
XP_005273638                                                           17    4312
XP_005273637                                                           17    4312
XP_005273636                                                           17    4312
XP_005273635                                                           17    4312
XP_005273634                                                           17    4312
NP_006387                                                              16    5631
NP_006242                                                              16    7355
NP_996879                                                              16    7355
NP_996790                                                              16    7355
NP_001034842                                                           16    7355
NP_055127                                                              16    7355
NP_115942                                                              16    7355
XP_006718869                                                           16    7355
XP_006714545                                                           16    7355
XP_006714544                                                           16    7355
XP_006710494                                                           16    7355
XP_006710492                                                           16    7355
XP_006710491                                                           16    7355
XP_006710490                                                           16    7355
XP_006710489                                                           16    7355
NP_065979                                                              15    9605
NP_871626                                                              15    9605
NP_000244                                                              15    9605
NP_003105                                                              15    9605
NP_002709                                                              15    9605
NP_757367                                                              15    9605
NP_056338                                                              15    9605
NP_001177376                                                           15    9605
NP_065934                                                              15    9605
XP_005260080                                                           15    9605
XP_006716683                                                           15    9605
XP_006716682                                                           15    9605
XP_005263082                                                           15    9605
XP_006713749                                                           15    9605
>NP_006197
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           A MRVDSDN
Sbjct: 978 ARMRVDSDN 986
>XP_005265800
          Length = 1089

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           A MRVDSDN
Sbjct: 978 ARMRVDSDN 986
>XP_006714103
          Length = 1111

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ACMRVDSDN 9
            A MRVDSDN
Sbjct: 1000 ARMRVDSDN 1008
>XP_006714102
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    ACMRVDSDN 9
            A MRVDSDN
Sbjct: 1003 ARMRVDSDN 1011
>NP_005624
          Length = 1333

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CMRVDSD 8
           C+RV+SD
Sbjct: 980 CLRVESD 986
>XP_005264572
          Length = 1318

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CMRVDSD 8
           C+RV+SD
Sbjct: 980 CLRVESD 986
>NP_001193972
          Length = 189

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   CMRVDSD 8
           C+R+DSD
Sbjct: 132 CVRLDSD 138
>NP_001005619
          Length = 1805

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>NP_001005731
          Length = 1752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>NP_000204
          Length = 1822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>NP_001001924
          Length = 1270

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>NP_001001925
          Length = 1216

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>NP_065136
          Length = 1203

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ACMRVDS 7
          AC+R+DS
Sbjct: 14 ACLRLDS 20
>NP_689777
          Length = 3997

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ACMRVDS 7
            AC RVDS
Sbjct: 2438 ACTRVDS 2444
>NP_060360
          Length = 4022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ACMRVDS 7
            AC RVDS
Sbjct: 2463 ACTRVDS 2469
>NP_982354
          Length = 1237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ACMRVDS 7
          AC+R+DS
Sbjct: 14 ACLRLDS 20
>NP_001182131
          Length = 137

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   MRVDSDN 9
           MRVDSD+
Sbjct: 108 MRVDSDS 114
>XP_005257369
          Length = 1752

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>XP_005257368
          Length = 1875

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>XP_006721933
          Length = 1787

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 76 CVRVDKD 82
>XP_006721931
          Length = 1840

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 76 CVRVDKD 82
>XP_006721930
          Length = 1857

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 76 CVRVDKD 82
>XP_005257366
          Length = 1875

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 41 CVRVDKD 47
>XP_006721929
          Length = 1910

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  CMRVDSD 8
          C+RVD D
Sbjct: 76 CVRVDKD 82
>XP_005266465
          Length = 1019

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ACMRVDS 7
          AC+R+DS
Sbjct: 14 ACLRLDS 20
>XP_005266464
          Length = 1161

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ACMRVDS 7
          AC+R+DS
Sbjct: 14 ACLRLDS 20
>XP_005266463
          Length = 1195

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  ACMRVDS 7
          AC+R+DS
Sbjct: 14 ACLRLDS 20
>XP_006719241
          Length = 344

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           AC R DSD
Sbjct: 256 ACTRPDSD 263
>XP_005250858
          Length = 4022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ACMRVDS 7
            AC RVDS
Sbjct: 2463 ACTRVDS 2469
>XP_005250857
          Length = 4022

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    ACMRVDS 7
            AC RVDS
Sbjct: 2463 ACTRVDS 2469
>XP_005273640
          Length = 969

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273639
          Length = 1216

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273638
          Length = 1228

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273637
          Length = 1228

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273636
          Length = 1270

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273635
          Length = 1282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>XP_005273634
          Length = 1282

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ACMRVDSDN 9
           +C+R +SDN
Sbjct: 734 SCLRRNSDN 742
>NP_006387
          Length = 199

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  ACMRVDSD 8
          AC  +DSD
Sbjct: 72 ACQELDSD 79
>NP_006242
          Length = 559

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           +C R DSD
Sbjct: 502 SCQRSDSD 509
>NP_996879
          Length = 2223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    CMRVDS 7
            CMRV+S
Sbjct: 1490 CMRVES 1495
>NP_996790
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           +C R DSD
Sbjct: 517 SCQRSDSD 524
>NP_001034842
          Length = 1958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           AC+  DSD
Sbjct: 110 ACLAFDSD 117
>NP_055127
          Length = 327

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   CMRVDS 7
           CMR DS
Sbjct: 297 CMRADS 302
>NP_115942
          Length = 333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 2  CMRVDSDN 9
          C R D DN
Sbjct: 7  CTRPDGDN 14
>XP_006718869
          Length = 270

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 2   CMRVDS 7
           CMR DS
Sbjct: 240 CMRADS 245
>XP_006714545
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           +C R DSD
Sbjct: 244 SCQRSDSD 251
>XP_006714544
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   ACMRVDSD 8
           +C R DSD
Sbjct: 401 SCQRSDSD 408
>XP_006710494
          Length = 1152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CMRVDS 7
           CMRV+S
Sbjct: 419 CMRVES 424
>XP_006710492
          Length = 1351

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CMRVDS 7
           CMRV+S
Sbjct: 618 CMRVES 623
>XP_006710491
          Length = 1496

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   CMRVDS 7
           CMRV+S
Sbjct: 763 CMRVES 768
>XP_006710490
          Length = 2158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    CMRVDS 7
            CMRV+S
Sbjct: 1425 CMRVES 1430
>XP_006710489
          Length = 2185

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    CMRVDS 7
            CMRV+S
Sbjct: 1452 CMRVES 1457
>NP_065979
          Length = 1215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ACMRVDS 7
           AC RVD+
Sbjct: 569 ACARVDA 575
>NP_871626
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   CMRVDSD 8
           CM VD D
Sbjct: 362 CMDVDGD 368
>NP_000244
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           CM++D D
Sbjct: 827 CMQMDKD 833
>NP_003105
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           C+++D D
Sbjct: 170 CLKIDED 176
>NP_002709
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   CMRVDSD 8
           CM VD D
Sbjct: 983 CMDVDGD 989
>NP_757367
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           C+++D D
Sbjct: 170 CLKIDED 176
>NP_056338
          Length = 237

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  ACMRVDSD 8
          AC+  DSD
Sbjct: 64 ACLITDSD 71
>NP_001177376
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   CMRVDSD 8
           CM VD D
Sbjct: 247 CMDVDGD 253
>NP_065934
          Length = 1185

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ACMRVDS 7
           AC RVD+
Sbjct: 542 ACARVDA 548
>XP_005260080
          Length = 1106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   ACMRVDS 7
           AC RVD+
Sbjct: 467 ACARVDT 473
>XP_006716683
          Length = 884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           C+++D D
Sbjct: 128 CLKIDED 134
>XP_006716682
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/7 (42%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           C+++D D
Sbjct: 170 CLKIDED 176
>XP_005263082
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   CMRVDSD 8
           CM++D D
Sbjct: 854 CMQMDKD 860
>XP_006713749
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 2   CMRVDSD 8
           CM VD D
Sbjct: 983 CMDVDGD 989
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.127    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 614,298
Number of extensions: 1213
Number of successful extensions: 66
Number of sequences better than 10000.0: 66
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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