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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              19     869
NP_001091680                                                           19     869
NP_001091679                                                           19     869
XP_006713048                                                           19     869
XP_006713047                                                           19     869
XP_006713046                                                           19     869
XP_005264943                                                           19     869
NP_002221                                                              17    2528
NP_068831                                                              17    2528
XP_006721941                                                           17    2528
XP_006721940                                                           17    2528
XP_006721939                                                           17    2528
XP_006721938                                                           17    2528
XP_006721937                                                           17    2528
XP_006721936                                                           17    2528
XP_006721935                                                           17    2528
XP_006721934                                                           17    2528
XP_005257370                                                           17    2528
NP_059344                                                              16    5631
NP_006331                                                              16    5631
NP_059345                                                              16    5631
XP_005257005                                                           16    5631
XP_006721701                                                           16    5631
XP_006721700                                                           16    5631
XP_005257002                                                           16    5631
XP_005257001                                                           16    5631
XP_006721699                                                           16    5631
XP_006721698                                                           16    5631
XP_005257000                                                           16    5631
NP_001138360                                                           16    5631
NP_001229825                                                           16    7355
NP_001229826                                                           16    7355
NP_055477                                                              16    7355
NP_001129501                                                           16    7355
XP_006724448                                                           16    7355
XP_006724447                                                           16    7355
XP_005261922                                                           16    7355
XP_005261921                                                           16    7355
XP_005261920                                                           16    7355
XP_005261919                                                           16    7355
NP_001245221                                                           15    9605
NP_036472                                                              15    9605
NP_001129493                                                           15    9605
NP_001245226                                                           15    9605
NP_775114                                                              15    9605
NP_001245223                                                           15    9605
NP_001245225                                                           15    9605
NP_001245224                                                           15    9605
XP_005260470                                                           15    9605

>NP_001895
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 656 AAVLFRMSE 664



>NP_001091680
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 656 AAVLFRMSE 664



>NP_001091679
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 656 AAVLFRMSE 664



>XP_006713048
          Length = 720

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 656 AAVLFRMSE 664



>XP_006713047
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 649 AAVLFRMSE 657



>XP_006713046
          Length = 774

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 649 AAVLFRMSE 657



>XP_005264943
          Length = 781

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF+MSE
Sbjct: 656 AAVLFRMSE 664



>NP_002221
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>NP_068831
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721941
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721940
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721939
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721938
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721937
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721936
          Length = 745

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 646 AAVLFRISE 654



>XP_006721935
          Length = 762

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 663 AAVLFRISE 671



>XP_006721934
          Length = 783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 684 AAVLFRISE 692



>XP_005257370
          Length = 783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAVLFQMSE 9
           AAVLF++SE
Sbjct: 684 AAVLFRISE 692



>NP_059344
          Length = 521

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>NP_006331
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>NP_059345
          Length = 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>XP_005257005
          Length = 522

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>XP_006721701
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 69 VLFQMAE 75



>XP_006721700
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>XP_005257002
          Length = 553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLFQMSE 9
           VLFQM+E
Sbjct: 108 VLFQMAE 114



>XP_005257001
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLFQMSE 9
           VLFQM+E
Sbjct: 108 VLFQMAE 114



>XP_006721699
          Length = 554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLFQMSE 9
           VLFQM+E
Sbjct: 108 VLFQMAE 114



>XP_006721698
          Length = 555

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLFQMSE 9
           VLFQM+E
Sbjct: 108 VLFQMAE 114



>XP_005257000
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLFQMSE 9
           VLFQM+E
Sbjct: 108 VLFQMAE 114



>NP_001138360
          Length = 534

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  VLFQMSE 9
          VLFQM+E
Sbjct: 75 VLFQMAE 81



>NP_001229825
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1395 AAVLFEM 1401



>NP_001229826
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1295 AAVLFEM 1301



>NP_055477
          Length = 1572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1364 AAVLFEM 1370



>NP_001129501
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1386 AAVLFEM 1392



>XP_006724448
          Length = 1490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1282 AAVLFEM 1288



>XP_006724447
          Length = 1516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1308 AAVLFEM 1314



>XP_005261922
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1317 AAVLFEM 1323



>XP_005261921
          Length = 1581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1373 AAVLFEM 1379



>XP_005261920
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1386 AAVLFEM 1392



>XP_005261919
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AAVLFQM 7
            AAVLF+M
Sbjct: 1395 AAVLFEM 1401



>NP_001245221
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 728 AAVLYQRSK 736



>NP_036472
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 748 AAVLYQRSK 756



>NP_001129493
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 728 AAVLYQRSK 736



>NP_001245226
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 529 AAVLYQRSK 537



>NP_775114
          Length = 925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 748 AAVLYQRSK 756



>NP_001245223
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 529 AAVLYQRSK 537



>NP_001245225
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 529 AAVLYQRSK 537



>NP_001245224
          Length = 706

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 529 AAVLYQRSK 537



>XP_005260470
          Length = 924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAVLFQMSE 9
           AAVL+Q S+
Sbjct: 747 AAVLYQRSK 755



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.326    0.125    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 292,240
Number of extensions: 343
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)