Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              17    4312
NP_001008487                                                           17    4312
NP_001008486                                                           17    4312
NP_001008485                                                           17    4312
NP_060306                                                              17    4312
NP_001157947                                                           17    4312
XP_006714104                                                           17    4312
XP_005265800                                                           17    4312
XP_006714103                                                           17    4312
XP_006714102                                                           17    4312
XP_005247622                                                           17    4312
XP_005247621                                                           17    4312
XP_006713744                                                           17    4312
XP_005247620                                                           17    4312
XP_005247619                                                           17    4312
XP_005247618                                                           17    4312
XP_005247617                                                           17    4312
XP_005247616                                                           17    4312
NP_776253                                                              16    7355
NP_003092                                                              16    7355
NP_001239441                                                           16    7355
NP_001239440                                                           16    7355
XP_005245126                                                           16    7355
>NP_006197
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           AA VLVLLV
Sbjct: 528 AAAVLVLLV 536
>NP_001008487
          Length = 461

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 348 SARVLLLLV 356
>NP_001008486
          Length = 471

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 338 SARVLLLLV 346
>NP_001008485
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>NP_060306
          Length = 487

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>NP_001157947
          Length = 370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 257 SARVLLLLV 265
>XP_006714104
          Length = 832

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           AA VLVLLV
Sbjct: 553 AAAVLVLLV 561
>XP_005265800
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           AA VLVLLV
Sbjct: 528 AAAVLVLLV 536
>XP_006714103
          Length = 1111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           AA VLVLLV
Sbjct: 550 AAAVLVLLV 558
>XP_006714102
          Length = 1114

 Score = 16.5 bits (31), Expect =  4312
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           AA VLVLLV
Sbjct: 553 AAAVLVLLV 561
>XP_005247622
          Length = 481

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 348 SARVLLLLV 356
>XP_005247621
          Length = 502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 389 SARVLLLLV 397
>XP_006713744
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>XP_005247620
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>XP_005247619
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>XP_005247618
          Length = 507

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 374 SARVLLLLV 382
>XP_005247617
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 389 SARVLLLLV 397
>XP_005247616
          Length = 522

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AARVLVLLV 9
           +ARVL+LLV
Sbjct: 389 SARVLLLLV 397
>NP_776253
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           +ARVL LLV
Sbjct: 408 SARVLFLLV 416
>NP_003092
          Length = 550

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           +ARVLVL V
Sbjct: 358 SARVLVLCV 366
>NP_001239441
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           +ARVLVL V
Sbjct: 293 SARVLVLCV 301
>NP_001239440
          Length = 492

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           +ARVLVL V
Sbjct: 300 SARVLVLCV 308
>XP_005245126
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AARVLVLLV 9
           +ARVL LLV
Sbjct: 408 SARVLFLLV 416
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.348    0.154    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 229,445
Number of extensions: 226
Number of successful extensions: 23
Number of sequences better than 10000.0: 23
Number of HSP's gapped: 23
Number of HSP's successfully gapped: 23
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package