Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           18    1135
NP_001277143                                                           18    1135
NP_001319                                                              18    1135
NP_001012632                                                           18    1135
NP_001077383                                                           18    1135
NP_001320                                                              18    1135
NP_073713                                                              18    1135
XP_005269629                                                           18    1135
XP_005269628                                                           18    1135
XP_005269627                                                           18    1135
XP_005269626                                                           18    1135
XP_006717706                                                           18    1135
XP_005269625                                                           18    1135
XP_005269624                                                           18    1135
XP_006717705                                                           18    1135
XP_005269622                                                           18    1135
XP_005269621                                                           18    1135
XP_006717704                                                           18    1135
XP_005269619                                                           18    1135
XP_005269618                                                           18    1135
XP_005272320                                                           18    1135
XP_005272319                                                           18    1135
XP_005272318                                                           18    1135
NP_001273568                                                           17    2528
NP_001273569                                                           17    2528
NP_055755                                                              17    2528
NP_001074008                                                           16    7355
XP_006712501                                                           16    7355
NP_000960                                                              15    9605
NP_005106                                                              15    9605
NP_059447                                                              15    9605
NP_954857                                                              15    9605
NP_001277082                                                           15    9605
NP_001277078                                                           15    9605
NP_001277079                                                           15    9605
NP_116101                                                              15    9605
NP_001277081                                                           15    9605
NP_001277084                                                           15    9605
NP_001277080                                                           15    9605
NP_954858                                                              15    9605
NP_001277083                                                           15    9605
NP_598376                                                              15    9605
NP_001162578                                                           15    9605
XP_005262467                                                           15    9605
XP_005262466                                                           15    9605
XP_005262465                                                           15    9605
NP_001094827                                                           15    9605
NP_001162577                                                           15    9605
NP_056077                                                              15    9605
>NP_001277144
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>NP_001277143
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>NP_001319
          Length = 440

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 169 AARIRGETL 177
>NP_001012632
          Length = 429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 158 AARIRGETL 166
>NP_001077383
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>NP_001320
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>NP_073713
          Length = 985

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 715 AARIRGETL 723
>XP_005269629
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269628
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269627
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269626
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_006717706
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269625
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269624
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_006717705
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269622
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269621
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_006717704
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269619
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005269618
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 175 AARIRGETL 183
>XP_005272320
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 158 AARIRGETL 166
>XP_005272319
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 158 AARIRGETL 166
>XP_005272318
          Length = 441

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARIRGE L
Sbjct: 169 AARIRGETL 177
>NP_001273568
          Length = 438

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  AARIRGEML 9
          AA++RGE+L
Sbjct: 74 AAQLRGELL 82
>NP_001273569
          Length = 401

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  AARIRGEML 9
          AA++RGE+L
Sbjct: 37 AAQLRGELL 45
>NP_055755
          Length = 547

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   AARIRGEML 9
           AA++RGE+L
Sbjct: 183 AAQLRGELL 191
>NP_001074008
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           AR+RGE+
Sbjct: 454 ARLRGEL 460
>XP_006712501
          Length = 1080

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           AR+RGE+
Sbjct: 454 ARLRGEL 460
>NP_000960
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  ARIRGEML 9
          ARI G+M+
Sbjct: 67 ARIEGDMI 74
>NP_005106
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AARIRGE 7
           AARI GE
Sbjct: 732 AARIEGE 738
>NP_059447
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AARIRGE 7
           AARI GE
Sbjct: 732 AARIEGE 738
>NP_954857
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277082
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277078
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277079
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_116101
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277081
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277084
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277080
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_954858
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_001277083
          Length = 117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ARIRGEML 9
           ARI GE+L
Sbjct: 108 ARILGELL 115
>NP_598376
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           A ++RGE+L
Sbjct: 559 AHKLRGELL 567
>NP_001162578
          Length = 1245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARI+G+ +
Sbjct: 294 AARIKGDAM 302
>XP_005262467
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>XP_005262466
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>XP_005262465
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           A+IRGE+
Sbjct: 281 AKIRGEL 287
>NP_001094827
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ARIRGEM 8
           A+IRGE+
Sbjct: 272 AKIRGEL 278
>NP_001162577
          Length = 1279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARI+G+ +
Sbjct: 294 AARIKGDAM 302
>NP_056077
          Length = 1320

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AARIRGEML 9
           AARI+G+ +
Sbjct: 294 AARIKGDAM 302
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.332    0.141    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 415,339
Number of extensions: 400
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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