Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              18    1482
NP_055733                                                              15    9605
NP_001275559                                                           15    9605
NP_003743                                                              15    9605
NP_001275558                                                           15    9605
NP_001254503                                                           15    9605
NP_001273407                                                           15    9605
NP_001032897                                                           15    9605
NP_057149                                                              15    9605
NP_001186071                                                           15    9605
NP_001093131                                                           15    9605
NP_004431                                                              15    9605
XP_006726609                                                           15    9605
XP_005255592                                                           15    9605
XP_006720498                                                           15    9605
XP_006719787                                                           15    9605
XP_005248728                                                           15    9605
XP_005248726                                                           15    9605
XP_006710027                                                           15    9605
>NP_004295
          Length = 1620

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AAREILLM 8
           AAREILLM
Sbjct: 371 AAREILLM 378
>NP_055733
          Length = 802

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   REILLMS 9
           REI+LMS
Sbjct: 336 REIVLMS 342
>NP_001275559
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AAREILLM 8
          AA+E+LL+
Sbjct: 29 AAKEVLLL 36
>NP_003743
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001275558
          Length = 993

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AAREILLM 8
          AA+E+LL+
Sbjct: 29 AAKEVLLL 36
>NP_001254503
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001273407
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 575 ARDLMLMS 582
>NP_001032897
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_057149
          Length = 137

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AREILLMS 9
           ARE+LL S
Sbjct: 115 AREVLLAS 122
>NP_001186071
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 585 ARDLMLMS 592
>NP_001093131
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 586 ARDLMLMS 593
>NP_004431
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AAREILLM 8
          AA+E+LL+
Sbjct: 29 AAKEVLLL 36
>XP_006726609
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAREILLMS 9
           A +E+L+MS
Sbjct: 446 AGKELLIMS 454
>XP_005255592
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AREILLMS 9
           AR+++LMS
Sbjct: 586 ARDLMLMS 593
>XP_006720498
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  REILLMS 9
          REI+LMS
Sbjct: 64 REIVLMS 70
>XP_006719787
          Length = 2838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAREILLMS 9
           A +E+L+MS
Sbjct: 446 AGKELLIMS 454
>XP_005248728
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AAREILLM 8
          AA+E+LL+
Sbjct: 29 AAKEVLLL 36
>XP_005248726
          Length = 994

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  AAREILLM 8
          AA+E+LL+
Sbjct: 29 AAKEVLLL 36
>XP_006710027
          Length = 2837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAREILLMS 9
           A +E+L+MS
Sbjct: 446 AGKELLIMS 454
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.133    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 306,571
Number of extensions: 232
Number of successful extensions: 19
Number of sequences better than 10000.0: 19
Number of HSP's gapped: 19
Number of HSP's successfully gapped: 19
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package