Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              19     665
XP_005273257                                                           19     665
NP_005145                                                              17    3301
NP_001122082                                                           17    3301
NP_001269978                                                           17    3301
XP_006720825                                                           17    3301
XP_006720824                                                           17    3301
NP_008949                                                              16    5631
NP_116205                                                              16    5631
NP_060804                                                              16    5631
XP_005259402                                                           16    5631
XP_005259401                                                           16    5631
XP_006717006                                                           16    5631
XP_006717005                                                           16    5631
XP_006717004                                                           16    5631
XP_006717003                                                           16    5631
XP_005251736                                                           16    5631
NP_001093128                                                           16    5631
NP_001093130                                                           16    5631
NP_006411                                                              16    7355
XP_005260309                                                           16    7355
XP_006720470                                                           16    7355
NP_060960                                                              15    9605
NP_001277182                                                           15    9605
NP_570629                                                              15    9605
NP_001034439                                                           15    9605
NP_001927                                                              15    9605
NP_001277181                                                           15    9605
NP_689687                                                              15    9605
NP_065924                                                              15    9605
NP_689811                                                              15    9605
NP_001275708                                                           15    9605
NP_001094345                                                           15    9605
NP_000942                                                              15    9605
NP_001275709                                                           15    9605
XP_006723349                                                           15    9605
XP_005257162                                                           15    9605
XP_005257160                                                           15    9605
XP_005257159                                                           15    9605
XP_005257157                                                           15    9605
XP_005257155                                                           15    9605
XP_005257154                                                           15    9605
XP_005257153                                                           15    9605
XP_005257152                                                           15    9605
XP_006715935                                                           15    9605
XP_006715934                                                           15    9605
XP_005265408                                                           15    9605
>NP_064450
          Length = 1722

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    AEENSLTE 9
            AEENSLTE
Sbjct: 1626 AEENSLTE 1633
>XP_005273257
          Length = 1726

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    AEENSLTE 9
            AEENSLTE
Sbjct: 1630 AEENSLTE 1637
>NP_005145
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           AEEN +TE
Sbjct: 509 AEENEITE 516
>NP_001122082
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           AEEN +TE
Sbjct: 509 AEENEITE 516
>NP_001269978
          Length = 1012

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           AEEN +TE
Sbjct: 432 AEENEITE 439
>XP_006720825
          Length = 1089

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           AEEN +TE
Sbjct: 509 AEENEITE 516
>XP_006720824
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           AEEN +TE
Sbjct: 509 AEENEITE 516
>NP_008949
          Length = 2325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1812 AAEENSKME 1820
>NP_116205
          Length = 783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EENSLTE 9
           E+NSLTE
Sbjct: 555 EKNSLTE 561
>NP_060804
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EENSLTE 9
           EEN LTE
Sbjct: 124 EENKLTE 130
>XP_005259402
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EENSLTE 9
           E+NSLTE
Sbjct: 308 EKNSLTE 314
>XP_005259401
          Length = 759

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   EENSLTE 9
           E+NSLTE
Sbjct: 531 EKNSLTE 537
>XP_006717006
          Length = 1760

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1232 AAEENSKME 1240
>XP_006717005
          Length = 1788

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1260 AAEENSKME 1268
>XP_006717004
          Length = 2240

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1812 AAEENSKME 1820
>XP_006717003
          Length = 2278

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1812 AAEENSKME 1820
>XP_005251736
          Length = 2325

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AAEENSLTE 9
            AAEENS  E
Sbjct: 1812 AAEENSKME 1820
>NP_001093128
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EENSLTE 9
           EEN LTE
Sbjct: 124 EENKLTE 130
>NP_001093130
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   EENSLTE 9
           EEN LTE
Sbjct: 124 EENKLTE 130
>NP_006411
          Length = 1785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAEENSLTE 9
           AAE++ LTE
Sbjct: 304 AAEKHGLTE 312
>XP_005260309
          Length = 1784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AAEENSLTE 9
           AAE++ LTE
Sbjct: 303 AAEKHGLTE 311
>XP_006720470
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AEENSLTE 9
           +EENSL E
Sbjct: 146 SEENSLEE 153
>NP_060960
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EENSLTE 9
           ++NSLTE
Sbjct: 161 DDNSLTE 167
>NP_001277182
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AEENSLTE 9
           AE+NSL++
Sbjct: 120 AEDNSLSQ 127
>NP_570629
          Length = 865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   AEENSLTE 9
           AE+NSL++
Sbjct: 120 AEDNSLSQ 127
>NP_001034439
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AEENSLTE 9
          AE+NSL++
Sbjct: 56 AEDNSLSQ 63
>NP_001927
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AEENSLTE 9
          AE+NSL++
Sbjct: 58 AEDNSLSQ 65
>NP_001277181
          Length = 758

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AEENSLTE 9
          AE+NSL++
Sbjct: 58 AEDNSLSQ 65
>NP_689687
          Length = 215

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   EENSLTE 9
           E+NS+TE
Sbjct: 194 EQNSVTE 200
>NP_065924
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EENSLTE 9
           EEN +TE
Sbjct: 127 EENQITE 133
>NP_689811
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>NP_001275708
          Length = 846

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>NP_001094345
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>NP_000942
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  EENSLTE 9
          E+N+LTE
Sbjct: 82 EDNTLTE 88
>NP_001275709
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_006723349
          Length = 202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  EENSLTE 9
          E+N+LTE
Sbjct: 82 EDNTLTE 88
>XP_005257162
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257160
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257159
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257157
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257155
          Length = 862

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257154
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257153
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_005257152
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1  AAEENSLTE 9
          ++EE++LTE
Sbjct: 72 SSEEDALTE 80
>XP_006715935
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AEENSLTE 9
          AE+NSL++
Sbjct: 59 AEDNSLSQ 66
>XP_006715934
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  AEENSLTE 9
          AE+NSL++
Sbjct: 59 AEDNSLSQ 66
>XP_005265408
          Length = 716

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   EENSLTE 9
           EEN +TE
Sbjct: 127 EENQITE 133
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.274   0.0954    0.206 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 519,814
Number of extensions: 599
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.4 bits)
S2: 28 (15.4 bits)

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