Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001157745                                                           16    5631
NP_001074010                                                           16    5631
NP_001159756                                                           16    5631
NP_006420                                                              16    5631
NP_001009570                                                           16    5631
NP_001159757                                                           16    5631
NP_057153                                                              16    5631
NP_001188408                                                           16    5631
NP_055646                                                              16    5631
XP_005254311                                                           16    5631
XP_006720508                                                           16    5631
XP_006720507                                                           16    5631
XP_005254310                                                           16    5631
XP_005254309                                                           16    5631
XP_005254306                                                           16    5631
XP_005254305                                                           16    5631
XP_005254304                                                           16    5631
XP_005254303                                                           16    5631
XP_006720506                                                           16    5631
XP_005254302                                                           16    5631
XP_005254301                                                           16    5631
XP_006720505                                                           16    5631
XP_005254300                                                           16    5631
XP_006713495                                                           16    5631
NP_000287                                                              16    7355
NP_001009944                                                           16    7355
NP_006651                                                              16    7355
NP_001258791                                                           16    7355
NP_001002796                                                           16    7355
NP_078993                                                              16    7355
NP_653267                                                              16    7355
NP_775787                                                              16    7355
XP_006720958                                                           16    7355
XP_006720957                                                           16    7355
XP_005255427                                                           16    7355
XP_006720956                                                           16    7355
XP_006720955                                                           16    7355
XP_006720954                                                           16    7355
XP_006720953                                                           16    7355
XP_006720952                                                           16    7355
XP_006714757                                                           16    7355
XP_006714756                                                           16    7355
XP_005272148                                                           16    7355
XP_005272147                                                           16    7355
XP_006714755                                                           16    7355
XP_005272146                                                           16    7355
XP_005272145                                                           16    7355
XP_005272144                                                           16    7355
XP_005272143                                                           16    7355
XP_005272142                                                           16    7355
XP_005272141                                                           16    7355
XP_005272140                                                           16    7355
XP_005272139                                                           16    7355
NP_000693                                                              15    9605
NP_001276989                                                           15    9605
NP_004627                                                              15    9605
NP_001276990                                                           15    9605
NP_001005914                                                           15    9605
NP_002787                                                              15    9605
NP_079172                                                              15    9605
NP_001273685                                                           15    9605
NP_001121697                                                           15    9605
NP_689477                                                              15    9605
NP_001074016                                                           15    9605
NP_003111                                                              15    9605
NP_079464                                                              15    9605
NP_037499                                                              15    9605
NP_001252519                                                           15    9605
NP_958831                                                              15    9605
NP_001139107                                                           15    9605
NP_001252518                                                           15    9605
XP_005248216                                                           15    9605
XP_006714024                                                           15    9605
>NP_001157745
          Length = 3065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2222 SDLLGKSG 2229
>NP_001074010
          Length = 2856

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2013 SDLLGKSG 2020
>NP_001159756
          Length = 456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           +ADVLGR
Sbjct: 251 SADVLGR 257
>NP_006420
          Length = 543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           +ADVLGR
Sbjct: 338 SADVLGR 344
>NP_001009570
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           +ADVLGR
Sbjct: 134 SADVLGR 140
>NP_001159757
          Length = 499

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           +ADVLGR
Sbjct: 294 SADVLGR 300
>NP_057153
          Length = 125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AADVLGRSG 9
          AAD  GR+G
Sbjct: 34 AADARGRAG 42
>NP_001188408
          Length = 1048

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           AAD  GR+G
Sbjct: 957 AADARGRAG 965
>NP_055646
          Length = 2925

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AADVLGRSG 9
            AAD+L R G
Sbjct: 1908 AADLLNREG 1916
>XP_005254311
          Length = 1627

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ADVLGRSG 9
           +D+LG+SG
Sbjct: 783 SDLLGKSG 790
>XP_006720508
          Length = 2658

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 1814 SDLLGKSG 1821
>XP_006720507
          Length = 2763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 1919 SDLLGKSG 1926
>XP_005254310
          Length = 2906

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2062 SDLLGKSG 2069
>XP_005254309
          Length = 2956

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2112 SDLLGKSG 2119
>XP_005254306
          Length = 3066

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2222 SDLLGKSG 2229
>XP_005254305
          Length = 3114

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_005254304
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_005254303
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_006720506
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_005254302
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_005254301
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_006720505
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_005254300
          Length = 3115

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    ADVLGRSG 9
            +D+LG+SG
Sbjct: 2271 SDLLGKSG 2278
>XP_006713495
          Length = 2969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    AADVLGRSG 9
            AAD+L R G
Sbjct: 1952 AADLLNREG 1960
>NP_000287
          Length = 4302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2450 VLGRSG 2455
>NP_001009944
          Length = 4303

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2450 VLGRSG 2455
>NP_006651
          Length = 633

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           AAD+  RSG
Sbjct: 456 AADLANRSG 464
>NP_001258791
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADVLGRSG 9
           A +LGRSG
Sbjct: 523 AFILGRSG 530
>NP_001002796
          Length = 778

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 419 AADVTGKS 426
>NP_078993
          Length = 999

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 640 AADVTGKS 647
>NP_653267
          Length = 4753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    DVLGRS 8
            DVLGRS
Sbjct: 1641 DVLGRS 1646
>NP_775787
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ADVLGRSG 9
           A +LGRSG
Sbjct: 512 AFILGRSG 519
>XP_006720958
          Length = 2675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2487 VLGRSG 2492
>XP_006720957
          Length = 2688

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2487 VLGRSG 2492
>XP_005255427
          Length = 3288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 1435 VLGRSG 1440
>XP_006720956
          Length = 3895

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2042 VLGRSG 2047
>XP_006720955
          Length = 4279

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2426 VLGRSG 2431
>XP_006720954
          Length = 4334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2487 VLGRSG 2492
>XP_006720953
          Length = 4339

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2487 VLGRSG 2492
>XP_006720952
          Length = 4340

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    VLGRSG 9
            VLGRSG
Sbjct: 2487 VLGRSG 2492
>XP_006714757
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 202 AADVTGKS 209
>XP_006714756
          Length = 607

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 248 AADVTGKS 255
>XP_005272148
          Length = 692

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 373 AADVTGKS 380
>XP_005272147
          Length = 732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 373 AADVTGKS 380
>XP_006714755
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 375 AADVTGKS 382
>XP_005272146
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 381 AADVTGKS 388
>XP_005272145
          Length = 747

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 388 AADVTGKS 395
>XP_005272144
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 434 AADVTGKS 441
>XP_005272143
          Length = 753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 434 AADVTGKS 441
>XP_005272142
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 434 AADVTGKS 441
>XP_005272141
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 408 AADVTGKS 415
>XP_005272140
          Length = 792

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 434 AADVTGKS 441
>XP_005272139
          Length = 793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AADVLGRS 8
           AADV G+S
Sbjct: 434 AADVTGKS 441
>NP_000693
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  AADVLGRSG 9
          A DVL R G
Sbjct: 66 AQDVLARDG 74
>NP_001276989
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           AAD++GR
Sbjct: 190 AADLMGR 196
>NP_004627
          Length = 749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           AAD++GR
Sbjct: 190 AADLMGR 196
>NP_001276990
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           AAD++GR
Sbjct: 190 AADLMGR 196
>NP_001005914
          Length = 748

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AADVLGR 7
           AAD++GR
Sbjct: 190 AADLMGR 196
>NP_002787
          Length = 264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AADVLGRSG 9
          AAD+LG  G
Sbjct: 68 AADMLGSYG 76
>NP_079172
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   VLGRSG 9
           +LGRSG
Sbjct: 609 ILGRSG 614
>NP_001273685
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ADVLGRS 8
           ADV+G+S
Sbjct: 542 ADVIGKS 548
>NP_001121697
          Length = 371

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AADVLGRSG 9
          A ++LGR+G
Sbjct: 23 ALELLGRAG 31
>NP_689477
          Length = 364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AADVLGRSG 9
          A ++LGR+G
Sbjct: 23 ALELLGRAG 31
>NP_001074016
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           + +VLGR G
Sbjct: 254 SGEVLGRGG 262
>NP_003111
          Length = 270

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           + +VLGR G
Sbjct: 253 SGEVLGRGG 261
>NP_079464
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           A +++GR G
Sbjct: 428 AGEIMGRGG 436
>NP_037499
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ADVLGRS 8
           ADV+G+S
Sbjct: 541 ADVIGKS 547
>NP_001252519
          Length = 920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DVLGRS 8
           D+LGRS
Sbjct: 458 DILGRS 463
>NP_958831
          Length = 1013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DVLGRS 8
           D+LGRS
Sbjct: 551 DILGRS 556
>NP_001139107
          Length = 562

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   AADVLGRSG 9
           A +++GR G
Sbjct: 410 AGEIMGRGG 418
>NP_001252518
          Length = 1032

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DVLGRS 8
           D+LGRS
Sbjct: 570 DILGRS 575
>XP_005248216
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ADVLGRS 8
           ADV+G+S
Sbjct: 174 ADVIGKS 180
>XP_006714024
          Length = 785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ADVLGRS 8
           ADV+G+S
Sbjct: 518 ADVIGKS 524
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.134    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 535,355
Number of extensions: 1102
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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