Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003550                                                              18    1482
NP_005019                                                              18    1482
NP_001139732                                                           18    1482
NP_001139731                                                           18    1482
NP_001139730                                                           18    1482
NP_079055                                                              18    1482
XP_006725428                                                           18    1482
XP_006725427                                                           18    1482
XP_006725426                                                           18    1482
XP_006722195                                                           18    1482
XP_006722194                                                           18    1482
XP_006722193                                                           18    1482
XP_006719667                                                           18    1482
XP_005269209                                                           18    1482
XP_006717513                                                           18    1482
NP_079330                                                              18    1935
NP_001273318                                                           17    3301
NP_001273319                                                           17    3301
NP_899243                                                              16    5631
NP_775822                                                              16    5631
NP_006011                                                              16    5631
NP_079353                                                              16    5631
XP_005268222                                                           16    5631
XP_006720133                                                           16    5631
XP_006717062                                                           16    5631
XP_006717061                                                           16    5631
XP_005251851                                                           16    5631
XP_005251850                                                           16    5631
XP_005270470                                                           16    5631
XP_005270469                                                           16    5631
NP_001127854                                                           16    7355
NP_060895                                                              16    7355
NP_055684                                                              16    7355
NP_005002                                                              16    7355
XP_005254968                                                           16    7355
XP_005254967                                                           16    7355
XP_006720570                                                           16    7355
NP_006113                                                              16    7355
NP_001035199                                                           16    7355
NP_777280                                                              15    9605
NP_008830                                                              15    9605
NP_001073883                                                           15    9605
NP_005797                                                              15    9605
NP_003110                                                              15    9605
NP_001245313                                                           15    9605
NP_115921                                                              15    9605
NP_803879                                                              15    9605
NP_803881                                                              15    9605
NP_001258992                                                           15    9605
NP_110428                                                              15    9605
NP_001229291                                                           15    9605
NP_001258991                                                           15    9605
NP_001092270                                                           15    9605
NP_001258990                                                           15    9605
XP_006724671                                                           15    9605
XP_006724670                                                           15    9605
XP_005260965                                                           15    9605
XP_005260773                                                           15    9605
XP_006721327                                                           15    9605
XP_005267749                                                           15    9605
XP_005267222                                                           15    9605
NP_061910                                                              15    9605
>NP_003550
          Length = 416

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 380 AAHAAKTV 387
>NP_005019
          Length = 406

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 370 AAHAAKTV 377
>NP_001139732
          Length = 373

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 337 AAHAAKTV 344
>NP_001139731
          Length = 403

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 367 AAHAAKTV 374
>NP_001139730
          Length = 421

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 385 AAHAAKTV 392
>NP_079055
          Length = 421

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 385 AAHAAKTV 392
>XP_006725428
          Length = 257

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 221 AAHAAKTV 228
>XP_006725427
          Length = 352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 316 AAHAAKTV 323
>XP_006725426
          Length = 352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 316 AAHAAKTV 323
>XP_006722195
          Length = 257

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 221 AAHAAKTV 228
>XP_006722194
          Length = 352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 316 AAHAAKTV 323
>XP_006722193
          Length = 352

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 316 AAHAAKTV 323
>XP_006719667
          Length = 251

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 215 AAHAAKTV 222
>XP_005269209
          Length = 408

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 372 AAHAAKTV 379
>XP_006717513
          Length = 355

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   AAHAARTV 9
           AAHAA+TV
Sbjct: 319 AAHAAKTV 326
>NP_079330
          Length = 1222

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AAAHAARTV 9
           AAAH+A TV
Sbjct: 861 AAAHSAHTV 869
>NP_001273318
          Length = 233

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AAAHAARTV 9
          AAAHA RT+
Sbjct: 85 AAAHAWRTL 93
>NP_001273319
          Length = 211

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AAAHAARTV 9
          AAAHA RT+
Sbjct: 85 AAAHAWRTL 93
>NP_899243
          Length = 1977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    HAARTV 9
            HAARTV
Sbjct: 1744 HAARTV 1749
>NP_775822
          Length = 871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAARTV
Sbjct: 219 HAARTV 224
>NP_006011
          Length = 389

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AAAHAAR 7
          +AAHAAR
Sbjct: 47 SAAHAAR 53
>NP_079353
          Length = 510

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AAAHAART 8
          A  HAART
Sbjct: 87 AVCHAART 94
>XP_005268222
          Length = 184

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AAAHAAR 7
          +AAHAAR
Sbjct: 47 SAAHAAR 53
>XP_006720133
          Length = 1969

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    HAARTV 9
            HAARTV
Sbjct: 1736 HAARTV 1741
>XP_006717062
          Length = 828

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAARTV
Sbjct: 161 HAARTV 166
>XP_006717061
          Length = 872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAARTV
Sbjct: 219 HAARTV 224
>XP_005251851
          Length = 885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAARTV
Sbjct: 219 HAARTV 224
>XP_005251850
          Length = 886

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAARTV
Sbjct: 219 HAARTV 224
>XP_005270470
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AAAHAART 8
          A  HAART
Sbjct: 41 AVCHAART 48
>XP_005270469
          Length = 516

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   AAAHAART 8
           A  HAART
Sbjct: 93  AVCHAART 100
>NP_001127854
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAART+
Sbjct: 122 HAARTI 127
>NP_060895
          Length = 479

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AAAHAAR 7
          AAAHAA+
Sbjct: 90 AAAHAAQ 96
>NP_055684
          Length = 963

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   HAARTV 9
           HAART+
Sbjct: 136 HAARTI 141
>NP_005002
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AAAHAARTV 9
           AAAHA  T+
Sbjct: 410 AAAHAVATL 418
>XP_005254968
          Length = 1156

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAAHA R+
Sbjct: 535 AAAHARRS 542
>XP_005254967
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAAHA R+
Sbjct: 535 AAAHARRS 542
>XP_006720570
          Length = 1181

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAAHA R+
Sbjct: 535 AAAHARRS 542
>NP_006113
          Length = 1150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAAHA R+
Sbjct: 535 AAAHARRS 542
>NP_001035199
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AAAHAARTV 9
           AAAHA  T+
Sbjct: 410 AAAHAVATL 418
>NP_777280
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AAAHAA 6
          AAAHAA
Sbjct: 30 AAAHAA 35
>NP_008830
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AAAHAA 6
          AAAHAA
Sbjct: 30 AAAHAA 35
>NP_001073883
          Length = 2028

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    AAAHAART 8
            AAA AART
Sbjct: 1932 AAAPAART 1939
>NP_005797
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AAAHAA 6
           AAAHAA
Sbjct: 207 AAAHAA 212
>NP_003110
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AAAHAAR 7
           AA HAAR
Sbjct: 528 AALHAAR 534
>NP_001245313
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AAAHAA 6
          AAAHAA
Sbjct: 30 AAAHAA 35
>NP_115921
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    AAAHAAR 7
            A AHAAR
Sbjct: 1093 APAHAAR 1099
>NP_803879
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_803881
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_001258992
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_110428
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_001229291
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_001258991
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_001092270
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>NP_001258990
          Length = 757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>XP_006724671
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>XP_006724670
          Length = 741

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 119 AAAAAART 126
>XP_005260965
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   AAAHAA 6
           AAAHAA
Sbjct: 207 AAAHAA 212
>XP_005260773
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  AAAHAA 6
          AAAHAA
Sbjct: 30 AAAHAA 35
>XP_006721327
          Length = 809

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AAAHAAR 7
           AA HAAR
Sbjct: 528 AALHAAR 534
>XP_005267749
          Length = 1055

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAAHAART 8
           AAA AART
Sbjct: 959 AAAPAART 966
>XP_005267222
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    AAAHAAR 7
            A AHAAR
Sbjct: 1018 APAHAAR 1024
>NP_061910
          Length = 245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   AAAHAARTV 9
           AAA AAR V
Sbjct: 216 AAAQAARDV 224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.108    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 461,459
Number of extensions: 589
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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