CancerDR: Cancer Drug Resistance Database

CSIR - Indraprastha Institute of Information Technology, India

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Tertiary structure of target mutants

We predicted tertiary structure of each drug target and their mutants. This page is designed to view structures of wild type targets and their Mutants. It helps user to see 3D view in Jmol against selected Targets in CancerDR. Note: Java should be enabled in your browser for proper functioning of the this module. For more information, please click Help

Example

Structure Quality Statistics of CDK6
Query Sequence Length	Mapped query sequence	Query sequence covered	Identity of aligned region	Ramachandran allowed region	Ramachandran map	PDB File	Template Alignment
327	1-326	99.69%	100.00%	88.2%	CDK6.pdf	CDK6.pdb	CDK6.hhr

3D-Strucutre of CDK6	List of Mutants
	V.A197S V.D246E V.H139Q V.R168H V.S57P V.T88S V.V190I