CancerDR: Cancer Drug Resistance Database

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Mutations in drug targets


This page is allows user to display different types of mutations (like Amino acid, Codon mutation, cDNA) in drug targets. For more information, please click Help

Example

Summary of mutations in CDK6
Mutation TypeList
Amino Acidp.S57P, p.T88S, p.H139Q, p.R168H, p.V190I, p.A197S, p.D246E
cDNAc.169T>C, c.262A>T, c.417C>G, c.503G>A, c.568G>A, c.589G>T, c.738T>A
Codonc.(169-171)TCC>CCC, c.(262-264)ACA>TCA, c.(415-417)CAC>CAG, c.(502-504)CGC>CAC, c.(568-570)GTC>ATC, c.(589-591)GCC>TCC, c.(736-738)GAT>GAA

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Select any one of the Targets
ABL1 ABL2 AKT1 AKT2 AKT3 ALK AR ATM AURKA AURKB
AURKC BCL2 BMX BRAF BTK CASP3 CCR5 CDK1 CDK2 CDK4
CDK6 CDK7 CTNNB1 DHFR EGFR ERBB2 FGFR1 FGFR3 FLT1 FLT3
FNTA GSK3A GSK3B HDAC1 HDAC2 HDAC3 HDAC6 HDAC8 HSP90AA1 HSP90AB1
HSP90AB4P HSP90B1 HSP90B3P IGF1R IKBKE ITK JAK2 KDR KIT MAP2K1
MAP2K2 MAPK11 MAPK12 MAPK13 MAPK14 MAPK7 MAPK8 MCL1 MDM2 MET
MTOR NFKB1 NTRK1 P4HB PAK1 PARP1 PDGFRA PDGFRB PDK1 PIK3CA
PIK3CB PIK3CD PIK3CG PLK1 PLK2 PLK3 PPM1D PRKAA1 PRKCA PRKCB
PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCSH PRKCZ PRKDC PSENEN
PTK2 PTPN11 PTPN6 RAC1 RET ROCK1 ROCK2 RPS6KA1 RPS6KA2 RPS6KA3
RPS6KA4 RPS6KA5 RPS6KA6 RPS6KB2 RXRA RXRB SGK3 SMO SRC SYK
TBK1 TEC TNF TOP1 WEE1 XIAP