It is important to cluster mutants of a drug target to understand similarity among targets obtained from different sources or cell lines. These clusters are based on sequence similarity, generated using ClustalW. This page allows to visualize alignment Tree of wild type sequences of each target with their mutants. It helps user to view the distance of different mutant sequences in the alignment against selected targets in CancerDR. Click RED button to select mutants and blue button for natural variants against corresponding target. Note: Java should be enabled in your browser for proper functioning of the this module. For more information, please click
Example
Click on the button for Tree view of alignment of "CDK6" with its mutants. User Defined Colours, and group consensus and sequence logos are shown below the alignment.