Welcome to Sequence Card of Peptide


Details of SAPdb entry with Sequence FFf
Primary information
SAPdb ID 1179,
PMID19527662
Peptide NameTriPhenylalanine
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueTransmission Electron Microscopy (TEM), Scanning Electron Microscopy (SEM) and FTIR (Fourier Transform Infrared)
SolventChlorinated alcohol
MethodPeptide stock solution prepared in HFP (1,1,1,3,3,3-hexafluoro-2-propanol) at conc 100mg/ml. Peptide stock solution diluted with water to 2mg/ml.
Conc2mg/ml
TemperatureRoom temperature
Year2009
Self assemblyYes
Type of Self assemblyPlate like Nano-structure
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable
Other
NA
None
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O
Primary information
SAPdb ID 1183,
PMID24468750
Peptide NameTriPhenylalanine
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueInsilico method: MARTINI coarse - grained molecular dynamic
SolventWater
MethodSimulation of a system consisting of 600 FFF peptides and 24 442 water beads in a cubic box of 15.5 nm (corresponding to a peptide concentration of 120 mg/ml with the CG molecular dynamics simulations, using the MARTINI V2.1 force field. Ten 900 ns MD runs have been performed using different initial velocities starting from a state in which the peptides were placed randomly in the water box.
Conc120 mg/ml
Temperature37 °C
Incubation Time600- 900 ns (nanoseconds)
Year2014
Self assemblyYes
Type of Self assemblyNanospheres (in seven out of ten trajectories), Nanorods ( in the 3 out of 10 trajectories)
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
Nanosphere, Nanorod
NA
None
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O
Primary information
SAPdb ID 1184,
PMID24468750
Peptide NameTriPhenylalanine
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueInsilico method: MARTINI coarse - grained molecular dynamic
SolventWater
MethodTo examine the effect of concentration on the formation of FFF nanostructures, they performed two independent 4000 ns long MD simulations at a lower peptide concentration of 45 mg /ml. Simulation of a system consisting of 600 FFF peptides and 24 442 water beads in a cubic box of 15.5 nm (corresponding to a peptide concentration of 45mg/ml with the CG molecular dynamics simulations, using the MARTINI V2.1 force field. T
Conc45 mg/ml
Temperature37 °C
Incubation Time1500 ns
Year2014
Self assemblyYes
Type of Self assemblyNanorod
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
Stable for 2 microseconds
Nanorod
NA
None
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O
Primary information
SAPdb ID 1185,
PMID24468750
Peptide NameTriPhenylalanine
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueInsilico method: MARTINI coarse - grained molecular dynamic
SolventWater
MethodTo examine the effect of concentration on the formation of FFF nanostructures, they performed two independent 4000 ns long MD simulations at a lower peptide concentration of 45 mg /ml. Simulation of a system consisting of 600 FFF peptides and 24 442 water beads in a cubic box of 15.5 nm (corresponding to a peptide concentration of 45mg/ml with the CG molecular dynamics simulations, using the MARTINI V2.1 force field. T
Conc45 mg/ml
Temperature37 °C
Incubation Time3500 ns
Year2014
Self assemblyYes
Type of Self assemblyNanosphere
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
Nanosphere
NA
None
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O
Primary information
SAPdb ID 1186,
PMID24468750
Peptide NameTriPhenylalanine
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueInsilico method: MARTINI coarse - grained molecular dynamic
SolventWater
MethodSimulation of a system consisting of 1800 FFF peptides and 24 442 water beads in a cubic box of 15.5 nm (corresponding to a peptide concentration of 80 mg/ml with the CG molecular dynamics simulations, using the MARTINI V2.1 force field. Ten 900 ns MD runs have been performed using different initial velocities starting from a state in which the peptides were placed randomly in the water box.
Conc80 mg/ml
Temperature37 °C
Incubation Time6000 ns
Year2014
Self assemblyYes
Type of Self assemblyNanorods and Nanosphere
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
Nanosphere, Nanorod
NA
None
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C=O
Primary information
SAPdb ID 1763,
PMID30968092
Peptide NameL-Phe-L-Phe-L-Phe
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/Conjuagatetripeptide
Conjugate partnerNone
TechniqueSEM, TG, VCD, and solid-state NMR
SolventHFIP
Conc10 μL
Temperature 4.9-5.2
Temperature230℃
Year2019
Self assemblyYes
Type of Self assemblynanostructures
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanostructure
NA
None
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1764,
PMID30968092
Peptide NameD-Phe-L-Phe-L-Phe
Peptide sequencefFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/Conjuagatetripeptide
Conjugate partnerNone
TechniqueSEM, TG, VCD, and solid-state NMR
SolventHFIP
Conc10 μL
Temperature 4.9-5.2
Temperature229℃
Year2019
Self assemblyYes
Type of Self assemblynanostructures
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanostructure
NA
None
N[C@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1765,
PMID30968092
Peptide NameL-Phe-D-Phe-L-Phe
Peptide sequenceFfF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/Conjuagatetripeptide
Conjugate partnerNone
TechniqueSEM, TG, VCD, and solid-state NMR
SolventHFIP
Conc10 μL
Temperature 4.9-5.2
Temperature238℃
Year2019
Self assemblyYes
Type of Self assemblynanostructures
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanostructure
NA
None
N[C@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1766,
PMID30968092
Peptide NameLPhe-L-Phe-D-Phe
Peptide sequenceFFf
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/Conjuagatetripeptide
Conjugate partnerNone
TechniqueSEM, TG, VCD, and solid-state NMR
SolventHFIP
Conc10 μL
Temperature 4.9-5.2
Temperature251℃
Year2019
Self assemblyYes
Type of Self assemblynanostructures
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanostructure
NA
None
N[C@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1849,
PMID27548765
Peptide NametriPhenylalanine(FFF)
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueScanning Electron Microscopy (SEM)
Solvent1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)
Conc100 mg/mL
Year2016
Self assemblyNA
Type of Self assemblyhollow nanotubes and spherical nanovesicles, and solid nanorods and nanospheres
Tertiary Structure
(Technique)		Not Predicted),
Linear and Cyclic both
NA
NA
Nanotube, Nanosphere
NA
FFF
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1851,
PMID27548765
Peptide NameFFF
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueScanning Electron Microscopy (SEM)
Solvent1,1,1,3,3,3-hexafluoro-2-propanol (HFIP)
Conc100 mg/mL
Year2016
Self assemblyNA
Type of Self assemblynanotoroid
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Other
NA
FFF
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1961,
PMID28703237
Peptide NameFmoc-FFF
Peptide sequenceFFF
N-Terminal ModificationFmoc [or N-(fluorenyl-9-methoxycarbonyl)]
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
TechniqueFTIR
Year2017
Self assemblyYes
Type of Self assemblyNanofibres
Tertiary Structure
(Technique)		Not Predicted),
Linear
NA
NA
Nanofiber
NA
None
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 1974,
PMID28767108
Peptide Nameferrocene-Phenylalanine-Phenylalanine-Phenylalanine (Fc-FFF)
Peptide sequenceFFF
N-Terminal ModificationFerrocene (FC)
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
Techniqueconfocal laser scanning microscopy (CLSM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and atomic force microscope (AFM)
Solventphosphate buffer
Conc50 mM
Temperature7.2
Temperature60 °C
Incubation Time30 s
Year2017
Self assemblyYes
Type of Self assemblyNanovesicles
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanovesicle
632
None
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 2013,
PMID28955776
Peptide NameH-Phe- Phe-Phe-OH (FFF)
Peptide sequenceFFF
N-Terminal ModificationFree
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
Techniqueultraviolet (UV) absorption spectroscopy, fluorescence spectroscopy and circular dichroism (CD) spectroscopy
SolventTris-NaCl EDTA (TNE) buffer
Temperature7.4
Year2017
Self assemblyYes
Type of Self assemblynanostructured aggregates
Tertiary Structure
(Technique)		Not Predicted),
NA
NA
NA
Nanostructure
NA
None
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O
Primary information
SAPdb ID 2017,
PMID28955776
Peptide NameBoc-FFF
Peptide sequenceFFF
N-Terminal ModificationBoc (or t-butoxycarbonyl)
C-Terminal ModificationFree
Non-Terminal ModificationNone
Length3
Peptide/ConjuagatePeptide
Conjugate partnerNone
Techniqueultra- violet (UV) absorption spectroscopy, fluorescence spectroscopy, cir- cular dichroism (CD) study, viscosity measurement and thermal dena- turation analysis of DNA
SolventTris-NaCl EDTA (TNE) buffer
Temperature7.4
Year2017
Self assemblyYes
Type of Self assemblybionanospheres
Tertiary Structure
(Technique)		Not Predicted),
Cyclic
NA
NA
Nanosphere
NA
None
N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)O