Browse result page of PRRDB 2.0
| PRRID | Name of Ligand | Source of ligand | Sequence of Ligand | Length of Ligand | Type of Ligand | Occurence | Role of Ligand | Name of Receptor | Type of Reeptor | Source of the Receptor | Localization | Domain | Sequence of Receptor | Swiss prot ID | Length of receptor | Function of Receptor | Assay used | PMID | Year of publication | Pubchem assay |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PRRID_2246 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2246 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2266 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2266 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2276 | Lipopolysaccharide (LPS) Click for more detail | Vibrio harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Pathogenic infection | FmLC5 | C type Lectin (CTL/CLR) | Fenneropenaeus merguiensis | hemocytes | two similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-binding | NA | NA | NA | NA | qRT-PCR | 28958586 | 2017 | NA |
| PRRID_2276 | Lipopolysaccharide (LPS) Click for more detail | Vibrio harveyi (Bacteria) | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | Pathogenic infection | FmLC5 | C type Lectin (CTL/CLR) | Fenneropenaeus merguiensis | hemocytes | two similar carbohydrate recognition domains (CRDs), each CRD contains a Ca2+ binding site-2 and a QPD motif specific for galactose-binding | NA | NA | NA | NA | qRT-PCR | 28958586 | 2017 | NA |
| PRRID_2277 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2277 | Lipopolysaccharide (LPS) Click for more detail | Bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2278 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2278 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | rPtCTL-2 | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28288910 | 2017 | NA |
| PRRID_2279 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2279 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2280 | Peptidoglycan (PGN) Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Peptidoglycan | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2280 | Peptidoglycan (PGN) Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Peptidoglycan | Natural | elicit innate immune response | rMrLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27818342 | 2017 | NA |
| PRRID_2281 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2281 | Lipopolysaccharide (LPS) Click for more detail | Gram-negative and Gram-positive bacteria | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC | NA | Lipopolysaccharide (LPS) | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2282 | Peptidoglycan (PGN) Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Peptidoglycan | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2282 | Peptidoglycan (PGN) Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Peptidoglycan | Natural | elicit innate immune response | MrCTL | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27620819 | 2017 | NA |
| PRRID_2325 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | SpMBP | C type Lectin (CTL/CLR) | Scylla paramamosain | NA | CRD with a QPD (Gln-Pro-Asp) motif | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2325 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | SpMBP | C type Lectin (CTL/CLR) | Scylla paramamosain | NA | CRD with a QPD (Gln-Pro-Asp) motif | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2326 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | MjLecA | C type Lectin (CTL/CLR) | Marsupenaeus japonicus | NA | Single-CRD C-type lectins containing EPN (Glu- Pro-Asn) motif | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2326 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | MjLecA | C type Lectin (CTL/CLR) | Marsupenaeus japonicus | NA | Single-CRD C-type lectins containing EPN (Glu- Pro-Asn) motif | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2327 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | FcLec1 | C type Lectin (CTL/CLR) | F. chinensis | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2327 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O | NA | NA | Natural | elicit innate immune response | FcLec1 | C type Lectin (CTL/CLR) | F. chinensis | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2328 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | NA | Natural | elicit innate immune response | FcLec3 | C type Lectin (CTL/CLR) | F. chinensis | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2328 | Mannose Click for more detail | Bacteria | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | NA | Natural | elicit innate immune response | FcLec3 | C type Lectin (CTL/CLR) | F. chinensis | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2329 | Mannose and fucose Click for more detail | L. monocytogenes (Bacteria) | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Activation of CLEC5A | CLEC5A | C type Lectin (CTL/CLR) | Human | monocytes, macrophages and neutrophils. | NA | Q14DL9.fasta | Q14DL9 | 165 | secretion of proinflammatory cytokines such as TNF, IL-6, CXCL-8, and IP-10. | Binding assay | 28824166 | 2017 | Pubchem_assay |
| PRRID_2329 | Mannose and fucose Click for more detail | L. monocytogenes (Bacteria) | C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)O | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Activation of CLEC5A | CLEC5A | C type Lectin (CTL/CLR) | Human | monocytes, macrophages and neutrophils. | NA | Q14DL9.fasta | Q14DL9 | 165 | secretion of proinflammatory cytokines such as TNF, IL-6, CXCL-8, and IP-10. | Binding assay | 28824166 | 2017 | Pubchem_assay |
| PRRID_2343 | Microbial DNA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | Bacterial infection | DC-SIGN | C type Lectin (CTL/CLR) | Human | monocytes | NA | NA | NA | NA | NA | NA | 28976999 | 2017 | NA |
| PRRID_2343 | Microbial DNA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | Bacterial infection | DC-SIGN | C type Lectin (CTL/CLR) | Human | monocytes | NA | NA | NA | NA | NA | NA | 28976999 | 2017 | NA |
| PRRID_2345 | mono- and di-acylated derivatives Click for more detail | NA | NA | NA | Agonist | Synthetic | Activation of CLRs. | Mincle | C type Lectin (CTL/CLR) | Human | Plasma membrane | carbohydrate recognition domain (CRD) | Q9ULY5.fasta | Q9ULY5 | 219 | inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways. | Flow cytometry | 28776416 | 2017 | Pubchem_assay |
| PRRID_2345 | mono- and di-acylated derivatives Click for more detail | NA | NA | NA | Agonist | Synthetic | Activation of CLRs. | Mincle | C type Lectin (CTL/CLR) | Human | Plasma membrane | carbohydrate recognition domain (CRD) | Q9ULY5.fasta | Q9ULY5 | 219 | inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways. | Flow cytometry | 28776416 | 2017 | Pubchem_assay |
| PRRID_2419 | NA Click for more detail | Virus | NA | NA | NA | Natural | NA | CLEC4M (L-SIGN) | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin Domain Family 4, Member M | Q9H2X3.fasta | Q9H2X3 | 399 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2419 | NA Click for more detail | Virus | NA | NA | NA | Natural | NA | CLEC4M (L-SIGN) | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin Domain Family 4, Member M | Q9H2X3.fasta | Q9H2X3 | 399 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2426 | NA Click for more detail | NA | NA | NA | NA | Natural | NA | FcLec5 | C type Lectin (CTL/CLR) | F. chinensis | hemolymph and hepatopancreas | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2426 | NA Click for more detail | NA | NA | NA | NA | Natural | NA | FcLec5 | C type Lectin (CTL/CLR) | F. chinensis | hemolymph and hepatopancreas | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2438 | NA Click for more detail | S. cerevisiae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CREP4 | C type Lectin (CTL/CLR) | B. glabRata | NA | NA | NA | NA | NA | NA | transcriptomic data | 29051762 | 2017 | NA |
| PRRID_2438 | NA Click for more detail | S. cerevisiae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CREP4 | C type Lectin (CTL/CLR) | B. glabRata | NA | NA | NA | NA | NA | NA | transcriptomic data | 29051762 | 2017 | NA |
| PRRID_2442 | NA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CTL4 | C type Lectin (CTL/CLR) | Anopheles gambiae | NA | NA | B2FX81.fasta | B2FX81 | 150 | NA | NA | 29051762 | 2017 | Pubchem_assay |
| PRRID_2442 | NA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Pattern-associated molecular patterns (PAMPs) | Natural | elicit innate immune response | CTL4 | C type Lectin (CTL/CLR) | Anopheles gambiae | NA | NA | B2FX81.fasta | B2FX81 | 150 | NA | NA | 29051762 | 2017 | Pubchem_assay |
| PRRID_2443 | NA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | CTLMA2 | C type Lectin (CTL/CLR) | Anopheles gambiae | NA | NA | B2FX57.fasta | B2FX57 | 165 | NA | NA | 29051762 | 2017 | Pubchem_assay |
| PRRID_2443 | NA Click for more detail | E. coli(Bacteria) | MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK | 396 | Damage-associated molecular patterns (DAMPs) | Natural | elicit innate immune response | CTLMA2 | C type Lectin (CTL/CLR) | Anopheles gambiae | NA | NA | B2FX57.fasta | B2FX57 | 165 | NA | NA | 29051762 | 2017 | Pubchem_assay |
| PRRID_2460 | NA Click for more detail | A.hydrophilla(Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Activation of CLR. | CaNTC | C type Lectin (CTL/CLR) | Carassius auratus | liver, spleen and head-kidney | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2460 | NA Click for more detail | A.hydrophilla(Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Activation of CLR. | CaNTC | C type Lectin (CTL/CLR) | Carassius auratus | liver, spleen and head-kidney | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2468 | NA Click for more detail | F. solani (fungi) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Upregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism. | Dectin-1 | C type Lectin (CTL/CLR) | Human | Human corneal epithelial cells (HCECs) | NA | Q9BXN2.fasta | Q9BXN2 | 247 | decreased AMP mRNA upregulation | RT-PCR, antifungal assay | 28460048 | 2017 | Pubchem_assay |
| PRRID_2468 | NA Click for more detail | F. solani (fungi) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Upregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism. | Dectin-1 | C type Lectin (CTL/CLR) | Human | Human corneal epithelial cells (HCECs) | NA | Q9BXN2.fasta | Q9BXN2 | 247 | decreased AMP mRNA upregulation | RT-PCR, antifungal assay | 28460048 | 2017 | Pubchem_assay |
| PRRID_2470 | NA Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Immunostimulant | rMjGCTL | C type Lectin (CTL/CLR) | Marsupenaeus japonicus | Hemocytes | CRD with a QAP motif. | NA | NA | NA | acts as an opsonin by bind- ing directly to hemocytes to activate their adhesive state for their encapsulation. | Bacterial agglutination assay | 28374848 | 2017 | NA |
| PRRID_2470 | NA Click for more detail | Gram-negative and Gram-positive bacteria | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Immunostimulant | rMjGCTL | C type Lectin (CTL/CLR) | Marsupenaeus japonicus | Hemocytes | CRD with a QAP motif. | NA | NA | NA | acts as an opsonin by bind- ing directly to hemocytes to activate their adhesive state for their encapsulation. | Bacterial agglutination assay | 28374848 | 2017 | NA |
| PRRID_2494 | NA Click for more detail | S. pneumoniae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Immunostimulant | collectin kidney 1 (CL-K1) | C type Lectin (CTL/CLR) | Mice | NA | NA | Q3SXB8.fasta | Q3SXB8 | 272 | binds to microbes and activates the lectin complement pathway | NA | 28068663 | 2017 | Pubchem_assay |
| PRRID_2494 | NA Click for more detail | S. pneumoniae (Bacteria) | NA | NA | Pattern-associated molecular patterns (PAMPs) | Natural | Immunostimulant | collectin kidney 1 (CL-K1) | C type Lectin (CTL/CLR) | Mice | NA | NA | Q3SXB8.fasta | Q3SXB8 | 272 | binds to microbes and activates the lectin complement pathway | NA | 28068663 | 2017 | Pubchem_assay |
| PRRID_2539 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | AmphiCTL1 | C type Lectin (CTL/CLR) | B. belcheri | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2539 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | elicit innate immune response | AmphiCTL1 | C type Lectin (CTL/CLR) | B. belcheri | NA | NA | NA | NA | NA | NA | NA | 29055189 | 2017 | NA |
| PRRID_2541 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2541 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | innate immunity elicitor | rPtCTL-2 | C type Lectin (CTL/CLR) | Portunus trituberculatus | NA | Carbohydrate recognition Domain | NA | NA | NA | recognize nonself invaders and also work as an opsonin to eliminate invaders | PAMPs binding assay | 28916358 | 2017 | NA |
| PRRID_2544 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2544 | Peptidoglycan (PGN) Click for more detail | Bacteria | CC(C(=O)O)OC1C(C(OC(C1O)CO)O)N | NA | Peptidoglycan | Natural | Activation of CLRs. | rCaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2566 | polyinosinic-polycytidylic acid [poly(I:C)] Click for more detail | NA | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Activation of CLRs. | CaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2566 | polyinosinic-polycytidylic acid [poly(I:C)] Click for more detail | NA | C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O | NA | Nucleic Acid | Synthetic | Activation of CLRs. | CaNTC | C type Lectin (CTL/CLR) | Carassius auratus | Liver | Carbohydrate recognition domain (CRD) | NA | NA | NA | pathogen recognition in Qihe 538 crucian carp | Microbial binding assay | 28602683 | 2017 | NA |
| PRRID_2571 | Polyman26 Click for more detail | NA | NA | NA | Agonist | Synthetic | Activation of CLRs. | Dectin-2 | C type Lectin (CTL/CLR) | Human | Plasma membrane | carbohydrate recognition domain (CRD) | Q6EIG7.fasta | Q6EIG7 | 209 | inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways. | Flow cytometry | 28776416 | 2017 | Pubchem_assay |
| PRRID_2571 | Polyman26 Click for more detail | NA | NA | NA | Agonist | Synthetic | Activation of CLRs. | Dectin-2 | C type Lectin (CTL/CLR) | Human | Plasma membrane | carbohydrate recognition domain (CRD) | Q6EIG7.fasta | Q6EIG7 | 209 | inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways. | Flow cytometry | 28776416 | 2017 | Pubchem_assay |
| PRRID_2612 | SAP130 Click for more detail | dead or dying cells(others) | NA | NA | NA | Natural | NA | CLEC4E | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin domain family 4, member E | Q9ULY5.fasta | Q9ULY5 | 219 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2612 | SAP130 Click for more detail | dead or dying cells(others) | NA | NA | NA | Natural | NA | CLEC4E | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin domain family 4, member E | Q9ULY5.fasta | Q9ULY5 | 219 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2633 | spliceosome- associated protein 130 Click for more detail | NA | NA | NA | Protein | Natural | elicit innate immune response | Mincle | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2633 | spliceosome- associated protein 130 Click for more detail | NA | NA | NA | Protein | Natural | elicit innate immune response | Mincle | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 28801521 | 2017 | NA |
| PRRID_2636 | Staphylococcus aureus Click for more detail | Gram-positive bacteria | NA | NA | Protein | Natural | elicit innate immune response | PmCLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27876622 | 2017 | NA |
| PRRID_2636 | Staphylococcus aureus Click for more detail | Gram-positive bacteria | NA | NA | Protein | Natural | elicit innate immune response | PmCLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27876622 | 2017 | NA |
| PRRID_2639 | S. Hemolyticus Click for more detail | Gram-positive bacteria | NA | NA | Protein | Natural | elicit innate immune response | PmCLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27876622 | 2017 | NA |
| PRRID_2639 | S. Hemolyticus Click for more detail | Gram-positive bacteria | NA | NA | Protein | Natural | elicit innate immune response | PmCLec | C type Lectin (CTL/CLR) | NA | NA | NA | NA | NA | NA | NA | NA | 27876622 | 2017 | NA |
| PRRID_2657 | trehalose 6,6′-dimycolate Click for more detail | Mycobacteria (Bacteria) | CCCCCCCCCCCCCCCCCCCCCCCCCC(C(CCCCCCCCCCC1CC1CCCCCCCCCCCCCCCCCC)C(=O)OCC2C(C(C(C(O2)OC3C(C(C(C(O3)COC(=O)C(CCCCCCCCCCC4CC4CCCCCCCCCCCCCCCCCC)C(CCCCCCCCCCCCCCCCCCCCCCCCC)O)O)O)O)O)O)O)O | NA | Glycolipid | Natural | NA | CLEC4E | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin domain family 4, member E | Q9ULY5.fasta | Q9ULY5 | 219 | NA | NA | 29066255 | 2017 | Pubchem_assay |
| PRRID_2657 | trehalose 6,6′-dimycolate Click for more detail | Mycobacteria (Bacteria) | CCCCCCCCCCCCCCCCCCCCCCCCCC(C(CCCCCCCCCCC1CC1CCCCCCCCCCCCCCCCCC)C(=O)OCC2C(C(C(C(O2)OC3C(C(C(C(O3)COC(=O)C(CCCCCCCCCCC4CC4CCCCCCCCCCCCCCCCCC)C(CCCCCCCCCCCCCCCCCCCCCCCCC)O)O)O)O)O)O)O)O | NA | Glycolipid | Natural | NA | CLEC4E | C type Lectin (CTL/CLR) | Human | NA | C-Type Lectin domain family 4, member E | Q9ULY5.fasta | Q9ULY5 | 219 | NA | NA | 29066255 | 2017 | Pubchem_assay |