Detailed description page of PRRDB2.0

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PRRID_2468 details
Primary information
PRRIDPRRID_2468
Ligand NameNA
SourceF. solani (fungi)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandUpregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism.
Name of receptorDectin-1
Type of receptorC type Lectin (CTL/CLR)
Source Human
LocalizationHuman corneal epithelial cells (HCECs)
DomainNA
Sequence of ReceptorQ9BXN2.fasta
Swiss prot IDQ9BXN2
Length Of Receptor247
Functiondecreased AMP mRNA upregulation
Assay usedRT-PCR, antifungal assay
PMID28460048
Year of Publication2017
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_2468
Ligand NameNA
SourceF. solani (fungi)
Sequence of ligandNA
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandUpregulate AMPs hBD2 and LL37 at the mRNA and protein level via a TLR2- and Dectin-1– mediated mechanism.
Name of receptorDectin-1
Type of receptorC type Lectin (CTL/CLR)
Source Human
LocalizationHuman corneal epithelial cells (HCECs)
DomainNA
Sequence of ReceptorQ9BXN2.fasta
Swiss prot IDQ9BXN2
Length Of Receptor247
Functiondecreased AMP mRNA upregulation
Assay usedRT-PCR, antifungal assay
PMID28460048
Year of Publication2017
Pubchem assayPubchem_assay