Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1182	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	90% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1183	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	60% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1184	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1185	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1186	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.01 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	70% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1187	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (0.1 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1188	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (10 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1189	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (1000 micromolar)	No	ATCC	Human glioblastoma cell line	U-87 MG	5.0E+3 cells per well	NA	MTT assay	1 MOI	100% cell death	No	No	NA	No response	NA	NA	NA	NA	17557108
OV_1190	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with RAD001 drug (5mg/kg for 5 days)	No	ATCC	Human glioblastoma cell line	U-87 MG	NA	NA	NA	NA	NA	Athymic nude mice xenograft for U87MG cells	1.0E+7 pfu	NA	Complete reduction of tumor after 90 days in 20-40% of animals	NA	NA	NA	NA	17557108
OV_1191	Adenovirus	ICOVIR-5	DNA	Adenoviridae	None	No	ICOVIR-5 in combination with Temozolomide drug (7.5mg/kg for 5 days)	No	ATCC	Human glioblastoma cell line	U-87 MG	NA	NA	NA	NA	NA	Athymic nude mice xenograft for U87MG cells	1.0E+7 pfu	NA	Complete reduction of tumor after 90 days in 20-40% of animals	NA	NA	NA	NA	17557108
OV_1192	Adenovirus	ONYX-015	DNA	Adenoviridae	None	Yes	No	No	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	95% cancer cell survival	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1193	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	90% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1194	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	ONYX-015 in combination with cisplatin (1microgram/ml)	No	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	50% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1195	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	60% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1196	Adenovirus	ONYX-015	DNA	Adenoviridae	None	No	ONYX-015 in combination with 5 FU (5 microgram/ml)	No	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	60% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1197	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	65% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1198	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	No cell killing at after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1199	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	10% cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1200	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	25% cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1201	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	40% cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1202	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	10% cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1203	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	30% cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1204	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	50% cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1205	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	50% cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1206	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	No cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1207	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	10% cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1208	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	30% cell killing aftewr day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1209	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	40% cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1210	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	20% cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1211	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	30% cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1212	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	60% cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1213	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	Huh-7	NA	NA	MTT assay	1 MOI	60% cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1214	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	10% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1215	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1216	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1217	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1218	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	10% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1219	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1220	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1221	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1222	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	7% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1223	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	17% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1224	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1225	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1226	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	7% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1227	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1228	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1229	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	BEL-7407	NA	NA	MTT assay	1 MOI	50% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1230	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1231	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1232	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1233	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	65% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1234	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1235	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	30% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1236	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	65% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1237	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with cisplatin (1microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	70% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1238	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1239	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1240	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	55% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1241	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	Yes	No	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1242	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 1	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1243	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	20% cancer cell killing after day 2	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1244	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	55% cancer cell killing after day 3	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1245	Adenovirus	ZD55-smac	DNA	Adenoviridae	Deletion of E1B-55K gene and addition of smac gene	No	ZD55-smac in combination with 5 FU (5 microgram/ml)	Virus expressing smac gene	Shanghai cell collection	Liver cancer cell line	SMMC7721	NA	NA	MTT assay	1 MOI	60% cancer cell killing after day 4	No	No	NA	No response	NA	NA	NA	NA	18031615
OV_1260	Adenovirus	AxdAdb-3	DNA	Adenoviridae	Double mutated for E1A and E1B gene	Yes	No	No	ATCC	Prostate cancer cell line	Du145	3.0E+3 cells per well		MTT assay	30 MOI	Surviving cell number reached to 1000	No	No	NA	No response	NA	NA	NA	NA	18063085
OV_1261	Adenovirus	AxdAdb-3	DNA	Adenoviridae	Double mutated for E1A and E1B gene	Yes	No	No	ATCC	Prostate cancer cell line	PC-3	3.0E+3 cells per well		MTT assay	30 MOI	Surviving cell number reached to 10000	No	No	NA	No response	NA	NA	NA	NA	18063085
OV_1262	Adenovirus	AxdAdb-3	DNA	Adenoviridae	Double mutated for E1A and E1B gene	Yes	No	No	ATCC	Prostate cancer cell line	LNCaP	3.0E+3 cells per well		MTT assay	30 MOI	Surviving cell number reached to 1000	No	No	NA	No response	NA	NA	NA	NA	18063085
OV_1263	Adenovirus	AxdAdb-3	DNA	Adenoviridae	Double mutated for E1A and E1B gene	No	No	No	NA	NA	NA	NA	NA	NA	NA	NA	CB-17/Icr-SCID mice orthotopic for DU145 cell line	1.0E+6 pfu per kg	NA	Tumor weight goes down to 100mm after 4 weeks	Intratumorally	NA	NA	NA	18063085
OV_1278	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	98% cell viablity after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1279	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	90% cell viablity after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1280	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	70% cell viabilty after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1281	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	20% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1282	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	100% cell viability after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1283	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	70 % cell viability after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1284	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	20% cell viability after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1285	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	20% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1286	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	80% cell viability after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1287	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	50% cell viability after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1288	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	20% cell viability after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1289	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	LNCaP	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	20% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1290	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	98% cell viability after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1291	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	90% cell viability after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1292	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	100% cell viability after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1293	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	98% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1294	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	98% cell viability after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1295	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	80% cell viability after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1296	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	70% cell viability after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1297	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	60% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1298	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	60% cell viability after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1299	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	40% cell viability after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1300	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	30% cell viability afterd ay 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1301	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PC-3	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	20% cell viability after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1302	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	No significant effect on cell death after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1303	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	No significant effect on cell death after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1304	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	No significant effect on cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1305	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	0.1 MOI	No significant effect on cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1306	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	No significant effect on cell death after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1307	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	No significant effect on cell death after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1308	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	No significant effect on cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1309	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	1 MOI	No significant effect on cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558

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