| Primary information |
|---|
| OV_ID | OV_1263 |
| Virus Name | Adenovirus |
| Strain | AxdAdb-3 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | Double mutated for E1A and E1B gene |
| Virus alone | No |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NA |
| Origin of cell line | NA |
| Cell line | NA |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | NA |
| In-vitro virus concentration | NA |
| In-vitro result | NA |
| Model organism | CB-17/Icr-SCID mice orthotopic for DU145 cell line |
| In-vivo virus concentration | 1 × 10ⶠpfu/kg |
| In-vivo toxicity | NA |
| In-vivo result | Tumor weight goes down to 100mm after 4 weeks |
| Mode of delivery | Intratumorally |
| Pathway induction | NA |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 18063085 |