Detailed description page of Selected OV_ID


OV_1263 details
Primary information
OV_IDOV_1263
Virus Name Adenovirus
StrainAxdAdb-3
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDouble mutated for E1A and E1B gene
Virus aloneNo
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismCB-17/Icr-SCID mice orthotopic for DU145 cell line
In-vivo virus concentration1 × 10⁶ pfu/kg
In-vivo toxicityNA
In-vivo resultTumor weight goes down to 100mm after 4 weeks
Mode of deliveryIntratumorally
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID18063085