Detailed description page of Selected OV_ID


OV_1221 details
Primary information
OV_IDOV_1221
Virus Name Adenovirus
StrainZD55-smac
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1B-55K gene and addition of smac gene
Virus aloneNo
Virus in combination iwth drug/radiationZD55-smac in combination with cisplatin (1microgram/ml)
Immune gene induction in virus genomeVirus expressing smac gene
Source of cell lineShanghai cell collection
Origin of cell lineLiver cancer cell line
Cell lineBEL-7407
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result50% cancer cell killing after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID18031615