Detailed description page of Selected OV_ID


OV_1222 details
Primary information
OV_IDOV_1222
Virus Name Adenovirus
StrainZD55-smac
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1B-55K gene and addition of smac gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing smac gene
Source of cell lineShanghai cell collection
Origin of cell lineLiver cancer cell line
Cell lineBEL-7407
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro result7% cancer cell killing after day 1
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID18031615