Detailed description page of Selected OV_ID


OV_1191 details
Primary information
OV_IDOV_1191
Virus Name Adenovirus
StrainICOVIR-5
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeNone
Virus aloneNo
Virus in combination iwth drug/radiationICOVIR-5 in combination with Temozolomide drug (7.5mg/kg for 5 days)
Immune gene induction in virus genomeNo
Source of cell lineATCC
Origin of cell lineHuman glioblastoma cell line
Cell lineU-87 MG
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismAthymic nude mice xenograft for U87MG cells
In-vivo virus concentration10⁷ pfu
In-vivo toxicityNA
In-vivo resultComplete reduction of tumor after 90 days in 20-40% of animals
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID17557108