Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 100. Click on ID to see further detail.
IDOV_3764 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3765 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3766 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result30% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3767 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3768 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (1 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3769 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3770 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (5 micromolar) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineBxPC-3 | Concentration of cell line5.0E+3 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.5 MOI | In-vitro result30% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3771 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW1990 | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume after 56 days | Mode of deliveryIntratumoral | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3772 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990 | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW1990 | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume to below 500mm after 56 days | Mode of deliveryIntratumoral | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3773 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990/Gemcitabine resistant | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW1990 | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume after 56 days | Mode of deliveryIntratumoral | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_3774 | Virus nameVaccinia virus | Virus strainvv-smac | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of smac and gpt gene in TK | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with gemcitabine (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineType culture collection of china | Origin of cell lineHuman pancreatic cancer cell line | Cell lineSW1990/Gemcitabine resistant | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismBalb/c nude mice xenograft for SW1990 | In-vivo virus concentration2.0E+7 pfu | In-vivo toxicityNA | In-vivo resultSignificant reduction in tumor volume to below 300mm after 56 days | Mode of deliveryIntratumoral | Pathway inducedVirus induce apoptosis in cancer cell | Immunogenic effectNA | Clinical trialNA | PMID30365143 |
IDOV_4084 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4085 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4086 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4087 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4088 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4089 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4090 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4091 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4092 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result25% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4093 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4094 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4095 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result40% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4096 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result95% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4097 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result95% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4098 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result95% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4099 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result95% cell survival after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4100 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4101 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result30% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4102 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4103 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell survival after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4104 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary carcinoma cell line | Cell lineMTH52c | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result20% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4105 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman mammary adenoma cell line | Cell lineZMTH3 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result25% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4106 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of veterinary medicine, germany | Origin of cell lineHuman prostate carcinoma cell line | Cell lineCT1258 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result10% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4107 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineHuman canine soft tissue sarcoma | Cell lineSTSA-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell survival after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4108 | Virus nameVaccinia virus | Virus strainVVstrain LIVP 6.1.1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant for J2R gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1000 mm compared to control 2500mm after 42 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4109 | Virus nameVaccinia virus | Virus strainVVstrain GLV-5b451 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDerived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of colorado, USA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 200 mm compared to control 2500mm after 49 days | Mode of deliveryIntravenous | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID26205404 |
IDOV_4721 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4722 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4723 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4724 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4725 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result25% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4726 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4727 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4728 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4729 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result75% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4730 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result65% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4731 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4732 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4733 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4734 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4735 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4763 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result90% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4764 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result90% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4765 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result75% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4766 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result65% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4767 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4768 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4769 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result75% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4770 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result75% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4771 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4772 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration0.1 MOI | In-vitro result75% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4773 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration1 MOI | In-vitro result50% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4774 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result25% cell survival | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4788 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4791 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4794 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result50% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4797 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4800 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result2% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4803 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4806 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4809 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4812 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4815 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result2% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4818 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result90% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4821 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4824 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result10% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4827 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result10% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4830 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line5000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result1% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4833 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4836 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result80% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4839 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4842 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result50% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4845 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineHEYA8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4848 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4851 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4854 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result90% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4857 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result70% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4860 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineSKOV3 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4863 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result100% cell viability after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4866 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result60% cell viability after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4869 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result40% cell viability after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4872 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result30% cell viability after 4 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4875 | Virus nameVaccinia virus | Virus strainvvDD | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeletion of TK gene and vaccinia growth factor | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman ovarian cancer cell line | Cell lineOVCAR8 | Concentration of cell line50000 cells per well | In-vitro toxicityNA | AssayCell titer Glo luminiscent assay | In-vitro virus concentration10 MOI | In-vitro result25% cell viability after 5 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27119108 |
IDOV_4947 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4948 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result30% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4949 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4950 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineH-1299 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result70% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4951 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result20% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |
IDOV_4952 | Virus nameVaccinia virus | Virus strainvv-IL-24 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of IL-24 gene in tk locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeVirus expressing IL-24 gene | Source of cell lineShanghai cell collection | Origin of cell lineHuman lung cancer cell line | Cell lineA549 | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 MOI | In-vitro result25% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMID27208781 |