Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_3764	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3765	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3766	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	30% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3767	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	BxPC-3	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3768	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (1 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	BxPC-3	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	50% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3769	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	BxPC-3	5.0E+3 cells per well	NA	MTT assay	0.1 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3770	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (5 micromolar)	No	Type culture collection of china	Human pancreatic cancer cell line	BxPC-3	5.0E+3 cells per well	NA	MTT assay	0.5 MOI	30% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3771	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3772	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 500mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3773	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	Yes	No	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_3774	Vaccinia virus	vv-smac	DNA	Poxviridae	Insertion of smac and gpt gene in TK	No	Virus in combination with gemcitabine (50mg/kg)	No	Type culture collection of china	Human pancreatic cancer cell line	SW1990/Gemcitabine resistant	NA	NA	NA	NA	NA	Balb/c nude mice xenograft for SW1990	2.0E+7 pfu	NA	Significant reduction in tumor volume to below 300mm after 56 days	Intratumoral	Virus induce apoptosis in cancer cell	NA	NA	30365143
OV_4084	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4085	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4086	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4087	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4088	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	50% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4089	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4090	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	40% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4091	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	60% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4092	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	25% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4093	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	10% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4094	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	10% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4095	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	40% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4096	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	95% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4097	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	95% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4098	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	95% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4099	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	95% cell survival after 24 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4100	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	60% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4101	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	30% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4102	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	50% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4103	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	60% cell survival after 48 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4104	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary carcinoma cell line	MTH52c	NA	NA	MTT assay	0.1 MOI	20% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4105	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human mammary adenoma cell line	ZMTH3	NA	NA	MTT assay	0.1 MOI	25% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4106	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of veterinary medicine, germany	Human prostate carcinoma cell line	CT1258	NA	NA	MTT assay	0.1 MOI	10% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4107	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of colorado, USA	Human canine soft tissue sarcoma	STSA-1	NA	NA	MTT assay	0.1 MOI	50% cell survival after 72 hours	No	No	NA	No response	NA	NA	NA	NA	26205404
OV_4108	Vaccinia virus	VVstrain LIVP 6.1.1	DNA	Poxviridae	Mutant for J2R gene	Yes	No	No	University of colorado, USA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 1000 mm compared to control 2500mm after 42 days	Intravenous	NA	NA	NA	26205404
OV_4109	Vaccinia virus	VVstrain GLV-5b451	DNA	Poxviridae	Derived from LIVP6.1.1 by inserting glaf-2 gene into J2R locus	Yes	No	No	University of colorado, USA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for STSA-1 cell line (1.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 200 mm compared to control 2500mm after 49 days	Intravenous	NA	NA	NA	26205404
OV_4721	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4722	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4723	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4724	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	50% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4725	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	25% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4726	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4727	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4728	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4729	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4730	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	65% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4731	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.001 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4732	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4733	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4734	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	40% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4735	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4763	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	90% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4764	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	90% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4765	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4766	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	65% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4767	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4768	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4769	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4770	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4771	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4772	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	0.1 MOI	75% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4773	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	1 MOI	50% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4774	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	25% cell survival	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4788	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4791	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4794	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4797	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4800	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	2% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4803	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4806	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4809	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4812	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4815	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	2% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4818	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	90% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4821	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	40% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4824	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	10% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4827	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	10% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4830	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	5000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	1% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4833	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4836	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4839	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4842	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	50% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4845	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	HEYA8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	20% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4848	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4851	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4854	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	90% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4857	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	70% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4860	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	SKOV3	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4863	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	100% cell viability after 24 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4866	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	60% cell viability after 48 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4869	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	40% cell viability after 72 hours	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4872	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	30% cell viability after 4 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4875	Vaccinia virus	vvDD	DNA	Poxviridae	Deletion of TK gene and vaccinia growth factor	Yes	No	No	NA	Human ovarian cancer cell line	OVCAR8	50000 cells per well	NA	Cell titer Glo luminiscent assay	10 MOI	25% cell viability after 5 days	No	No	NA	No response	NA	NA	NA	NA	27119108
OV_4947	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	10 MOI	20% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4948	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	1 MOI	30% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4949	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	0.1 MOI	50% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4950	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	H-1299	NA	NA	MTT assay	0.01 MOI	70% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4951	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	10 MOI	20% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781
OV_4952	Vaccinia virus	vv-IL-24	DNA	Poxviridae	Insertion of IL-24 gene in tk locus	Yes	No	Virus expressing IL-24 gene	Shanghai cell collection	Human lung cancer cell line	A549	NA	NA	MTT assay	1 MOI	25% cell viability	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	27208781

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