Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_4165Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4166Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI20% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4167Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI15% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4168Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI2% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4169Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMCF-75000 cells per wellNAMTT assay1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4170Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4171Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI90% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4172Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI70% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4173Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI40% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4174Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI30% cell viability after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4175Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4176Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI50% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4177Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI20% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4178Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI10% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4179Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinYesNoNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI10% cell viability after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4180Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4181Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI80% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4182Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI58% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4183Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI20% cell viability after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4184Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 2 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay0.1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4185Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI100% cell viability after 24 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4186Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI50% cell viability after 48 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4187Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI10% cell viability after 72 hoursNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4188Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI100% cell killing after 6 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4189Measles virusMV-s-NAPRNAParamyxoviridaeGenetically engineered for expressing H.pylori neutophil activating proteinNoVirus in combination with Alisertib (70nM) before 48 hours of MV infectionNoATCCHuman breast cancer cell lineMDA 231-lu-PA5000 cells per wellNAMTT assay1 MOI100% cell killing after 7 daysNoNoNA No responseNAVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4190Measles virusMV-lambda-NAPRNAParamyxoviridaeGenetically engineered for expressing human lambda immunoglobulin chainYesNoNoNANANANANANANANAFemale athymic nude mice xenograft for MDA-231-lu-P4 (1.0E+6 cells)2.0E+6 TCID50NA All mice dead after 100 daysIntravenousVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4191Measles virusMV-lambda-NAPRNAParamyxoviridaeGenetically engineered for expressing human lambda immunoglobulin chainNoVirus in combination with Alisertib 30mg/kg for 3 weeksNoNANANANANANANANAFemale athymic nude mice xenograft for MDA-231-lu-P4 (1.0E+6 cells)2.0E+6 TCID50NA Mice median survival time increased to 82.5 days compared to controlIntravenousVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4192Measles virusMV-lambda-NAPRNAParamyxoviridaeGenetically engineered for expressing human lambda immunoglobulin chainYesNoNoNANANANANANANANAFemale athymic nude mice xenograft for MDA-231-lu-P4 (2.0E+6), pleural effusion transthoracic cavity5.0E+5 TCID50NA Mice median survival increased to 57 daysTransthoracicVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4193Measles virusMV-lambda-NAPRNAParamyxoviridaeGenetically engineered for expressing human lambda immunoglobulin chainYesVirus in combination with Alisertib 30mg/kg for 3 weeksNoNANANANANANANANAFemale athymic nude mice xenograft for MDA-231-lu-P4 (2.0E+6), pleural effusion transthoracic cavity5.0E+5 TCID50NA Mice median survival increased to 74 days compared to control 57 daysTransthoracicVirus induce apoptosis process leads to cancer cell deathVirus and drug both cause induction of IL-24 expressionIn clinical trials26272026
OV_4242Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineABC-15.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4243Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineABC-15.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4244Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineABC-15.0E+3 cells per wellNAWST-1 assay1 MOI60% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4245Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineABC-15.0E+3 cells per wellNAWST-1 assay1 MOI45% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4246Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4247Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4248Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI35% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4249Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNational institute of biomedical innovation, JapanHuman nonsmall cell lung carcinoma cell lineNCI-H4415.0E+3 cells per wellNAWST-1 assay1 MOI100% cell killing after day 7NoNoNA No responseNANANANA26317644
OV_4250Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H21705.0E+3 cells per wellNAWST-1 assay1 MOI90% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4251Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H21705.0E+3 cells per wellNAWST-1 assay1 MOI38% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4252Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H21705.0E+3 cells per wellNAWST-1 assay1 MOI20% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4253Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H21705.0E+3 cells per wellNAWST-1 assay1 MOI100% cell killing after day 7NoNoNA No responseNANANANA26317644
OV_4254Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4255Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI55% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4256Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI30% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4257Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H3585.0E+3 cells per wellNAWST-1 assay1 MOI20% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4258Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineCalu-35.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4259Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineCalu-35.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4260Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineCalu-35.0E+3 cells per wellNAWST-1 assay1 MOI42% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4261Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineCalu-35.0E+3 cells per wellNAWST-1 assay1 MOI30% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4262Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H16665.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4263Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H16665.0E+3 cells per wellNAWST-1 assay1 MOI60% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4264Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H16665.0E+3 cells per wellNAWST-1 assay1 MOI40% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4265Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoATCCHuman nonsmall cell lung carcinoma cell lineNCI-H16665.0E+3 cells per wellNAWST-1 assay1 MOI25% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4266Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell linePC-145.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4267Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell linePC-145.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4268Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell linePC-145.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4269Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell linePC-145.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4270Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineA4315.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 1NoNoNA No responseNANANANA26317644
OV_4271Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineA4315.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 3NoNoNA No responseNANANANA26317644
OV_4272Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineA4315.0E+3 cells per wellNAWST-1 assay1 MOI100% cell viability after day 5NoNoNA No responseNANANANA26317644
OV_4273Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNAHuman nonsmall cell lung carcinoma cell lineA4315.0E+3 cells per wellNAWST-1 assay1 MOI80% cell viability after day 7NoNoNA No responseNANANANA26317644
OV_4274Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNANANANANANANANASCID mice xenograft for NCI-H441 cell (5.0E+6)1.0E+6 TCID50NA Reduction in tumor volume 500 cubic millimeter after 40 days compared to control 2500 cubic millimeterIntratumoralNANANA26317644
OV_4633Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCF33NANAWST-1 assay2 MOI50% cell viability after 2 daysNoNoNA No responseNANANANA27093696
OV_4634Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCF33NANAWST-1 assay2 MOI30% cell viability after 4 daysNoNoNA No responseNANANANA27093696
OV_4635Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCF33NANAWST-1 assay2 MOI35% cell viability after 6 daysNoNoNA No responseNANANANA27093696
OV_4636Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCF33NANAWST-1 assay2 MOI30% cell viability after 8 daysNoNoNA No responseNANANANA27093696
OV_4637Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCTBmNANAWST-1 assay2 MOI100% cell viability after 2 daysNoNoNA No responseNANANANA27093696
OV_4638Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCTBmNANAWST-1 assay2 MOI80% cell viability after 4 daysNoNoNA No responseNANANANA27093696
OV_4639Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCTBmNANAWST-1 assay2 MOI60% cell viability after 6 daysNoNoNA No responseNANANANA27093696
OV_4640Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCTBmNANAWST-1 assay2 MOI50% cell viability after 8 daysNoNoNA No responseNANANANA27093696
OV_4641Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCHMmNANAWST-1 assay2 MOI100% cell viability after 2 daysNoNoNA No responseNANANANA27093696
OV_4642Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCHMmNANAWST-1 assay2 MOI40% cell viability after 4 daysNoNoNA No responseNANANANA27093696
OV_4643Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCHMmNANAWST-1 assay2 MOI40% cell viability after 4 daysNoNoNA No responseNANANANA27093696
OV_4644Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoUnivesity of Tokyo JapanCanine mammary cancerCHMmNANAWST-1 assay2 MOI40% cell viability after 4 daysNoNoNA No responseNANANANA27093696
OV_4645Measles virusrMV-SLAMblindRNAParamyxoviridaeR533A substitution was introduced into pMV-HL(7+) and then transfected to vero cell line to produce virus particleYesNoNoNANANANANANANANASCID mice xenograft for CF33 cells1.0E+6 TCID50NA Reduction in tumor volume below 100 cubic mm after 50 days compared to control 700 cubic mmIntratumoralNANANA27093696
OV_5387Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu40% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5388Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, one fold dilution56.778% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5389Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, two fold dilution60.493% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5390Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, three fold dilution38.616% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5391Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, four fold dilution31.039% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5392Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, five fold dilution19.801% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5393Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, one fold dilution53.110% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5394Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, two fold dilution69.954% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5395Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, three fold dilution53.717% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5396Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, four fold dilution31.714% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5397Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, five fold dilution15.174% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5398Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman rhabdomyosarcoma cell lineRD7.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, six fold dilution5.918% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5399Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu46.047% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5400Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, one fold dilution46.047% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5401Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, two fold dilution73.183% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5402Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, three fold dilution58.012% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5403Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, four fold dilution27.350% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5404Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, five fold dilution19.658% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5405Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, six fold dilution14.529% cell growth inhibition after 72 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5406Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, one fold dilution87.81% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5407Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, two fold dilution90.101% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5408Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, three fold dilution74.746% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5409Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, four fold dilution48.477% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5410Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, five fold dilution36.421% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663
OV_5411Measles virusSchwarz vaccine stainRNAParamyxoviridaeNoneYesNoNoICCMGR cell bank unit, IraqHuman glioblastoma cell lineANGM57.0E+3 cells per wellNAMTT assay3.4 × 10⁵ pfu, six fold dilution23.477% cell growth inhibition after 120 hoursNoNoNA No responseNAInduction of apoptosis as measured by mitochondrial permeability apoptosis assayNANA27512663